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A novel peptide targeting gastrin releasing peptide receptor for pancreatic neoplasm detection

Biomater. Sci., 2020, 8,2682-2693
DOI: 10.1039/D0BM00162G, Paper
Yuanbiao Tu, Ji Tao, Fang Wang, Peifei Liu, Zhihao Han, Zhaolun Li, Yi Ma, Yueqing Gu
The designed novel peptide GB-6 with targeted GRPR-binding possesses more favorable pharmacokinetic properties and metabolic stability, as well as superior tumor-targeting ability in pancreatic cancer models, relative to BBN7–14.
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Particle-mediated delivery of frataxin plasmid to a human sensory neuronal model of Friedreich's ataxia

Biomater. Sci., 2020, 8,2398-2403
DOI: 10.1039/C9BM01757G, Communication
Ewa Czuba-Wojnilowicz, Serena Viventi, Sara E. Howden, Simon Maksour, Amy E. Hulme, Christina Cortez-Jugo, Mirella Dottori, Frank Caruso
Multilayered particles in gene therapy for Friedreich's ataxia induce a 27 000-fold increase in frataxin gene expression in a patient-derived cell model.
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Outstanding Reviewers for Biomaterials Science in 2019

Biomater. Sci., 2020, 8,2343-2343
DOI: 10.1039/D0BM90031A, Editorial

We would like to take this opportunity to highlight the Outstanding Reviewers for Biomaterials Science in 2019, as selected by the editorial team for their significant contribution to the journal.
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A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00425A, Paper
Kun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong Wang
A universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.
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A versatile ultrafine and super-absorptive H+-modified montmorillonite: application for metabolic syndrome intervention and gastric mucosal protection

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00474J, Paper
Qiwen Wang, Jie Shen, Enqi Mo, Haotian Zhang, Jianwei Wang, Xiurong Hu, Jun Zhou, Hongzhen Bai, Guping Tang
An H+-modified montmorillonite (H-MMT) was prepared using an acid modification method to obtain powerful absorption ability as a theranostic platform for both metabolic syndrome and gastric mucosa protection.
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Optically controlled hybrid metamaterial of plasmonic spiky gold inbuilt graphene sheets for bimodal imaging guided multimodal therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00312C, Paper
Kunnumpurathu Jibin, Jayaram S. Prasad, Giridharan Saranya, Sachin J. Shenoy, Kaustabh K. Maiti, Ramapurath S. Jayasree
Gold–graphene nanohybrid for simultaneous dual-imaging guided triple therapy as a new paradigm in light-triggered cancer theranostics. The material demonstrates excellent therapeutic efficacy and treatment monitoring features.
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Surface engineering of titanium alloy using metal-polyphenol network coating with magnesium ions for improved osseointegration

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00566E, Paper
Sangmin Lee, Yun-Young Chang, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Yang-Hun Jung, Jeong-Ho Yun, Heungsoo Shin
Although titanium-based implants are widely used in orthopedic and dental clinics, improved osseointegration at the bone–implant interface is still required.
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A biomimetic orally targeted delivery of Bindarit for immunotherapy of atherosclerosis

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00418A, Paper
Luqi Yin, Cuiping Peng, Yue Tang, Yuchuan Yuan, Jiaxing Liu, Tingting Xiang, Feila Liu, Zhou Xing, Xiaohui Li
Monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of atherosclerosis. However, the application of bindarit (a specific synthetic inhibitor of MCP-1) in atherosclerosis has not been confirmed...
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Functionalized Biomaterials to Combat Biofilm

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00526F, Minireview
Dan-ni Huang, Jing Wang, Kefeng Ren, Jian Ji
Pathogenic microbial biofilms readily form on implantable medical devices or human tissues have posed a great threat to worldwide healthcare. Hopes are focused on preventive strategies of biofilms, leaving a...
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Effective intracellular delivery of bevacizumab via PEGylated polymeric nanoparticles targeting CD44v6 receptor in colon cancer cells

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00556H, Paper
Ana Baião, Flávia Sousa, Ana Oliveira, Carla Oliveira, Bruno Sarmento
Colorectal cancer (CRC) is one of the most incident and mortal cancers in the world, mainly due to its metastatic and metabolic ability. CD44 receptor isoform containing exon 6 (CD44v6)...
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Integrated network pharmacology and targeted metabolomics to reveal the mechanism of nephrotoxicity of triptolide

Toxicol. Res., 2019, 8,850-861
DOI: 10.1039/C9TX00067D, Paper
Wei Huang, Chuanxin Liu, Lijuan Xie, Yuming Wang, Yanyan Xu, Yubo Li
Integrated network pharmacology and targeted metabolomics to reveal the nephrotoxicity mechanism of triptolide.
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Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese hamster ovary cells

Toxicol. Res., 2019, 8,868-874
DOI: 10.1039/C9TX00113A, Paper
Neo Mervyn Monaheng, Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel Oluwafemi
In this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay.
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Kaempferol derivatives isolated from Lens culinaris Medik. reduce DNA damage induced by etoposide in peripheral blood mononuclear cells

Toxicol. Res., 2019, 8,896-907
DOI: 10.1039/C9TX00176J, Paper
Magdalena Kluska, Michał Juszczak, Daniel Wysokiński, Jerzy Żuchowski, Anna Stochmal, Katarzyna Woźniak
Bioactive compounds isolated from plants are considered to be attractive candidates for cancer therapy.
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Characteristic synergistic cytotoxic effects toward cells in graphene oxide dressing with cadmium and copper ions

Toxicol. Res., 2019, 8,908-917
DOI: 10.1039/C9TX00146H, Paper
Yiyang Dong, Yulin Chang, Haidi Gao, Victoria Arantza León Anchustegui, Qiang Yu, Haifang Wang, Jia-Hui Liu, Shihui Wang
Cadmium ions exerted synergistic toxic effects with graphene oxide on Hela cells.
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Ex vivo toxicological evaluation of experimental anticancer gold(I) complexes with lansoprazole-type ligands

Toxicol. Res., 2019, 8,885-895
DOI: 10.1039/C9TX00149B, Paper
Natalia Estrada-Ortiz, Elena Lopez-Gonzales, Ben Woods, Stefan Stürup, Inge A. M. de Graaf, Geny M. M. Groothuis, Angela Casini
Novel experimental anticancer gold-based compounds were studied for their mechanisms of toxicity in healthy rat kidney and liver tissues, using the Precision Cut Tissue Slices (PCTS) technique.
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Gynura divaricata ameliorates hepatic insulin resistance by modulating insulin signalling, maintaining glycolipid homeostasis and reducing inflammation in type 2 diabetic mice

Toxicol. Res., 2019, 8,928-938
DOI: 10.1039/C9TX00191C, Paper
Xuan Dong, Shu-Xiang Zhao, Bing-Qing Xu, Yu-Qing Zhang
Oral lyophilized powder of Gynura divaricata, an edible medicinal plant, can alleviate both hyperglycaemia and hepatic insulin resistance in type 2 diabetic mice.
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Lipoic acid antagonizes paraquat-induced vascular endothelial dysfunction by suppressing mitochondrial reactive oxidative stress

Toxicol. Res., 2019, 8,918-927
DOI: 10.1039/C9TX00186G, Paper
Li Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhou
α-Lipoic acid antagonizes paraquat toxicity.
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Thyroid endocrine status and biochemical stress responses in adult male Wistar rats chronically exposed to pristine polystyrene nanoplastics

Toxicol. Res., 2019, 8,953-963
DOI: 10.1039/C9TX00147F, Paper
Fatemeh Amereh, Akbar Eslami, Simin Fazelipour, Mohammad Rafiee, Mohammad Ismail Zibaii, Mohammad Babaei
At this time, little is known about the long-term effects of micro(nano)plastics on public health. In the present study, early warning signs of thyroid endocrine disruption were noticed in adult Wistar rats from the ingestion of virgin polystyrene nanoparticles.
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Environmental distribution of the neurotoxin L-BMAA in Paenibacillus species

Toxicol. Res., 2019, 8,781-783
DOI: 10.1039/C9TX00203K, Viewpoint
Peter B. Nunn, Geoffrey A. Codd
The neurotoxic amino acid, 3-N-methyl-2,3-diaminopropanoic acid (BMAA), known in plants of the genus Cycas and in aquatic cyanobacteria and other organisms, is a component of antibiotic peptides in two species of Paenibacillus.
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Biogenic Aspergillus tubingensis silver nanoparticles’ in vitro effects on human umbilical vein endothelial cells, normal human fibroblasts, HEPG2, and Galleria mellonella

Toxicol. Res., 2019, 8,789-801
DOI: 10.1039/C9TX00091G, Paper
Cristiane Angélica Ottoni, Durvanei Augusto Maria, Priscila Jane Romano de Oliveira Gonçalves, Welington Luiz de Araújo, Ana Olívia de Souza
Biogenic silver nanoparticles are ecofriendly and offers valuable possibilities of applications in several industrial areas.
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Cadmium telluride quantum dot-exposed human bronchial epithelial cells: a further study of the cellular response by proteomics

Toxicol. Res., 2019, 8,994-1001
DOI: 10.1039/C9TX00126C, Paper
Yan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. Lau
A comparative proteome analysis was conducted to identify global changes in the protein expression profiles of cadmium telluride quantum dot-exposed human bronchial epithelial BEAS-2B cells.
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Effects of moderate red wine on cardiovascular risk factors in diabetics: a systematic review and meta-analysis of randomized controlled trials

Toxicol. Res., 2019, 8,979-987
DOI: 10.1039/C9TX00227H, Paper
Saavia Alice Naame, Decheng Li, Ruixue Huang
Diabetes mellitus is of major public health concerns; its incidence is continuously increasing.
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Methanol extract of Iphiona aucheri ameliorates CCl4 induced hepatic injuries by regulation of genes in rats

Toxicol. Res., 2019, 8,815-832
DOI: 10.1039/C9TX00157C, Paper
Jawaid Ahmed Zai, Muhammad Rashid Khan, Zaib un Nisa Mughal, Riffat Batool, Irum Naz, Sonia Maryam, Zartash Zahra
Alteration in expression of ER stress associated genes, inflammatory genes and antioxidant biochemical induced with CCl4 in liver of rats were restored towards the control rats by co-administration of methanol extract of Iphiona aucheri to rats.
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Nanoparticle induced barrier function assessment at liquid–liquid and air–liquid interface in novel human lung epithelia cell lines

Toxicol. Res., 2019, 8,1016-1027
DOI: 10.1039/C9TX00179D, Paper
Open Access
Lars Leibrock, Sandra Wagener, Ajay Vikram Singh, Peter Laux, Andreas Luch
To answer questions about nanoparticle toxicity, translocation and biokinetics following inhalation exposure, in vitro models should have functional barrier properties to mimic the in vivo situation as closely as possible.
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AIIB extends $500 mn loan to India to deal with coronavirus crisis

The bank's board of directors has approved a loan to India to strengthen the preparedness of the country's national health system




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Only 13% of industrial units resume ops after Odisha eases lockdown

Micro units in the state have not been able to resume operations to catch up with their larger peers




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Amarinder Singh asks administration to ensure welfare of migrant workers

The chief minister asked the industry ministry to "aggressively" pursue the development of the four industrial parks already announced by the state government in the budget for this fiscal.




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Export contraction in April could surpass March's steep 25-year decline

Major forex earning sectors cite lack of labour, funds and key supplies




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Govt hikes market borrowing limit by over 50% to Rs 12 trillion

The government resorts to market borrowing to make up for the mismatch between its revenue and expenditure.




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Govt hikes borrowing limit by over 50% to Rs 12 trn as virus grips economy

Sources say the Centre has asked RBI to do whatever to keep yields in check, which may result in massive secondary market bond purchases




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Lockdown period not to be counted for determining residency of NRIs: CBDT

There were apprehensions that this extended stay could lead to these individuals becoming Indian residents as per Section 6 of the Income Tax Act




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Covid-19: Relief for NRIs, foreign visitors as tax residency rules eased

The government imposed a lockdown on March 24 and is yet to open up travel, including international flights.




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Tamil Nadu CM asks PM to keep Electricity Amendment Bill on hold till talks

Proposed Bill takes away certain powers of the State government, and seeks to bring in changes in the existing Electricity Act that would make power utilities in the public sector totally unviable




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Adityanath seeks ways to boost tax revenue as UP misses April target by 90%

Chairing a review meeting here, Adityanath directed the revenue minister and other senior officials to look at additional sources of revenue and accelerate tax collection




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Miners want mandatory capex rule relaxed as workers stay away fearing Covid

None of the merchant mines in Odisha whose lease validity expired by March 31 has been able to restart. Though the successful bidders have got LoI, they awaiting formal vesting orders




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Probing permanent dipoles in CdSe nanoplatelets with transient electric birefringence

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR00884B, Paper
Ivan Dozov, Claire Goldmann, Patrick Davidson, Benjamin Abécassis
Transient electric birefringence experiments with colloidal suspensions of zinc-blende CdSe semiconducting nanoplatelets prove that these particles bear a large ground-state electric dipole despite the cubic structure of bulk zinc-blende CdSe.
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Release of graphene-related materials from epoxy-based composites: characterization, quantification and hazard assessment in vitro

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10245K, Paper
Open Access
Woranan Netkueakul, Daria Korejwo, Tobias Hammer, Savvina Chortarea, Patrick Rupper, Oliver Braun, Michel Calame, Barbara Rothen-Rutishauser, Tina Buerki-Thurnherr, Peter Wick, Jing Wang
We measured the cytotoxicity of pristine GRMs and the abraded particles from epoxy/GRM composites, which indicated low risks to consumers of such composites.
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Conductive-bridging random-access memories for emerging neuromorphic computing

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01671C, Review Article
Jun-Hwe Cha, Sang Yoon Yang, Jungyeop Oh, Shinhyun Choi, Sangsu Park, Byung Chul Jang, Wonbae Ahn, Sung-Yool Choi
This review covers CBRAM-based artificial synapses and neurons towards emerging computing applications from the operation principles of CBRAMs to state-of-the-art experimental demonstrations.
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Dual-sensitized Upconversion-assisted, Triple-band Absorbing Luminescent Solar Concentrators

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01008A, Paper
Sung Kyung Nam, Kiwon Kim, Ji-Hwan Kang, Jun Hyuk Moon
Luminescent solar concentrator-photovoltaic systems (LSC-PV) harvest solar light by using transparent photoluminescent plates, which is expected to be particularly useful for building-integrated PV applications. LSC panels that absorb multiple wavelength...
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Hybrid Phase 1T/2H-MoS2 with Controllable 1T Concentration and Its Promoted Hydrogen Evolution Reaction

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02525A, Paper
Yuxiao Zhang, Yasutaka Kuwahara, Kohsuke Mori, Catherine Louis, Hiromi Yamashita
MoS2 has been investigated as a low-cost alternative to Pt in electrochemical hydrogen evolution reaction. One of the promising method to further activate MoS2 is phase engineering. MoS2 generally exhibit...
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A super stable assembled P nanowire with variant structural and magnetic/electronic properties via transition metal adsorption

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02176H, Paper
Sukai Wang, Jinxing Gu, Yinan Dong, Linwei Sai, Fengyu Li
By means of first-principles calculations, we systematically investigated the structure, stability, magnetic and electronic properties of one-dimensional P nanowire (1D-P10 NW) assembled by Pn subunits (n = 2, 8) and...
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Multi-praseodymium-and-tungsten bridging octameric tellurotungstate and its 2D honeycomb composite film for detecting estrogen

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01901A, Paper
Yan Zhang, Jun JIang, Yifan Liu, Pan Li, Yong Liu, Lijuan Chen, Junwei Zhao
Under coordination driving force of tungsten and rare-earth (RE) bridges, we synthesized a novel giant multi-tungsten-and-RE—bridging octameric tellurotungstate (TT) [H2N(CH3)2]16K8Na6H10[Pr8(H2O)20W16O48][B-α-TeW9O33]8·70H2O (1) in CH3CN-H2O mixed solvent. The cluster anion {[Pr8(H2O)20W16O48][B-α-TeW9O33]8}40– features...
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Facile fabrication of sponge-like porous micropillar arrays via an electrochemical process

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01518K, Paper
Deyin Zheng, Chang-Hwan Choi, Xin Zhao, Guangyi Sun
Highly ordered and aligned pore structures perpendicular to the exposed surfaces are achieved on the surfaces of 3D Si microstructures.
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Wrinkle-induced highly conductive channels in graphene on SiO2/Si substrate

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01406K, Paper
Ruisong Ma, Jiajun Ma, Jiahao Yan, Liangmei Wu, Wei Guo, Shuai Wang, Qing Huan, Lihong Bao, Sokrates T Pantelides, Hong-Jun Gao
Graphene wrinkle is a quasi-one-dimensional structure and can alter the intrinsic physical and chemical activity, modify the band structure and introduce transport anisotropy in graphene thin films. However, their quasi-one-dimensional...
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Correction: Anomalous polarization dependence of Raman scattering and crystallographic orientation of black phosphorus

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR90098B, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jungcheol Kim, Jae-Ung Lee, Jinhwan Lee, Hyo Ju Park, Zonghoon Lee, Changgu Lee, Hyeonsik Cheong
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Pristine Graphene Induces Innate Immune Training

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/C9NR09661B, Paper
Filipa Lebre, John B Boland, Pedro Gouveia, Aoife Gorman, Mimmi Lundahl, Fergal J O'Brien, Jonathan N Coleman, Ed Lavelle
Graphene-based materials are of increasing interest for their potential use in biomedical applications. However, there is a need to gain a deeper understanding of how graphene modulates biological responses before...
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Spin-coated fluorinated PbS QD superlattice thin film with high hole mobility

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02299C, Paper
Pan Xia, Daniel Davies, Bijal Patel, Maotong Qin, Zhiming Liang, Kenneth R Graham, Ying Diao, Ming Lee Tang
Motivated by the oleophobic and electron-withdrawing nature of perfluorocarbons, we explore the effect of a trifluoromethyl coating on lead sulfide quantum dots (PbS QDs) in thin film transistor (TFT) geometry....
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MOF-derived lithiophilic CuO nanorod arrays for stable lithium metal anodes

Nanoscale, 2020, 12,9416-9422
DOI: 10.1039/D0NR01091J, Paper
Lei Wei, Li Li, Teng Zhao, Nanxiang Zhang, Yuanyuan Zhao, Feng Wu, Renjie Chen
MOF-derived CuO nanorod arrays with lithiophilic groups were fabricated on a Cu foil current collector (CuO NAs/CF) to produce stable lithium metal batteries with uniform, dendrite-free Li deposition.
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Analysis of sparse molecular distributions in fibrous arrangements based on the distance to the first neighbor in single molecule localization microscopy

Nanoscale, 2020, 12,9495-9506
DOI: 10.1039/C9NR10805J, Paper
Alan M. Szalai, Lucía F. Lopez, Miguel Ángel Morales-Vásquez, Fernando D. Stefani, Pedro F. Aramendía
We introduce a robust and sensitive metric to characterize the underlying structure responsible for the molecular distribution, even at a very low labeling density.
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Facile synthesis of core–shell structured Si@graphene balls as a high-performance anode for lithium-ion batteries

Nanoscale, 2020, 12,9616-9627
DOI: 10.1039/D0NR01346C, Paper
Anif Jamaluddin, Bharath Umesh, Fuming Chen, Jeng-Kuei Chang, Ching-Yuan Su
Encapsulating silicon (Si) nanoparticles with graphene nanosheets in a microspherical structure is proposed to increase electrical conductivity and solve stability issues when using Si as an anode material in lithium-ion batteries (LIBs).
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