Controls on pharmaceutical production in the EU should be changed to guard against the spread of antibiotic resistance, protect wildlife and improve transparency in the industry, a team of scientists from Sweden and the UK recommends. The scientists propose 10 changes to the environmental risk assessment (ERA) of pharmaceuticals.

Pharmaceutical pollution of marine environments has important biological consequences for aquatic organisms. This study investigated the effects on mussels of treatment with environmentally relevant levels of an antidepressant, fluoxetine, and a beta-blocker, propranolol, using biomarkers including DNA damage. The results showed that mussels are most vulnerable to these drugs in combination.

The framework for a Europe-wide biomonitoring programme has been established by a new study. The preliminary investigation of 17 European countries showed that monitored levels of toxic chemicals varied significantly between countries. Although the levels were mostly within recognised health-based guidance values, in a few cases these values were exceeded. The researchers suggest that a fully-fledged European biomonitoring programme would help to develop policies to avert public health risks presented by environmental chemicals.

Different management practices using pesticides affect the diversity, number and ecological traits of ground spiders in apple orchards, a new study finds. Because spiders are viewed as good indicators of the quality of an entire ecosystem, the results reveal that organic orchard management may be better for local management and landscape characteristics when compared to those with pesticide use.

Environmental specimen banks (ESBs) first emerged in the 1960s and are now essential to environmental management across the globe. ESBs sample and archive environmental specimens and can be used to identify the distributions of chemicals within ecosystems and trace their exposure over time. This study uses the German ESB to illustrate their potential for chemicals monitoring in the EU.

Environmental risk assessment is challenging because of the complexity of the physical and ecological systems around us. Natural disasters, the spread of dangerous substances, ecosystem changes leading to food and health security issues, and the emergence of new materials, new events and new knowledge make it essential to update our understanding continually, to be able to identify threats and opportunities for timely action. This Thematic Issue presents some collaborative and integrated paths towards forward-thinking assessment and management of environmental risks.

New research has combined two different techniques for identifying hazards and assessing risks into a single dynamic risk assessment process. The new approach fills a gap in many current risk assessment techniques as it can be applied throughout the lifetime of a process, not just during its design phase, taking into account new information to update risk assessments and calculations systematically.

A methodology for assessing ‘chemical footprints’ has been developed by researchers to evaluate human pressures and the impact of chemicals released by the production and consumption of goods. The study integrates a life-cycle approach with different methodologies, such as those developed in the context of environmental risk assessment and sustainability science, with the aim of assessing the extent to which chemicals impact on ecosystems beyond their ability to recover (i.e. surpass planetary boundaries).

Chemicals regulation in Europe could be improved through integrated risk assessment, says an EU project. The project team presents a range of perspectives on how the integration of hazard, exposure and socio-economic assessments can be promoted and implemented.

To assess the risk posed by metals in the aquatic environment, Biotic Ligand Models (BLMs) were developed, and are now considered suitable for use in regulatory risk assessments. This study reviews the advantages of BLMs and BLM-based software tools, providing examples from across the EU, and offers recommendations for their widespread implementation.

Researchers have recommended that fish from some sections of the River Po and the River Lambro, one of the Italian River Po tributaries, should not be eaten due to high levels of some endocrine-disrupting chemicals in the river sediments and fish. This recommendation is based on an extensive update regarding pollution levels of such substances in the rivers.

Farming fish together with seaweed and other species could help improve the sustainability of aquaculture and reduce pollution. A new study provides a tool for designing sustainable fish farming systems and calculates their potential to recycle waste. An example of a salmon farming system incorporating seaweed and sea urchins could reduce nitrogen releases to the environment by 45%.

Widespread use of antibiotics has led to pollution of waterways, potentially creating resistance among freshwater bacterial communities. A new study looked for antibiotic resistance genes in a river basin in Spain, revealing that wastewater discharges can promote the spread of antibiotic resistance in streams and small rivers.

The non-restricted production and use of pharmaceuticals and personal care products (PPCPs) has led to their presence in effluents from treatment plants, which can pose a threat to aquatic organisms downstream. This study analysed the breakdown of six common chemicals in four Danish treatment plants. The findings shed new light on the factors affecting removal of PPCPs from waste, showing that the composition of waste is more important than the design of the treatment plant.

The use of two methods to systematise evidence-evaluation methods is reviewed in nine EU regulations dealing with chemicals risk assessment. The majority of frameworks were found to promote the use of ‘weight of evidence’ or ‘systematic review’-style approaches, but the study found a lack of structured, consistent and detailed guidance for these approaches. The researchers recommend this guidance is developed collaboratively by European regulatory agencies and points to best practice for this guidance.

How does the law protect the environment? The responsibility for the legal protection of the environment rests largely with public authorities such as the police, local authorities or specialised regulatory agencies. However, more recently, attention has been focused on the enforcement of environmental law — how it should most effectively be implemented, how best to ensure compliance, and how best to deal with breaches of environmental law where they occur. This Thematic Issue presents recent research into the value of emerging networks of enforcement bodies, the need to exploit new technologies and strategies, the use of appropriate sanctions and the added value of a compliance assurance conceptual framework.

Chemicals are everywhere and new substances are regularly being introduced to the market. However, only some pose a risk to the environment. How do we decide which of them to monitor? A new study using a database of chemicals found in fish in the Baltic Sea has assessed which chemicals are commonly monitored. The researchers suggest that monitoring is biased towards known, already regulated hazardous chemicals, and recommend changes to address other chemicals.

Azole fungicides are active ingredients in a range of pharmaceutical and personal care products, and are also used in agriculture. This study reviewed the sources, presence and risks of these compounds in the environment, finding evidence of toxic effects on aquatic organisms. The researchers provide directions for future research and warn caution should be exercised until more toxicity data becomes available.

Researchers have developed a new approach to hierarchise pesticides based on their risk to or via the aquatic environment, which has been implemented in the Pinios River Basin of Central Greece. The analysis indicated that a number of pesticides were found in concentrations that could cause negative impacts on aquatic ecosystems. The results provide detailed information to inform decisions regarding the monitoring of pesticides in the Pinios River Basin and outline an approach that could be used in other watersheds.

Micropollutants — small, persistent and biologically active substances — are found in aquatic environments all over the world and can have negative effects on plants, animals and humans. The EU recently adopted a ‘watch list’ of potential priority substances, including pesticides, pharmaceuticals and personal care products that need to be monitored to determine their environmental risk. A new study reviews data on their worldwide occurrence and options for their removal from wastewater, and from surface and groundwater used to produce drinking water.

Researchers have shown that in the Baltic Sea the abundance of common fish species, used as an indicator of ecosystem health, is influenced by climate-related oceanic conditions at a local scale, such as sea temperature. The researchers suggest, therefore, that the environmental status of coastal fish communities in the region should be assessed and managed at a local scale.

A method for developing ecological scenarios for assessing pesticides’ risks to aquatic wildlife has been developed. It is based on the selection of vulnerable taxa according to biological trait information, exposure conditions and environmental properties. The method should help decision makers define what to include in ecological models used for future pesticide risk assessments and is proposed as a way to increase the ecological realism of pesticide risk assessment.

Pesticides used on agricultural land can leach into nearby surface water; this is called run-off and can harm aquatic ecosystems. This study evaluated the potential of ditches to reduce run-off, using Italy’s Po Valley as a case study. Grassy ditches were able to significantly reduce the concentration of herbicides, even during extreme flooding. The researchers therefore suggest that the promotion of vegetated ditches via agri-environment schemes would be beneficial for pesticide mitigation.

Fertilisers have boosted crop yields but at the same time can have negative effects on the environment. This study investigates fertiliser ‘ecoinnovations’, with reduced environmental impact, in Germany. By gathering the views of experts, producers, traders and farmers, the researchers make recommendations for increasing uptake of environmentally friendly fertilisers, including increasing knowledge and awareness among traders and farmers.

A range of legislation, including the Marine Strategy Framework Directive (MSFD), is designed to ensure the ‘Good Environmental Status’ (GES) of EU seas by 2020. Researchers have assessed the MSFD in relation to existing maritime policies, concluding that coordination between directives is important to achieve GES.

A recent study has evaluated frameworks and tools used in Europe to assess the potential health and environmental risks of manufactured nanomaterials. The study identifies a trend towards tools that provide protocols for conducting experiments, which enable more flexible and efficient hazard testing. Among its conclusions, however, it notes that no existing frameworks meet all the study’s evaluation criteria and calls for a new, more comprehensive framework.

A common anti-parasitic drug used to control gastrointestinal worms in livestock has been shown to inhibit seed germination of three common grassland species. This recent study is the first to show that anthelmintics may negatively affect plant regeneration. The researchers say that treatments should be carefully timed in order to avoid the strongest impact of the drugs on germination and the consequential negative affect on grassland regeneration.

New figures on how much titanium dioxide nanomaterial (TiO2-NM) could be released into the environment from photocatalytic cement — a new type of self-cleaning cement — are presented in a recent study. Based on experimental test results, the researchers estimate that between 0.015% and 0.033% of photocatalytic cement’s TiO2-NM content could potentially escape over several years of cement use, depending on the level of cement porosity. The study could help inform environmental risk assessment of TiO2-NM, as well as safer design of nano-products (i.e. commercialised products incorporating nanomaterials).

What has been the impact of Agricultural Environment Schemes (AES) on European farming? These schemes provide payments to farmers in return for the implementation of agri-environmental measures to encourage positive environmental outcomes and as a counterbalance to the profit incentive. The schemes might concentrate on low-intensity production, organic or integrated management or enhancement of biodiversity on farmland. This Thematic Issue presents recent peer-reviewed research examining the impacts AES have had on European farm ecosystems, biodiversity and farmers – and to what extent AES have benefited a range of animals and plants by increasing the number of individuals and species.

Judging whether to replace a hazardous conventional chemical in a product with a nanomaterial — i.e. to assess which is the safer alternative — is challenging for many reasons. A new study suggests that chemical-alternative assessment frameworks could be adapted to better assess engineered nanomaterials with the help of new tools which provide data on hazards of, and exposure to, nanomaterials.

A new study has mapped levels of chemical elements found in European agricultural soils. In most places, unusually high concentrations are linked to geology, such as high levels of arsenic in the Massif Central in France. Human activity is to blame in some small areas, for example high concentrations of mercury were found near London and Paris. Abnormal concentrations, both too low and too high, could pose an environmental risk. This new data can be used in conjunction with the REACH Regulation1 and can help identify areas where action may be needed in relation to toxic elements in the environment.

Municipal wastewater is a major source of pharmaceuticals in the aquatic environment. Results from a recent study suggest that collecting and treating urine separately from other forms of sewage could be a cost-effective way to reduce the harmful effects of pharmaceuticals on the environment, while also providing a source of nutrients for fertilising agricultural crops.

Biological control agents are an environmentally-friendly way of controlling pests and diseases on crops and are advocated in the EU’s Sustainable Use of Pesticides Directive1. The authors of a new review of the current state of biological control refer to a recent UN report2 which states that it is possible to produce enough food to feed a world population of nine billion with substantially less chemical pesticides — and even without these pesticides if sufficient effort is made to develop biocontrol-based Integrated Pest Management (IPM) methods. The study suggests that policy measures can speed up the development and use of environmentally-friendly crop protection.

UV treatment does not always turn hazardous water pollutants into harmless substances. Recent lab tests suggest that the toxicity of the antibiotic linezolid to microorganisms appeared to increase post-treatment. This research did find, however, that UV treatment successfully reduced the antimicrobial activity of four other antibiotics tested, plus four artificial sweeteners.

Evaluating the level of danger to human health from exposure to multiple chemicals in contaminated sites is a complex task. To address this difficulty, researchers have developed a new screening tool that can be incorporated into public health risk assessment, which may include polluted former industrial plants, waste dumps, or even land where pesticides have been used. This ‘hazard index’ approach indicates when risk to health is high, which organs are most affected, and where further evaluation should be conducted in the context of environmental or occupational exposure at such sites.

A new study has analysed the environmental impact of 15 products containing nanosilver, highlighting the contribution of this novel material to the items’ overall environmental burden. The findings show that nanosilver impacts, such as fossil fuel depletion and human-health impacts, are relative to content, and can be marginal when considered in the context of the product’s other materials. Based on their results, the researchers recommend considering the overall impacts and benefits of nano-enabled products in evaluation and environmental guidance on their development.

A recent study has assessed the environmental impact of a group of technology-critical elements (TCEs) — niobium (Nb), tantalum (Ta), gallium (Ga), indium (In), germanium (Ge) and tellurium (Te) — that, to date, have been relatively under-researched. The researchers reviewed published concentrations of these elements in environmental archives and evaluated trends over time in surface waters. Overall, they found no evidence that the rising use of these elements in modern technologies is causing environmental concentrations to increase on a global level. These findings are relevant to future policy discussions regarding the source, usage and presence of less-studied TCEs, particularly in relation to critical raw metals.

Plastic waste in the environment presents cause for concern, but scientific understanding of its exact impacts is still in its infancy. A team of Dutch scientists has presented recommendations on how to develop a new assessment method which provides clear, specific evidence on the risks of plastic waste. Once developed, this method could inform scientifically sound policies for managing plastic waste.

According to most EU legislation, regulatory assessment of chemicals should make use of all available and relevant studies. However, in practice, assessments tend to be predominantly based on research sponsored and provided by industry as part of their legal obligations to show safety of their products, rather than on independent peer-reviewed findings. To bridge this science–policy gap, a team of Swedish researchers, in combination with regulators at three Swedish governmental agencies, have published a list of recommendations aimed at increasing the regulatory usability and impact of academic research. This advice is aimed at researchers, for whom it clarifies relevant regulatory data requirements and quality criteria. However, it is also relevant to policymakers, in that it highlights the advantages and availability of relevant, reliable peer-reviewed research for use in the regulatory assessment of chemicals. The study’s recommendations contribute to the formulation of more science-based, sustainable policies.

Environmental pollution is putting amphibians and reptiles at risk, yet these animals are not included in regulations regarding the environmental risk assessment (ERA) of pesticides. The extent to which other species already used in pesticide toxicity assessment (including fish, birds and mammals) can serve as effective surrogates is currently under debate. This study conducts a systematic review of the available literature. The results reveal a positive correlation between toxicity recorded on fish and aquatic amphibians, but indicate that birds and mammals are generally not good surrogates for reptiles and terrestrial amphibians. Moreover, some chemical-dependent trends were detected, with a number of insecticides found to be more toxic to amphibians or reptiles than to potential surrogates. These findings highlight an urgent need for further research to reduce uncertainties and contribute to future policymaking regarding the protection of amphibians and reptiles from potentially harmful pesticides.

Currently laws and regulations governing nanotechnology are fragmented and do not take account of the unique properties of nanomaterials, the effect of which on humans and the environment are not yet fully understood, argue researchers in a new study. In the study, a network of European researchers propose a new universal regulatory framework that deals specifically with nanomaterials. The framework should help policymakers, organisations and researchers evaluate the risks of any existing materials and new nanomaterials entering the market. It should also help SMEs and large companies use safer products and processes, limit the potential adverse effects of nanomaterials on workers and consumers, reduce the cost of insurance and reduce the risk of governments having to pay out money in the future due to unforeseen accidents or diseases.

Copper (Cu) is frequently used in agricultural practices, particularly in fungicides, used extensively in the management of permanent crops, such as vineyards, olive groves, and fruit orchards — all crops of significant economic importance to the EU. An investigation into the factors influencing Cu distribution in the topsoils of 25 EU Member States has identified that, in conjunction with other factors such as topsoil properties, land cover, and climate, such agricultural management practices play a role in influencing Cu concentration. The analysis used 21 682 soil samples from the EU-funded Land Use and Coverage Area frame Survey (LUCAS)¹ and found that vineyards, olive groves, and orchards had the highest mean soil Cu concentrations of all land use categories. The findings highlight the major impact of land use and agricultural practices on soil Cu concentrations and emphasise a need for more sustainable land management practices.

Parasitoid wasps (Trichogramma pretiosum) are increasingly being used as a biological control agent in agriculture. Since insecticides are often applied to the same crops, it is necessary to assess the effects of different insecticides on this insect. However, the majority of studies have focused on evaluating the lethal, but not sublethal, effects of insecticides. A new study has evaluated the sublethal effects on T. pretiosum of nine insecticides commonly used in soybean production in Brazil. Overall, just three of the nine insecticides tested did not appear to have any harmful sublethal effects on T. pretiosum. This study highlights the importance of considering sublethal, as well as lethal, effects when assessing insecticide selectivity.

A new study has raised safety concerns over PFO4DA, a substance increasingly used as a substitute for PFOA, a harmful persistent organic pollutant (POP), in plastic production. PFO4DA was found to cause liver damage to mice in lab tests, and is also an environmental pollutant. The researchers caution that it may not be a suitable alternative to PFOA.

ew research indicates that educational policies can affect the environmental, health and financial impacts of school commuting. It found that the most effective school-enrolment policy for reducing traffic emissions is to send children to the school closest to where they live.

Despite some criticisms about the Clean Development Mechanism (CDM), a new study has indicated that CDM projects in China could be making sizeable improvements to air quality. The research predicted, in particular, that the projects' associated SO2 reductions would make up 13-14 per cent of the reductions in 2010 towards the national target level.

Assessing the impact of large urban areas on air quality and climate change needs an integrated approach with a range of spatial and temporal scales, according to researchers. The EU-funded MEGAPOLI project considers time scales from seconds to decades and spatial scales from local to global.

Pedestrians are exposed to different levels of pollution on the pavements depending on how parked cars at the roadside are arranged, according to the first in a series of new studies in this area. The researchers modelled different parking regimes and found that less pollution reached the pavement when cars were parked sideways on, rather than at an angle to the street. Their results may help urban planners design more pedestrian-friendly streets.

Researchers have presented an extensive analysis of the role of nanomaterials in environmental remediation and monitoring. Nanomaterials can be used to clean up toxins and bacteria from natural waters, wastewaters and the air.

Low emission zones (LEZs) that restrict old vehicles in city centres may need implementation in combination with other traffic policies to have greater impacts on air quality, according to new research. A study that measured emission levels before and after the introduction of LEZs in five Dutch cities indicated that air pollution concentrations were reduced but not to a statistically significant level.