ut

Approach is to treat every game with utmost respect: Gukesh




ut

Chennai Grandmasters | For Arjun, a fresh outlook and approach




ut

Race walker-turned-coach Basant Rana upbeat about the future of the sport in the country

He says that the competition in Asia is tough due to the Chinese and Japanese athletes; however, he is confident that with the support of the government, AFI and corporates, the Indians can bridge the gap by participating in quality competitions on a regular basis




ut

Iranian charged for plotting Trump assassination tasked with targeting Israeli tourists in Sri Lanka: U.S authority

Shakeri is an Islamic Revolutionary Guard Corps (IRGC) asset, remains at large and is believed to reside in Tehran, Iran




ut

Trump rules out former Cabinet members Mike Pompeo, Nikki Haley in his administration

Pompeo served as the CIA Director and Secretary of State in his first term, Haley served as his ambassador to the United Nations in the first two years of Trump’s presidency




ut

Donald Trump speaks to Putin, warns against escalating war in Ukraine: report

Donald Trumps’s representativessaid he also expressed an interest in further conversations to discuss “the resolution of Ukraine’s war soon.”




ut

Canadian Foreign Ministry denies blocking Indian-diaspora media outlet Australia Today

The news site and video of media comments by both India’s Foreign Minister Jaishankar and Australia’s Foreign Minister Wong can be easily and freely viewed in Canada, the Ministry said




ut

Kremlin denies Putin and Trump spoke on phone

Kremlin spokesman Dmitry Peskov told journalists that the Washington Post report was "simply false information", denying any phone call took place




ut

North Korea ratifies mutual defence treaty with Russia

The report came amid international criticism over increasing military cooperation between the two countries, with North Korea having sent tens of thousands of troops to Russia to support its war against Ukraine




ut

COP29 day 2 highlights: U.N. chief cautions world leaders, says ‘pay up or face climate-led disaster for humanity’

More than 75 leaders are expected in Baku over two days but the heads of some of the most powerful and polluting economies are not attending this year’s summit




ut

Israeli strikes set off explosions in Beirut suburbs and kill 14 Palestinians in Gaza, medics say

The strike came hours after the Israeli military announced an expansion of the zone, where it has told Palestinians evacuating from other parts of Gaza to take refuge




ut

South Korea's Yoon practises golf to prepare for future Trump meets

Analysts said Mr. Yoon may seek to find a way to capitalise on a personal friendship with Mr. Trump to advance Seoul's interests as Trump's "America First" foreign policy plan




ut

35 dead as driver hits crowd at sports centre in South China

Police detained a 62-year-old man at the sports centre in the southern Chinese city of Zhuhai following the ramming; the suspect was dissatisfied with the split of financial assets in his divorce, according to preliminary investigation




ut

SRM University-AP wins men’s south zone badminton tournament




ut

Police ask devotees to exercise caution while taking holy dip in canals, rivers in Andhra Pradesh’s Kurnool

“Police bandobust would be arranged at important points as people throng river banks,” SP Bindhu Madhav said and asked the devotees to follow the directions and suggestions of the Police for incident-free festivities




ut

Court orders community service for 28-year-old youth in theft case

The verdict is claimed to be the first-of-its-kind in Andhra Pradesh after the implementation of the Bharatiya Nyaya Sanhita (BNS) and Bharatiya Suraksha Sanhita (BNSS) laws




ut

T. Bapi Reddy takes charge as the new Executive Officer of Srikalahasti temple

The Shaivite temple is famously known as ‘Dakshina Kashi’ (Varanasi of the South) and is thronged by tens of thousands of devotees from across the country




ut

Paddy farmers of Kruthivennu, Bantumilli mandals in Krishna district of A.P. stage dharna demanding water for rabi crop

With no water in the irrigation canals salinity was causing problems for the crop in the coastal region, farmers’ body leader said




ut

CM Chandrababu Naidu and Home Minister Vangalapudi Anitha express deep condolences over electrocution tragedy in East Godavari

The Chief Minister directed authorities to provide the best possible medical care to the injured and announced a compensation of ₹5 lakh for the families of each deceased




ut

Residents stage protest against pollution caused by Vijayawada Thermal Power Station

People residing in the colonies at Ferry, Kondapalli and Ibrahimpatnam organised a protest and appealed to the government to protect them from pollution




ut

A.P. government appoints Inquiry Authority to probe role of revenue officers in alleged land scam in Vizianagaram

Revenue Department Special Chief Secretary directs the Inquiring Authority to submit the inquiry report within a period of six weeks




ut

Nellore police arrests auto-driver accused in minor girl rape case




ut

Surface charge-induced electrospray for high-throughput analysis of complex samples and electrochemical reaction intermediates using mass spectrometry

Anal. Methods, 2024, 16,2002-2008
DOI: 10.1039/D4AY00276H, Communication
Yajie Huang, Yajun Zheng, Qianqian Zuo, Zhiming Zhang, Lixuan Zhu, Yun Li, Zhiping Zhang
A novel surface charge induced electrospray ionization is proposed due to its features of no contact between sample solution and metal electrode, fast analytical process (less than 40 s), and high analytical sensitivity.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

High performance and recyclable Ag/ZnO/PM substrate for the detection of organic pollutants

Anal. Methods, 2024, 16,2051-2062
DOI: 10.1039/D4AY00103F, Paper
Yixin Shao, Hongxin Cai, Lingling Yan, Hang Yu, Qiang Hu, Liang Chen, Haitao Zong, Xiufang Hou
A sensitive and recyclable substrate was fabricated through in situ reduction of silver nanoparticles on zinc oxide nanorods.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

A screening method for the quantitative determination of selective androgen receptor modulators (SARMs) in capsules by high resolution 19F- and 1H-NMR spectroscopy

Anal. Methods, 2024, 16,2135-2146
DOI: 10.1039/D4AY00188E, Paper
Alessandro Maccelli, Anna Borioni, Federica Aureli, Maria Cristina Gaudiano, Livia Manna, Mariangela Raimondo
A new method for rapid determination of selective androgenic receptor modulators (SARMs) andarine, cardarine, ligandrol, ostarine and S-23 in capsules by 1H- and 19F-high resolution NMR spectroscopy was described and validated.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Luminescent and time-resolved determination of gemifloxacin mesylate in pharmaceutical formulations and spiked blood plasma samples using a lanthanide complex as a probe

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00236A, Paper
Gasser M. Khairy, Rania M. Goda, Zeinab M. Anwar, Mohamed M. Aboelnga, Axel Duerkop
A new luminescent europium probe for the determination of the antibiotic gemifloxacin is presented. Time-resolved luminescence enables its quantitation in pharmaceutical formulations and blood samples.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Discrimination of Diptera order insects based on their saturated cuticular hydrocarbon content using a new microextraction procedure and chromatographic analysis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00214H, Paper
Open Access
Lixy Olinda León-Morán, Marta Pastor-Belda, Pilar Viñas, Natalia Arroyo-Manzanares, María Dolores García, María Isabel Arnaldos, Natalia Campillo
The nature and proportions of hydrocarbons in the cuticle of insects is characteristic of the species and age. Chemical analysis of cuticular hydrocarbons allows species discrimination, which is of great...
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Solid phase microextraction – the future technique in pharmacology and coatings trends

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00187G, Minireview
Aleksandra Owczarzy, Karolina Kulig, Katarzyna Piordas, Patrycja Piśla, Patrycja Sarkowicz, Wojciech Rogóż, Małgorzata Maciążek-Jurczyk
Traditional sample preparation techniques based on liquid-liquid extraction (LLE) or solid phase extraction (SPE) often suffer from a major error due to the matrix effects caused by significant co-extraction of...
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Caffeine quantification in dietary supplements using high-throughput on-line solid phase extraction coupled to Venturi easy ambient sonic-spray ionization mass spectrometry

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00333K, Paper
David Ulisses Tega, Luan Felipe Campos Oliveira, Patrick Cesar Ferreira, Bruna Beatriz Soldera, Heliara Dalva Lopes Nascimento, Marcos Nogueira Eberlin, Alessandra Sussulini
Optimization of a LC-V-EASI-MS system. Employment of LC-V-EASI-MS and online SPE to enhance analytical performance for caffeine determination reaching 90 s per sample.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Analysing micro- and nanoplastics with cutting-edge infrared spectroscopy techniques: a critical review

Anal. Methods, 2024, 16,2177-2197
DOI: 10.1039/D3AY01808C, Critical Review
Open Access
Junhao Xie, Aoife Gowen, Wei Xu, Junli Xu
In this review, we discussed and compared the applications of Fourier transform infrared spectroscopy, quantum cascade laser infrared spectroscopy, atomic force microscopy-based infrared spectroscopy, and optical photothermal infrared spectroscopy in MNP research from multiple perspectives.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

A chemodosimetric chemosensor for the ratiometric detection of nerve agent-mimic DCP in solution and vapor phases

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00451E, Paper
Shilpita Banerjee, Pintu Ghosh, Anirban Karak, Dipanjan Banik, Ajit Kumar Mahapatra
The probe MNFZ undergoes a hydrolysis reaction in the presence of DCP to exhibit a naked eye color change from blue to cyan. It was successfully applied to sense DCP in the vapor phase.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Novel advanced materials and magnetic solid phase extraction as approaches in sample preparation to enhance the analysis of ochratoxin A in peanuts

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00246F, Paper
Bingchen Wang, Yifan Wang, Xiuyuan Zhang, Kuo He
In order to improve the detection efficiency of ochratoxin, a superparamagnetic nano-material was synthesized for solid phase extraction of ochratoxin.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Solutions and Tools for Dealing with Broken Links in Web Pages

A couple of months ago a post by Leo Blanchette got to the front page of Hacker News and there was an interesting discussion on dealing with broken links and external content – the main problem being links that become out of date due to paywalls, altered content, or content getting taken down.

I’ve been running this blog since May 2008. If you’ve run a content-driven site for even a fraction of that, you know that link rot is a problem. In this post I’ll go over some of the suggestions in that thread along with some tools to use to check for broken links.

The post Solutions and Tools for Dealing with Broken Links in Web Pages appeared first on Impressive Webs.



  • HTML5
  • Web Design Articles

ut

Detecting Specific Text Input with HTML and CSS

Recently I came across a CodePen demo by a developer/engineer named Jane that was Tweeted out by Šime Vidas. The demo has a neat collection of HTML and CSS tricks rolled into one that I thought was worth examining in detail.

The page displays a secret message based on specific text input. Ok, that’s no big deal, right? Well this is done using pure HTML and CSS – no JavaScript. I’ve seen stuff like this before, but I thought it would be cool to break down exactly how this works. There are a few notable things happening in the code so I’ll break down each of the parts.

The post Detecting Specific Text Input with HTML and CSS appeared first on Impressive Webs.




ut

YouTube’s Time-Based UX Problem for Live Sports

I like to play beach volleyball here in the Toronto area. I also watch beach volleyball on YouTube, which includes a lot of live streams from the AVP league in the US. It's a fun sport that I recommend to anyone looking for a new athletic competition to follow.

In most leagues and tournaments, beach volleyball games have a 3-set format, with each set finishing when a team reaches 21 points (or higher if they're not yet ahead by 2). The third set (played if needed) will go up to 15 points (again, win by 2). Some leagues/tournaments will play all three sets up to 15. It depends on the venue, tournament, etc.

The post YouTube’s Time-Based UX Problem for Live Sports appeared first on Impressive Webs.



  • UX
  • Web Design Articles

ut

How mobile data can help rationalise bus routes




ut

Good, but not enough: On the extended coverage of the Ayushman Bharat scheme

Extension of free health coverage to all over 70 years is good, but more needs to be done  




ut

A way out: On the government and doctor-led protests in West Bengal

The West Bengal government must enable the changes doctors want to see




ut

Staying the course: On the fight against air pollution in the Indo-Gangetic plains

The Centre and the States need to fight air pollution together 




ut

​Steady but slow: On the VIPER mission, lessons for India

India’s space programme needs more resources to realise its full potential




ut

Growth prescription: On the latest World Economic Outlook 

The IMF’s ‘mediocre’ medium-term outlook merits policy attention




ut

​Beautifully vague: On the Tamilaga Vettri Kazhagam’s inaugural conference  

Actor Vijay seems to be targeting both the BJP and the DMK 




ut

Pathogenesis of Alzheimer's disease and therapeutic strategies involving traditional Chinese medicine

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00660G, Review Article
Shutang Li, Jinfei Yang
As research on AD has progressed, TCM and its active ingredients have increasingly played a crucial role in clinical treatment. This article summarizes extracts from TCM and briefly elucidates their pharmacological mechanisms against AD.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia

RSC Med. Chem., 2024, 15,3495-3506
DOI: 10.1039/D4MD00275J, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Thomas J. Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R. G. Galan, Morgan Jay-Smith, Kate S. Harris, Carole J. R. Bataille, Thomas R. Jackson, Douzi Zhang, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. Russell
The optimisation of a class of AML differentiation agents is described to show improved potency, solubility and stability, reduced off target toxicity, and tumour regression in a murine model in vivo.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

SLL-1A-16 suppresses proliferation and induces autophagy in non-small-cell lung cancer cells via the AKT/mTOR signaling pathway

RSC Med. Chem., 2024, 15,3460-3468
DOI: 10.1039/D4MD00405A, Research Article
Xiaoqin Luo, Jin Wang, Ruichang Wang, Jiabing Lian, Mengnan Guo, Hongrui Zhou, Mengxue Zhang, Zhe Yang, Xiaolong Li, Xianran He, Xiuli Bi
Schematic of proposed mechanism for the treatment of the SLL-1A-16 inhibiting the proliferation in NSCLC.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Next-generation EGFR tyrosine kinase inhibitors to overcome C797S mutation in non-small cell lung cancer (2019–2024)

RSC Med. Chem., 2024, 15,3371-3394
DOI: 10.1039/D4MD00384E, Review Article
Debasis Das, Lingzhi Xie, Jian Hong
Prospects of novel fourth-generation EGFR-TKIs overcoming C797S-mediated resistance in non-small cell lung cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Rationally modified SNX-class Hsp90 inhibitors disrupt extracellular fibronectin assembly without intracellular Hsp90 activity

RSC Med. Chem., 2024, 15,3609-3615
DOI: 10.1039/D4MD00501E, Research Article
Open Access
Gciniwe S. Mathenjwa, Abir Chakraborty, Abantika Chakraborty, Ronel Muller, Mathew P. Akerman, Moira L. Bode, Adrienne L. Edkins, Clinton G. L. Veale
Rationally modified Hsp90 inhibitors which retained of on-target activity but showed no engagement of intracellular Hsp90, or stimulation of the heat shock response, were found to significantly alter the extracellular fibronectin network.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Sidechain structure–activity relationships of cyclobutane-based small molecule αvβ3 antagonists

RSC Med. Chem., 2024, 15,3616-3624
DOI: 10.1039/D4MD00306C, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Adam Throup, Manar Saleh Zraikat, Andrew Gordon, Shohreh Jafarinejad Soumehsaraei, Kathrin D. Haase, Laurence H. Patterson, Patricia A. Cooper, Katherine Hanlon, Paul M. Loadman, Mark Sutherland, Steven D. Shnyder, Helen M. Sheldrake
Cyclobutanes provide a versatile scaffold for the synthesis of small molecule integrin antagonists with good metabolic stability and in vivo tolerability.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

A novel, glutathione-activated prodrug of pimasertib loaded in liposomes for targeted cancer therapy

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00517A, Research Article
Open Access
Arianna Amenta, Susanna Comi, Marcelo Kravicz, Silvia Sesana, Antonia Antoniou, Daniele Passarella, Pierfausto Seneci, Sara Pellegrino, Francesca Re
A novel, glutathione-activated prodrug of pimasertib (PROPIMA) has been developed. PROPIMA showed ability to inhibit tumour cell migration and proliferation controlled over time, while also achieving a high incorporation rate into liposomes.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ut

Therapeutic upregulation of DNA repair pathways: strategies and small molecule activators

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00673A, Review Article
Juhyung Song, Cheoljun Park, Francis E. B. Cabanting, Yong Woong Jun
Potential therapeutic target proteins for upregulating DNA repair system are reviewed, along with reported small-molecule activators.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry