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Encyclopedia of nanotechnology / Bharat Bhushan, editor

Online Resource




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Environmental nanotechnology: applications and impacts of nanomaterials / Mark R. Wiesner, editor, Jean-Yves Bottero, editor

Hayden Library - T174.7.E58 2016




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Advanced manufacturing, electronics and microsystems / edited by Matthew Laudon, Bart Romanowicz

Barker Library - T174.7.A38 2015




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Nanovate: commercializing disruptive nanotechnologies / Mohab Anis, Ghada AlTaher, Wesam Sarhan, Mona Elsemary

Online Resource




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Nanomaterial safety in the workplace: pilot project for assessing the impact of the NIOSH Nanotechnology Research Center / Eric Landree, Hirokazu Miyake, Victoria A. Greenfield

Hayden Library - T174.7.L36 2015




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Nanoparticles / Raz Jelinek

Hayden Library - T174.7.J45 2015




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Nanotechnology: synthesis to applications / edited by Sunipa Roy, Chandan Kumar Ghosh, and Chandan Kumar Sarkar

Hayden Library - T174.7.N345524 2018




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NanoInnovation 2017: 26-29 September 2017, Rome, Italy / editors, Marco Rossi, Luciana Dini, Daniele Passeri and Marco Vittori Antisari

Online Resource




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Applied nanotechnology: the conversion of research results to products / Jeremy J. Ramsden, University of Buckingham, Buckingham, UK

Online Resource




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Nanotechnology-based targeted drug delivery systems for lung cancer / edited by Prashant Kesharwani

Barker Library - T174.7.N37347 2019




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Encyclopedia of nanotechnology edited by Bharat Bhushan

Online Resource




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NanoInnovation 2018: 11-14 September 2018, Rome, Italy / editors, Marco Rossi, Luciana Dini, Daniele Passeri and Marco Vittori Antisari

Online Resource




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Nanotechnology applications in dairy science: packaging, processing, and preservation / edited by Lohith Kumar Dasarahally-Huligowda, Megh R. Goyal, Hafiz Ansar Rasul Suleria

Online Resource




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Quaternary ecology, evolution and biogeography [electronic resource] / Valentí Rull.

London : Academic Press, 2020.




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School closures and the online preparedness of children during the COVID-19 pandemic [electronic resource] / by Marc Frenette, Kristyn Frank, and Zechuan Deng

[Ottawa] : Statistics Canada = Statistique Canada, 2020




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COVID-19 pandemic [electronic resource]: school closures and the online preparedness of children / by Marc Frenette, Kristyn Frank and Zechuan Deng

[Ottawa] : Statistics Canada = Statistique Canada, 2020




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Canadians report lower self-perceived mental health during the COVID-19 pandemic [electronic resource] / by Leanne Findlay and Rubab Arim

[Ottawa] : Statistics Canada = Statistique Canada, 2020




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Asymmetric copper-catalyzed conjugate additions of organometallic reagents in syntheses of natural compounds and pharmaceuticals

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00278J, Review Article
Denisa Vargová, Ivana Nemethova, Radovan Sebesta
Stereoselective synthesis of complex molecular structures is needed in medicine as well as in crop-protection. Copper-catalyzed 1,4-additions of organometallic reagents is a robust C-C bond formation strategy applicable in a...
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Synthesis of Biaryl Ketones by Arylation of Weinreb Amides with Functionalized Grignard Reagents under Thermodynamic Control vs. Kinetic Control of N,N-Boc2-Amides

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00813C, Communication
Guangchen Li, Michal Szostak
A highly efficient method for chemoselective synthesis of biaryl ketones by arylation of Weinreb amides (N-methoxy-N- methylamides) with functionalized Grignard reagents is reported. This protocol offers rapid entry to functionalized...
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Highly Z-selective synthesis of 1,3-oxathiol-2-ylidenes and 4-methylene-oxazolidine-2-thiones via atom-specific 5-exo-dig cyclization of propargyl alcohol with isothiocyanate

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00083C, Paper
S. Antony Savarimuthu, D. G. Leo Prakash, S. Augustine Thomas, Thirumanavelan Gandhi, Mrinal K. Bera
The Z-selectivity observed in imine and alkene motifs after 5-exo-dig cyclization of propargyl alcohol and isothiocyanate is rare in the literature and this selectivity can be attributed to electronic and steric factors of the imine and alkene motif respectively.
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Selenium-promoted electrophilic cyclization of arylpropiolamides: synthesis of 3-organoselenyl spiro[4,5]trienones

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00609B, Paper
Ana Maria S. Recchi, Pedro H. P. Rosa, Davi F. Back, Gilson Zeni
A synthetic approach to regioselective synthesis of 3-organochalcogenyl spiro[4,5]trienones and 3-organochalcogenyl[4,5]triene-2,6-diones is described through the reaction of arylpropiolamides with an electrophilic chalcogen source.
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Proof of concept for poor inhibitor binding and efficient formation of covalent adducts of KRASG12C and ARS compounds

Org. Biomol. Chem., 2020, 18,3069-3081
DOI: 10.1039/D0OB00071J, Paper
Maria G. Khrenova, Anna M. Kulakova, Alexander V. Nemukhin
Comprehensive molecular modeling and kinetic analysis reveal a novel mechanism of the inhibition of the oncogenic mutant of the “undruggable” KRAS protein.
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A modular approach to the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine

Org. Biomol. Chem., 2020, 18,3047-3068
DOI: 10.1039/D0OB00078G, Paper
Ramona Schütz, Maximilian Meixner, Iris Antes, Franz Bracher
A modular short-step synthesis of the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine was developed employing N-acyl-Pictet–Spengler reaction and Ullman diaryl ether synthesis as central steps.
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Recent progress in (hetero)arene cation radical-based heteroarene modification

Org. Biomol. Chem., 2020, 18,2975-2990
DOI: 10.1039/D0OB00441C, Research Article
Hai-Lei Cui
This review summarizes the advances in heteroarene modification via transformations of in situ generated (hetero)arene cation radicals, ranging from 2010 to 2020.
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Stereoselective preparation of P,axial-stereogenic allenyl bisphosphine oxides via chirality-transfer

Org. Biomol. Chem., 2020, 18,3017-3021
DOI: 10.1039/D0OB00390E, Communication
Mao-Ran Qiu, Hong-Xing Zheng, Jing-Jing Ye, Bing-Xia Yan, Chang-Qiu Zhao, Qiang Li
Allenyl bisphosphine oxides having variable chirality were prepared in high dr, which was controlled by chiral carbon and phorphorus.
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Regio- and stereoselective synthesis of 1,4-enynes by iron-catalysed Suzuki–Miyaura coupling of propargyl electrophiles under ligand-free conditions

Org. Biomol. Chem., 2020, 18,3022-3026
DOI: 10.1039/D0OB00357C, Communication
Ryosuke Agata, Siming Lu, Hiroshi Matsuda, Katsuhiro Isozaki, Masaharu Nakamura
The first iron-catalysed cross coupling of propargyl electrophiles with lithium alkenylborates has been developed.
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Photochemical rearrangement of diarylethenes: synthesis of functionalized phenanthrenes

Org. Biomol. Chem., 2020, 18,3098-3103
DOI: 10.1039/D0OB00296H, Paper
A. V. Zakharov, A. V. Yadykov, A. G. Lvov, E. A. Mitina, V. Z. Shirinian
The photocyclization of diarylethenes bearing naphthalene units was explored and a convenient protocol for the synthesis of functionalized phenanthrenes was proposed.
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Metal-free cascade reactions of aziridines with arylalkynes and aryldiazoniums: facile access to arylazopyrrolines

Org. Biomol. Chem., 2020, 18,3149-3157
DOI: 10.1039/D0OB00346H, Paper
Jing Rong, Hao Jiang, Sijing Wang, Zhenni Su, Huiyan Wang, Chuanzhou Tao
A novel and facile approach to synthesize arylazopyrroline scaffolds via metal-free cascade reactions of aziridines with arylalkynes and aryldiazoniums has been developed, providing access to a variety of 4-arylazo-2-pyrrolines in a highly concise fashion.
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Catalyst and solvent switched divergent C–H functionalization: oxidative annulation of N-aryl substituted quinazolin-4-amine with alkynes

Org. Biomol. Chem., 2020, 18,3032-3037
DOI: 10.1039/D0OB00318B, Communication
Siddi Ramulu Meesa, Praveen Kumar Naikawadi, Kishan Gugulothu, K. Shiva Kumar
Catalyst and solvent controlled ortho/peri site-selective oxidative annulation of C–H bonds of N-aryl substituted quinazolin-4-amines with internal alkynes.
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Regioselective hydroarylation and arylation of maleimides with indazoles via a Rh(III)-catalyzed C–H activation

Org. Biomol. Chem., 2020, 18,3093-3097
DOI: 10.1039/D0OB00353K, Paper
Asim Kumar Ghosh, Sadhanendu Samanta, Payel Ghosh, Sukanya Neogi, Alakananda Hajra
Switchable Rh(III)-catalyzed highly regioselective hydroarylation and oxidative arylation of maleimides with 2-arylindazoles via C–H activation have been demonstrated.
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Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides

Org. Biomol. Chem., 2020, 18,3142-3148
DOI: 10.1039/D0OB00407C, Paper
Kun Huang, Andrea Marchesi, Kristian Hollingsworth, Peter Both, Ashley P. Mattey, Edward Pallister, Helene Ledru, Simon J. Charnock, M. Carmen Galan, W. Bruce Turnbull, Fabio Parmeggiani, Sabine L. Flitsch
A new α1,4 galactosyltransferase has been characterised and used for the synthesis of natural and non-natural cell surface trisaccharide antigens.
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Construction of pH sensitive smart glutathione peroxidase (GPx) mimics based on pH responsive pseudorotaxanes

Org. Biomol. Chem., 2020, 18,3125-3134
DOI: 10.1039/D0OB00122H, Paper
Jiaxi Li, Wenlong Jia, Ganghui Ma, Xiaoyin Zhang, Shaojie An, Tao Wang, Shan Shi
Two pH-sensitive smart glutathione peroxidase (GPx) mimics were developed by using pH-responsive pseudorotaxanes based on cucurbit[6]uril and organoselenium compounds.
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Sub-stoichiometric reductive etherification of carbohydrate substrates and one-pot protecting group manipulation

Org. Biomol. Chem., 2020, 18,3135-3141
DOI: 10.1039/D0OB00252F, Paper
Chiao Wen Chen, Ching Chi Wang, Xin Ru Li, Henryk Witek, Kwok-Kong Tony Mong
Polymethylhydrosiloxane (PMHS): a sub-stoichiometric reducing agent for reductive etherification of carbohydrate substrates and its application for one-pot protecting group manipulation
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Synthesis, radiolabelling and initial biological characterisation of 18F-labelled xanthine derivatives for PET imaging of Eph receptors

Org. Biomol. Chem., 2020, 18,3104-3116
DOI: 10.1039/D0OB00391C, Paper
Marc Pretze, Christin Neuber, Elisa Kinski, Birgit Belter, Martin Köckerling, Amedeo Caflisch, Jörg Steinbach, Jens Pietzsch, Constantin Mamat
Two new fluorine-18-labelled xanthine derivatives with high binding affinity were synthesised as PET-radioligand candidates for Eph receptors.
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Non-biaryl atropisomerism at the C–B bond in sterically hindered aminoarylboranes

Org. Biomol. Chem., 2020, 18,3007-3011
DOI: 10.1039/D0OB00421A, Communication
Mélodie Birepinte, Frédéric Robert, Sandra Pinet, Laurent Chabaud, Mathieu Pucheault
Sterically hindered aminoarylboranes with atropisomerism about the C–B bond were prepared and resolved by chiral stationary phase HPLC.
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Experimental results and computational insight into sequential reactions of β-(2-aminophenyl)-α,β-ynones with aryl isocyanates/benzoyl isothiocyanate

Org. Biomol. Chem., 2020, 18,3177-3189
DOI: 10.1039/D0OB00087F, Paper
Antonio Arcadi, Massimiliano Aschi, Marco Chiarini, Fabio Marinelli, Vincenzo Marsicano, Gustavo Portalone
The selective formation of quinazoline vs. benzoxazine  and benzothiazine derivatives from β-(2-aminophenyl)-α,β-ynones and aryl isocyanates/benzoyl isothiocyanate was explored. DFT calculations provide a plausible rationale.
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Pseudo-enantiomeric carbohydrate-based N-heterocyclic carbenes as promising chiral ligands for enantiotopic discrimination

Org. Biomol. Chem., 2020, 18,3012-3016
DOI: 10.1039/D0OB00155D, Communication
Alexander S. Henderson, John F. Bower, M. Carmen Galan
The practical synthesis of pseudo-enantiomeric carbohydrate-based NHC–Rh complexes bearing C1 or C3 sterically differentiated positions is reported. We show that steric bulk at either C1 or C3 leads to enantiotopic discrimination in the hydrosilylation of acetophenone.
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Synthesis and aggregation behaviour of single-chain, 1,32-alkyl-branched bis(phosphocholines) – part 2: lateral chain length triggers self-assembling from sheets to fibres to vesicles

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00534G, Paper
Kai Gruhle, Max Tuchtenhagen, Sindy Müller, Gerd Hause, Annette Meister, Simon Drescher
The synthesis of six single-chain, alkyl-branched bolalipids and first investigations of the lyotropic behaviour of these lipids are reported.
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Synthesis of disaccharide modified berberine derivatives and their anti-diabetic investigation in zebrafish using a fluorescence-based technology

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00327A, Paper
Lizhen Wang, Haotian Kong, Meng Jin, Xiaobin Li, Rostyslav Stoika, Houwen Lin, Kechun Liu
Diglucose modified berberine derivatives can dramatically promote the uptake of 2-NBDG in both zebrafish larvae and their eyes.
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Dearomatization of 3-cyanoindoles by (3 + 2) cycloaddition: from batch to flow chemistry

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00582G, Communication
Maxime Manneveau, Saori Tanii, Fanny Gens, Julien Legros, Isabelle Chataigner
(3 + 2) Dearomatizing cycloaddition of 3-cyanoindoles occurs in smooth conditions with a non-stabilized azomethine ylide, to yield tricyclic indolines in only 1 min under microflow conditions using 3 equiv of the dipole precursor vs. 6 equiv. in a batch reactor.
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Half-sandwich (η5-Cp*)Rh(III) complexes of pyrazolated organo-sulfur/selenium/tellurium ligands: efficient catalysts for base/solvent free C–N coupling of chloroarenes under aerobic conditions

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00538J, Paper
Charu Sharma, Avinash Kumar Srivastava, Kamal Nayan Sharma, Raj Kumar Joshi
Three new Rh(III) complexes of organochalcogen (S/Se/Te) ligands were synthesized and along with a co-catalyst Cu(OAc)2, used for the base/solvent free catalysis of Buchwald type C–N coupling of amines and aryl chlorides under aerobic conditions.
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Photocatalytic xanthate-based radical addition/cyclization reaction sequence toward 2-biphenyl isocyanides: synthesis of 6-alkylated phenanthridines

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00136H, Communication
Pedro López-Mendoza, Luis D. Miranda
A photocatalytic xanthate-based radical addition/cyclization reaction cascade toward 2-biphenylisocyanides is described as a practical and modular approach to 6-alkylated phenanthridines.
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Study on the ArI-catalyzed intramolecular oxy-cyclization of 2-alkenylbenzamides to benzoiminolactones

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00612B, Communication
Huixia Liu, Xiaojun Deng, Xie Huang, Nan Ji, Wei He
A metal-free synthetic method toward the preparation of benzoiminolactones through oxy-cyclization of 2-alkenylbenzamides mediated by a catalyst/oxidant (ArI/mCPBA) system was developed.
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Ni(II)-Catalyzed vinylic C–H functionalization of 2-acetamido-3-arylacrylates to access isotetronic acids

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00557F, Paper
Biswajit Roy, Eshani Das, Avijit Roy, Dipakranjan Mal
A ligand-free Ni(II)-catalyzed cascade annulation reaction for the synthesis of 4-aryl-substituted isotetronic acids from 2-acetamido-3-arylacrylates via vinylic C–H functionalization is reported.
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Asymmetric trehalose analogues to probe disaccharide processing pathways in mycobacteria

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00253D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Hadyn L. Parker, Ruben M. F. Tomás, Christopher M. Furze, Collette S. Guy, Elizabeth Fullam
Chemoenzymatic synthesis of azido-functionalised asymmetric trehalose analogues that are resistant to enzymatic degradation to probe carbohydrate processing pathways in mycobacteria.
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The key entity of a DCAR agonist, phosphatidylinositol mannoside Ac1PIM1: its synthesis and immunomodulatory function

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/C9OB02724F, Communication
Yohei Arai, Shota Torigoe, Takanori Matsumaru, Sho Yamasaki, Yukari Fujimoto
We achieved the first synthesis of phosphatidylinositol mannoside Ac1PIM1, and a very potent agonist of an innate immune receptor DCAR is demonstrated.
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Heterologous expression of the trichostatin gene cluster and functional characterization of N-methyltransferase TsnB8

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00617C, Communication
Wei Liu, Vinay Gopal Jannu, Zhiwen Liu, Qingbo Zhang, Xiaodong Jiang, Liang Ma, Wenjun Zhang, Changsheng Zhang, Yiguang Zhu
N-Methyltransferase TsnB8 was demonstrated to catalyze successive methyltransfer reactions in the biosynthesis of trichostatin.
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Discrimination of cellular developmental states focusing on glycan transformation and membrane dynamics by using BODIPY-tagged lactosyl ceramides

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00547A, Paper
Kenta Arai, Atsuko Ohtake, Shusaku Daikoku, Katsuhiko Suzuki, Yukishige Ito, Kazuya Kabayama, Koichi Fukase, Yoshimi Kanie, Osamu Kanie
Different cellular states were discriminated by analysing either the glycan transformation of exogenously introduced fluorescently tagged probe molecules or fluorescence recovery after photobleaching before conversion.
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Rhodium-Catalyzed ortho-Acrylation of Aryl Ketone O-Methyl Oximes with Cyclopropenones

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00064G, Communication
Yafeng Liu, Yuan Tian, Kexin Su, Xin Guo, Baohua Chen
An efficient Rh-catalyzed ortho-acrylation reaction for the synthesis of chalcones from O-methyl ketoximes and cyclopropenones via C–H bond activation has been described. This cross-coupling reaction exhibits high functional group tolerance...
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Preparation of cage-shaped hexakis(spiroborate)s

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00518E, Paper
Hiroshi Danjo, Yuhki Masuda, Yuki Kidena, Masatoshi Kawahata, Kazuaki Ohara, Kentaro Yamaguchi
Direct construction of anionic hexakis(spiroborate) prismatic cages was realized by the reaction of hexahydroxytriphenylene, bis(dihydroxynaphthalene)s, and boric acid.
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