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Assessment of optimized FRET substrates as universal corona- and picornavirus main protease substrates for screening assays

RSC Adv., 2024, 14,35438-35446
DOI: 10.1039/D4RA06573E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Conrad Fischer, Tayla J. Van Oers, Marco J. van Belkum, Tess Lamer, Aaron Romney, Pu Chen, M. Joanne Lemieux, John C. Vederas
A short FRET peptide was identified as a universal substrate for selected coronavirus Mpros. Kinetic parameters, buffer stability and Z'-assay suggest this substrate as an excellent target for CoV-Mpro HT inhibitor screening assay development.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Self-immolative polydisulfides and their use as nanoparticles for drug delivery systems

RSC Adv., 2024, 14,35568-35577
DOI: 10.1039/D4RA07228F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Katharina Völlmecke, Maurice Kramer, Corinna Horky, Oliver Dückmann, Dennis Mulac, Klaus Langer, Dirk Kuckling
Polydisulfide based nanoparticles can be degraded by glutathione (GSH) to deliver hydrophobic drugs.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Advances in quinoxaline derivatives: synthetic routes and antiviral efficacy against respiratory pathogens

RSC Adv., 2024, 14,35400-35423
DOI: 10.1039/D4RA04292A, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Fateme Dehnavi, Malihe Akhavan, Ahmadreza Bekhradnia
3D lung visualization showing COVID-19 infection areas alongside respiratory pathogens. The antiviral drug structure and comparison of healthy vs. infected lungs demonstrate how the drug could restore lung health.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Design, synthesis, and in vitro and in vivo biological evaluation of triazolopyrimidine hybrids as multitarget directed anticancer agents

RSC Adv., 2024, 14,35239-35254
DOI: 10.1039/D4RA06704E, Paper
Open Access
Heba A. Adawy, Samar S. Tawfik, Abdullah A. Elgazar, Khalid B. Selim, Fatma E. Goda
In response to the urgent need for new anti-proliferative agents, four novel series of triazolopyrimidine compounds (7a–e, 9a–d, 11a–f, and 13a–e) were synthesized and evaluated for in vitro and in vivo anticancer efficacy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Retraction: Fabrication of novel quantum dots for the estimation of COVID-19 antiviral drug using green chemistry: application to real human plasma

RSC Adv., 2024, 14,35696-35696
DOI: 10.1039/D4RA90133A, Retraction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Baher I. Salman, Adel Ehab Ibrahim, Sami El Deeb, Roshdy E. Saraya
The content of this RSS Feed (c) The Royal Society of Chemistry




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Electromagnetic wave effects on Mn-doped superparamagnetic iron oxide nanofluids: applications in enhanced oil recovery

RSC Adv., 2024, 14,35671-35678
DOI: 10.1039/D4RA04500A, Paper
Open Access
Mohamad Amin Bin Hamid, Beh Hoe Guan, Chan Kar Tim, Hassan Soleimani
This study reveals that both direct current (DC) and alternating current (AC) electromagnetic fields can effectively reduce the interfacial tension (IFT) of Mn-doped Fe3O4 nanofluids, with AC fields showing more predictable and pronounced effects.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Synthesis of supramolecular polymers with calix[4]arene and β-cyclodextrin and their application in heavy metal ion absorption

RSC Adv., 2024, 14,35697-35703
DOI: 10.1039/D4RA05559D, Paper
Open Access
Jian-Jian Bian, Shi-Jin Tang, Jiao Miao, Rui Lin, Guo-Li Huang, Ming-Yu Teng, Xiao-Mei Li
Two categories of supramolecular polymer monomers were produced by introducing the ureidopyrimidone quadruple-hydrogen bonding assemblies on the calix[4]arene and the β-cyclodextrin host units, which adsorbed up to 99% of Pb2+ and Cd2+.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Review of iodine behavior from nuclear fuel dissolution to environmental release

RSC Adv., 2024, 14,35255-35274
DOI: 10.1039/D4RA06494A, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Chelsie L. Beck, Juan Cervantes, Steven Chiswell, Allison T. Greaney, Katherine R. Johnson, Tatiana G. Levitskaia, Leigh R. Martin, Gavin McDaniel, Stephen Noble, Jason M. Rakos, Brian J. Riley, Andrew Ritzmann, Joel M. Tingey
During nuclear fuel reprocessing, radioiodine, can be released.
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A facile synthesis of iron oxide nanoparticles as a nano-sensor to detect levofloxacin and ciprofloxacin in human blood and evaluation of their biological activities

RSC Adv., 2024, 14,36093-36100
DOI: 10.1039/D4RA05024J, Paper
Open Access
Erum Hasan, Ziana Manzar, Nabeel Haroon, Ali Raza, Syed Nawazish Ali, Mehreen Lateef, Sabira Begum
New bioactive magnetic nanoparticles were synthesized and stabilized by 3-aminobenzoic acid (3-ABA) utilized in detection of levofloxacin and ciprofloxacin.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Porous, environment-friendly chitosan-ZIF composite fibers for dye adsorption

RSC Adv., 2024, 14,36063-36072
DOI: 10.1039/D4RA06883A, Paper
Open Access
Xuebin Hou, Wei Chen, Meihong Fan, Chen Shi
Porous, environment friendly ZIF-8@CS composite fibers were fabricated through wet spinning and self-assembly method, which effectively remove dyes from water and exhibit excellent recyclability.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Synthesis of green fluorescent carbon dots and their application in mercury ion detection

RSC Adv., 2024, 14,36273-36280
DOI: 10.1039/D4RA06635A, Paper
Open Access
Juan Hou, Qinqin Chen, Xiangzhi Meng, Huiling Liu, Wei Feng
Green fluorescent carbon dots were prepared for effective detection of Hg2+ ions through fluorescence quenching, demonstrating high sensitivity and selectivity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Haryana Congress again urges Speaker to disqualify MLA Kiran Choudhry from State Assembly

Since the senior leader had joined the BJP, according to the Tenth Schedule of the Constitution, ‘any member of a House who voluntarily gives up their membership of a political party is liable to be disqualified,’ the Congress said




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Purpose of Maratha quota stir not to aggravate social tensions, says Jarange-Patil 

The activist reiterates that he won’t be changing his stance on Maratha reservation, warns that leaders opposing him will not get any votes from the community in upcoming Assembly election




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Two arrested in M.P. for allegedly forcing Dalit man to drink urine; counter FIR against him for alleged extortion

Police said that an investigation had been launched but claimed that no evidence to support the victim’s claims has been found so far




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Farmers in Rajasthan set to get electricity for irrigation of crops during day time

A memorandum of understanding was signed for two gas-based power plants in Jaipur, says Minister Nagar




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‘Attack’ on Uddhav convoy ‘inspired by Abdali’s supari’, says Sanjay Raut

After the incidents on August 9 and 11, a war of words broke out between the party leaders




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Hindu man from Bangladesh becomes first person to get citizenship under CAA 

The Hindu man has been staying in Silchar town since 1988




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Protests erupt in Assam as first CAA beneficiary granted citizenship

Students’ organisations and Opposition parties said citizenship to a Bangladesh-born man was a violation of the Assam Accord of 1971




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Shots fired at house of Manipur college principal

Police said masked men on a scooter fired five rounds on Tuesday evening. In July 17, miscreants had lobbed a grenade, but it did not explode and was later disposed of by a special squad




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Search continues for second day for missing training aircraft in Jharkhand

Aircraft with two persons onboard belongs to Alchemist Aviation flying school in Jamshedpur




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BJP has no leaders in Jharkhand, they ‘hire’ from other States to handle political scenario here: CM Hemant Soren

Without naming anyone, Mr. Soren said the Opposition is engaged in divisive politics and that there is no agenda or vision shown by them




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Outrage after minor girl’s gang rape in Assam

Some locals found her lying semi-conscious by the roadside on her way back home from tuition classes




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2 killed, 20 injured as police open fire during Assam eviction drive

Tension began after the evicted people reoccupied the cleared spaces around Thursday noon and confronted the officials; security stepped up




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Madhya Pradesh Cabinet meets in tribal queen’s capital on her 500th birth anniversary

The Cabinet has approved additional assistance of up to ₹3,900 per hectare to farmers under the Rani Durgavati Shri Anna Protsahan Yojana, over the minimum purchase price




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NSCN (I-M) seeks third-party intervention to break talks deadlock

Accusing the Centre of betraying the Framework Agreement of 2015, the Naga extremist group led by Thuingaleng Muivah threatened to return to violent ways




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Curbing the doping scourge: Anju Bobby George, Ashwini Nachappa have their say

The two champion athletes agree on both the crux of the problem — incorrect or insufficient guidance — and the reasons for it — increased competition and desperation to succeed — but differ in how accountability should be apportioned




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Nayana shocks Asian champ Sumire to win gold in Taiwan Athletics Open

Animesh impresses in Spain, Eldhose and Jesse strike gold in France




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Third Indian Grand Prix track and field: Another chance for many stars to stake their claim for Paris Olympics

There are no eye-popping names in the fray, perhaps because the National inter-state championship is scheduled in close proximity (June 27-30 in Panchkula, Haryana).




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Sprint hurdler Kiran breaks Maymon’s under-18 National record




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Norman Pritchard: Colonised India’s first athlete to win two medals in same Olympics

While the International Olympic Committee (IOC) lists him as an Indian, World Athletics (formerly IAAF) credits his Olympic medals to Britain.




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Paris Olympics: Afghan sprinter Yousoufi tells girls not to let others make decisions for them

Competing in her third Olympics — Rio de Janeiro and Tokyo — Yousofi finished with a time of 13.42 seconds, slower than the 13.29 three years ago.




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Ugandan Olympic runner Cheptegei dies after being set on fire by boyfriend

The 2024 Paris Olympian was doused in petrol and set on fire by her boyfriend, making her the third female athlete to be killed in the country since 2021




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Sebastian Coe, multi-millionaire Johan Eliasch among seven candidates for IOC presidency

The IOC, with 111 members currently, is in charge of the Olympic Games and the multi-billion dollar industry linked to the world's biggest multi-sports event.




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India Open under-23 athletics: Talented athletes eager to prove their worth

The athletes will look to perform well ahead of the Asian and World championships next year.




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Faster, higher, longer: decathlete Jashbir Nayak sets his sights on the Asian Games

The 22-year-old has advanced swiftly in a short period, registering an overall increase of 1244 points since last May. This has both underlined his potential in athletics’ toughest discipline and propelled his ambition to excel at the prestigious continental event in two years’ time




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PIX: India crush Bangladesh in first T20I in Gwalior

IMAGES from the 1st T20I between India and Bangladesh played in Gwalior on Sunday




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PICS: Young, Ravindra see off Bumrah, Siraj in triumph

India arrived in Bengaluru seeking a big win over the 2021 champions to improve their chances of making a third successive final in June 2025, but will now need to battle to keep alive their run of 18 straight home series victories since 2012.




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PIX: Happy campers, Kiwis celebrate with their kids

And joining the players in celebration were their families.




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Zika virus case detected in Gujarat, patient discharged after treatment

As a precautionary measure, health authorities visited the area where the person lives and carried out surveillance and tracking exercises; however no person in the area showed any symptoms of Zika infection, a statement from the government said




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Taking newborn screening, as a birth right, ahead in Karnataka

NBS is a public health programme that helps in identifying serious developmental and genetic disorders in newborns through biochemical tests conducted after birth.




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T.N. Health Department takes cancer screening to women at their workplace

To give better access to women for screening of cancer, the Health Department is taking their programmes to work sites and also encouraging women to come in for annual check-ups




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Lahore air pollution: UNICEF warns of ‘devastating effects’ on children, pregnant women

Toxic smog has shrouded Pakistan's cultural capital of Lahore and 17 other districts in Punjab since October 2024.




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Britain to become first G7 country to end coal power as last plant closes

It will end over 140 years of coal power in Britain




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Iran launches missile barrage at Israel, warns of ‘crushing’ retaliation if provoked

Israeli air defences intercepted many of the missiles, with no reported casualties. Meanwhile, the US pledged military support for Israel, and the UN called for a ceasefire amid concerns over escalating regional conflict 




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What to know about Iran's missile barrage, Israel's ground operations in Lebanon

Israeli officials said Iran would pay a price for the strike




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Apparent Israeli airstrike on mosque in central Gaza kills at least 18 people

The latest strikes add to the mounting Palestinian death toll in Gaza, which is now nearing 42,000




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Israel-Iran tensions escalate: Retaliatory strikes target military installations in Tehran

The Israeli military cited continuous Iranian attacks from multiple fronts since October 7, affirming Israel’s right to retaliate




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European banks to extend dealing with Indian clearing firms

Europe’s authorities set the deadline last year after their request for co-supervision of European trades settled through Indian clearing houses was denied by the Reserve Bank of India



  • Money & Banking

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Netanyahu’s office is accused of leaks to thwart Gaza cease-fire

Many in Israel’s security establishment dismissed the demand and accused Netanyahu of avoiding a deal to keep the war going




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North Korea joins Ukraine war for the first time

Another Kyiv official said Ukraine's army fired artillery at North Korean soldiers in Russia's Kursk border region