en Highly Z-selective synthesis of 1,3-oxathiol-2-ylidenes and 4-methylene-oxazolidine-2-thiones via atom-specific 5-exo-dig cyclization of propargyl alcohol with isothiocyanate By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00083C, PaperS. Antony Savarimuthu, D. G. Leo Prakash, S. Augustine Thomas, Thirumanavelan Gandhi, Mrinal K. BeraThe Z-selectivity observed in imine and alkene motifs after 5-exo-dig cyclization of propargyl alcohol and isothiocyanate is rare in the literature and this selectivity can be attributed to electronic and steric factors of the imine and alkene motif respectively.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Selenium-promoted electrophilic cyclization of arylpropiolamides: synthesis of 3-organoselenyl spiro[4,5]trienones By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00609B, PaperAna Maria S. Recchi, Pedro H. P. Rosa, Davi F. Back, Gilson ZeniA synthetic approach to regioselective synthesis of 3-organochalcogenyl spiro[4,5]trienones and 3-organochalcogenyl[4,5]triene-2,6-diones is described through the reaction of arylpropiolamides with an electrophilic chalcogen source.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Proof of concept for poor inhibitor binding and efficient formation of covalent adducts of KRASG12C and ARS compounds By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3069-3081DOI: 10.1039/D0OB00071J, PaperMaria G. Khrenova, Anna M. Kulakova, Alexander V. NemukhinComprehensive molecular modeling and kinetic analysis reveal a novel mechanism of the inhibition of the oncogenic mutant of the “undruggable” KRAS protein.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en A modular approach to the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3047-3068DOI: 10.1039/D0OB00078G, PaperRamona Schütz, Maximilian Meixner, Iris Antes, Franz BracherA modular short-step synthesis of the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine was developed employing N-acyl-Pictet–Spengler reaction and Ullman diaryl ether synthesis as central steps.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Diversity oriented multi-component reaction (DOS–MCR) approach to access natural product analogues: regio- and chemo-selective synthesis of polyheterocyclic scaffolds via one-pot cascade reactions By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3082-3092DOI: 10.1039/D0OB00368A, PaperLakshmanan Palanivel, Vasuki GnanasambandamSkeletally diverse and complex polyheterocyclic hybrid scaffolds have been accessed via one-pot three-component reaction by exploiting the build/couple/pair strategy of diversity oriented synthesis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Recent progress in (hetero)arene cation radical-based heteroarene modification By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,2975-2990DOI: 10.1039/D0OB00441C, Research ArticleHai-Lei CuiThis review summarizes the advances in heteroarene modification via transformations of in situ generated (hetero)arene cation radicals, ranging from 2010 to 2020.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Stereoselective preparation of P,axial-stereogenic allenyl bisphosphine oxides via chirality-transfer By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3017-3021DOI: 10.1039/D0OB00390E, CommunicationMao-Ran Qiu, Hong-Xing Zheng, Jing-Jing Ye, Bing-Xia Yan, Chang-Qiu Zhao, Qiang LiAllenyl bisphosphine oxides having variable chirality were prepared in high dr, which was controlled by chiral carbon and phorphorus.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Regio- and stereoselective synthesis of 1,4-enynes by iron-catalysed Suzuki–Miyaura coupling of propargyl electrophiles under ligand-free conditions By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3022-3026DOI: 10.1039/D0OB00357C, CommunicationRyosuke Agata, Siming Lu, Hiroshi Matsuda, Katsuhiro Isozaki, Masaharu NakamuraThe first iron-catalysed cross coupling of propargyl electrophiles with lithium alkenylborates has been developed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Photochemical rearrangement of diarylethenes: synthesis of functionalized phenanthrenes By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3098-3103DOI: 10.1039/D0OB00296H, PaperA. V. Zakharov, A. V. Yadykov, A. G. Lvov, E. A. Mitina, V. Z. ShirinianThe photocyclization of diarylethenes bearing naphthalene units was explored and a convenient protocol for the synthesis of functionalized phenanthrenes was proposed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en The ruthenium(II)-catalyzed C–H olefination of indoles with alkynes: the facile construction of tetrasubstituted alkenes under aqueous conditions By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3158-3163DOI: 10.1039/D0OB00508H, PaperMing Li, Tian-Yu Yao, Sheng-Zheng Sun, Ting-Xun Yan, Li-Rong Wen, Lin-Bao ZhangAn environmentally-friendly and facile protocol for the construction of tetrasubstituted alkenes has been established with Ru(II)-catalyzed C–H bond functionalizations under mild conditions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Catalyst and solvent switched divergent C–H functionalization: oxidative annulation of N-aryl substituted quinazolin-4-amine with alkynes By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3032-3037DOI: 10.1039/D0OB00318B, CommunicationSiddi Ramulu Meesa, Praveen Kumar Naikawadi, Kishan Gugulothu, K. Shiva KumarCatalyst and solvent controlled ortho/peri site-selective oxidative annulation of C–H bonds of N-aryl substituted quinazolin-4-amines with internal alkynes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Progress in recent development of stereoselective synthesis of β2-amino acid derivatives from β-nitroacrylate derivatives By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,2991-3006DOI: 10.1039/D0OB00448K, Review ArticleHao-Wei Zeng, Ping-Yu Wu, Hsyueh-Liang Wuβ2-Amino acids: recent advances in the synthesis of β2-amino acids and their derivatives from various stereoselective transformations of β-nitroacrylates are summarized.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Construction of pH sensitive smart glutathione peroxidase (GPx) mimics based on pH responsive pseudorotaxanes By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3125-3134DOI: 10.1039/D0OB00122H, PaperJiaxi Li, Wenlong Jia, Ganghui Ma, Xiaoyin Zhang, Shaojie An, Tao Wang, Shan ShiTwo pH-sensitive smart glutathione peroxidase (GPx) mimics were developed by using pH-responsive pseudorotaxanes based on cucurbit[6]uril and organoselenium compounds.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en C-Glycosylation enabled by N-(glycosyloxy)acetamides By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3043-3046DOI: 10.1039/D0OB00561D, CommunicationMiao Liu, Bo-Han Li, Tian Li, Xia Wu, Meng Liu, De-Cai Xiong, Xin-Shan YeAn effective C-glycosylation protocol using N-(glycosyloxy)acetamides as donors promoted by SnBr4 has been developed, delivering alkyl C-glycosides and aryl-β-C-glycosides in high yields.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Enantioselective synthesis of chiral α-alkynylated thiazolidones by tandem S-addition/acetalization of alkynyl imines By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3117-3124DOI: 10.1039/D0OB00365D, PaperMei-Xin Wang, Juan Liu, Zhen Liu, Yingcheng Wang, Qi-Qiong Yang, Wenyu Shan, Yu-Hua Deng, Zhihui ShaoA SPINOL-CPA catalyzed asymmetric [2 + 3]-annulation of in situ generated alkynyl imines and 1,4-dithiane-2,5-diol has been developed to afford enantiopure α-alkynylated thiazolidones.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Asymmetric synthesis of (−)-solanidine and (−)-tomatidenol By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3169-3176DOI: 10.1039/D0OB00457J, PaperYun Wang, Guanxin Huang, Yong Shi, Wei-sheng Tian, Chunlin Zhuang, Fen-Er ChenThe asymmetric synthesis of (−)-solanidine (1) and (−)-tomatidenol (2) has been achieved by employing a cascade ringswitching reaction and a cascade azide reduction/intramolecular reductive amination with 32% and 18.7% overall yields respectively.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Experimental results and computational insight into sequential reactions of β-(2-aminophenyl)-α,β-ynones with aryl isocyanates/benzoyl isothiocyanate By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3177-3189DOI: 10.1039/D0OB00087F, PaperAntonio Arcadi, Massimiliano Aschi, Marco Chiarini, Fabio Marinelli, Vincenzo Marsicano, Gustavo PortaloneThe selective formation of quinazoline vs. benzoxazine and benzothiazine derivatives from β-(2-aminophenyl)-α,β-ynones and aryl isocyanates/benzoyl isothiocyanate was explored. DFT calculations provide a plausible rationale.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Construction of 2,3-disubstituted benzo[b]thieno[2,3-d]thiophenes and benzo[4,5]selenopheno[3,2-b]thiophenes using the Fiesselmann thiophene synthesis By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3164-3168DOI: 10.1039/D0OB00300J, PaperRoman A. Irgashev, Nadezhda S. Demina, Gennady L. RusinovA number of 2,3-disubstituted benzo[b]thieno[2,3-d]thiophenes and benzo[4,5]selenopheno[3,2-b]thiophenes have been obtained using a convenient approach based on the Fiesselmann thiophene synthesis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Pseudo-enantiomeric carbohydrate-based N-heterocyclic carbenes as promising chiral ligands for enantiotopic discrimination By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3012-3016DOI: 10.1039/D0OB00155D, CommunicationAlexander S. Henderson, John F. Bower, M. Carmen GalanThe practical synthesis of pseudo-enantiomeric carbohydrate-based NHC–Rh complexes bearing C1 or C3 sterically differentiated positions is reported. We show that steric bulk at either C1 or C3 leads to enantiotopic discrimination in the hydrosilylation of acetophenone.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Synthesis and aggregation behaviour of single-chain, 1,32-alkyl-branched bis(phosphocholines) – part 2: lateral chain length triggers self-assembling from sheets to fibres to vesicles By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00534G, PaperKai Gruhle, Max Tuchtenhagen, Sindy Müller, Gerd Hause, Annette Meister, Simon DrescherThe synthesis of six single-chain, alkyl-branched bolalipids and first investigations of the lyotropic behaviour of these lipids are reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Synthesis of disaccharide modified berberine derivatives and their anti-diabetic investigation in zebrafish using a fluorescence-based technology By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00327A, PaperLizhen Wang, Haotian Kong, Meng Jin, Xiaobin Li, Rostyslav Stoika, Houwen Lin, Kechun LiuDiglucose modified berberine derivatives can dramatically promote the uptake of 2-NBDG in both zebrafish larvae and their eyes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Copper-catalyzed diastereoselective hydrothioetherification of oxa(aza)benzonorbornadienes By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00659A, PaperQifu Lin, Yongqi Yao, Wen Yang, Yun Tan, Shuqi Chen, Donghan Chen, Dingqiao YangA novel copper-catalyzed multicomponent one-pot syn-selective hydrothioetherification of oxa(aza)bicyclic alkenes to synthesize unsymmetrical thioethers has been established.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Half-sandwich (η5-Cp*)Rh(III) complexes of pyrazolated organo-sulfur/selenium/tellurium ligands: efficient catalysts for base/solvent free C–N coupling of chloroarenes under aerobic conditions By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00538J, PaperCharu Sharma, Avinash Kumar Srivastava, Kamal Nayan Sharma, Raj Kumar JoshiThree new Rh(III) complexes of organochalcogen (S/Se/Te) ligands were synthesized and along with a co-catalyst Cu(OAc)2, used for the base/solvent free catalysis of Buchwald type C–N coupling of amines and aryl chlorides under aerobic conditions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Photocatalytic xanthate-based radical addition/cyclization reaction sequence toward 2-biphenyl isocyanides: synthesis of 6-alkylated phenanthridines By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00136H, CommunicationPedro López-Mendoza, Luis D. MirandaA photocatalytic xanthate-based radical addition/cyclization reaction cascade toward 2-biphenylisocyanides is described as a practical and modular approach to 6-alkylated phenanthridines.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Study on the ArI-catalyzed intramolecular oxy-cyclization of 2-alkenylbenzamides to benzoiminolactones By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00612B, CommunicationHuixia Liu, Xiaojun Deng, Xie Huang, Nan Ji, Wei HeA metal-free synthetic method toward the preparation of benzoiminolactones through oxy-cyclization of 2-alkenylbenzamides mediated by a catalyst/oxidant (ArI/mCPBA) system was developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Electrochemical synthesis of selenyl-dihydrofurans via anodic selenofunctionalization of allyl-naphthol/phenol derivatives and their anti-Alzheimer activity By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00629G, CommunicationMarcos R. Scheide, Alex R. Schneider, Guilherme A. M. Jardim, Guilherme M. Martins, Daniele C. Durigon, Sumbal Saba, Jamal Rafique, Antonio L. BragaHerein, we report an eco-friendly, electrosynthetic approach for the intramolecular oxyselenylation of allyl-naphthol/phenol derivatives.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en N-Hydroxy peptides: solid-phase synthesis and β-sheet propensity By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00664E, PaperMatthew P. Sarnowski, Juan R. Del ValleBackbone amide hydroxylation of peptide strands enhances β-hairpin folding.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Acylation of oxindoles using methyl/phenyl esters via mixed Claisen condensation – An access to 3-alkylideneoxindoles By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Accepted ManuscriptDOI: 10.1039/D0OB00789G, CommunicationRamdas Sreedharan, Purushothaman Rajeshwaran, Pradeep Kumar Reddy Panyam, Saurabh Yadav, C. M. Nagaraja, THIRUMANAVELAN GANDHIPredominantly, aggressive acid chlorides and stoichiometric coupling reagents are employed in the acylating process for synthesizing carbonyl tethered heterocycles. Herein, we report simple acyl sources, viz. methyl and phenyl esters...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en The key entity of a DCAR agonist, phosphatidylinositol mannoside Ac1PIM1: its synthesis and immunomodulatory function By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/C9OB02724F, CommunicationYohei Arai, Shota Torigoe, Takanori Matsumaru, Sho Yamasaki, Yukari FujimotoWe achieved the first synthesis of phosphatidylinositol mannoside Ac1PIM1, and a very potent agonist of an innate immune receptor DCAR is demonstrated.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Heterologous expression of the trichostatin gene cluster and functional characterization of N-methyltransferase TsnB8 By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00617C, CommunicationWei Liu, Vinay Gopal Jannu, Zhiwen Liu, Qingbo Zhang, Xiaodong Jiang, Liang Ma, Wenjun Zhang, Changsheng Zhang, Yiguang ZhuN-Methyltransferase TsnB8 was demonstrated to catalyze successive methyltransfer reactions in the biosynthesis of trichostatin.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Donor–acceptor fluorophores as efficient energy transfer photocatalysts for [2 + 2] photodimerization By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/C9OB02735A, PaperQing-An Wu, Feng Chen, Chen-Chao Ren, Xue-Fen Liu, Hao Chen, Liang-Xuan Xu, Xiao-Cong Yu, Shu-Ping LuoDonor–acceptor fluorophores can act as efficient energy transfer photocatalysts to activate enone substrates, realizing photodimerization and isomerization reaction of enone substrates without precious metal photocatalysts.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Catalyst- and Solvent-Free Efficient Access to N-Alkylated Amines via Reductive Amination using HBPin By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Accepted ManuscriptDOI: 10.1039/D0OB00740D, CommunicationARNAB RIT, Vipin Kumar Pandey, Somnath BauriA sustainable approach which works under catalyst- and solvent-free conditions for the synthesis of structurally diverse secondary amines has been uncovered. This one-pot protocol works efficiently at room temperature and...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en A silver-catalyzed radical ring-opening reaction of cyclopropanols with sulfonyl oxime ethers By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00055H, PaperXiaobao Zeng, Xin Wang, Yanan Zhang, Li Zhu, Yu ZhaoA simple and efficient method for the radical ring-opening reaction of cyclopropanols with sulfonyl oxime ethers catalyzed by AgNO3 is developed, affording γ-keto oxime ethers in moderate to good yields.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Discrimination of cellular developmental states focusing on glycan transformation and membrane dynamics by using BODIPY-tagged lactosyl ceramides By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00547A, PaperKenta Arai, Atsuko Ohtake, Shusaku Daikoku, Katsuhiko Suzuki, Yukishige Ito, Kazuya Kabayama, Koichi Fukase, Yoshimi Kanie, Osamu KanieDifferent cellular states were discriminated by analysing either the glycan transformation of exogenously introduced fluorescently tagged probe molecules or fluorescence recovery after photobleaching before conversion.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Rhodium-Catalyzed ortho-Acrylation of Aryl Ketone O-Methyl Oximes with Cyclopropenones By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Accepted ManuscriptDOI: 10.1039/D0OB00064G, CommunicationYafeng Liu, Yuan Tian, Kexin Su, Xin Guo, Baohua ChenAn efficient Rh-catalyzed ortho-acrylation reaction for the synthesis of chalcones from O-methyl ketoximes and cyclopropenones via C–H bond activation has been described. This cross-coupling reaction exhibits high functional group tolerance...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Recent Progress on Transition Metal-catalysed Regioselective C–H Transformations Based on Noncovalent Interactions By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Accepted ManuscriptDOI: 10.1039/D0OB00703J, Review ArticleYoichiro Kuninobu, Takeru TorigoeTransition metal-catalysed C–H transformations are powerful tools to obtain functionalised organic molecules from simple starting materials. To control regioselectivity is one of the most important issues in C–H transformations. Since...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Divergent syntheses of okaramines C, J, L, and S-U By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Accepted ManuscriptDOI: 10.1039/D0OB00587H, CommunicationXiao Wan Li, Tong xu Si, Ya-Ping Liu, Mingzhong Wang, Albert S. C. ChanThe total synthesis of six novel okaramines (C, J, L, and S-U) was accomplished with a precise synthesis scheme involving few steps and with practical yield of 6.7%-23.0%. The significance...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Electrochemically enabled functionalization of indoles or anilines to synthesis of hexafluoroisopropoxy indole and anilinederivatives By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Accepted ManuscriptDOI: 10.1039/D0OB00157K, CommunicationZu-yu Mo, Xin-Yu Wang, Yu-zhen Zhang, Li Yang, Hai-Tao Tang, Ying-Ming PanAn environmentally benign electrochemically enabled site-selective functionalization of indole or aniline derivatives with hexafluoroisopropanol in the presence of tetrabutyl ammonium hexafluorophosphate as redox catalyst and electrolyte was demonstrated in this...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Synthesis of unsymmetrical benzils via palladium-catalysed α-arylation–oxidation of 2-hydroxyacetophenones with aryl bromides By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00575D, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Takanori Matsuda, Souta OyamaUnsymmetrical benzils are synthesised by a one-pot tandem palladium-catalysed α-arylation and oxidation of 2-hydroxyacetophenones with aryl bromides.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Copper(I)/Ganphos catalysis: enantioselective synthesis of diverse spirooxindoles using iminoesters and alkyl substituted methyleneindolinones By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00546K, PaperHao Cui, Ke Li, Yue Wang, Manman Song, Congcong Wang, Donghui Wei, Er-Qing Li, Zheng Duan, François MatheyA copper/Ganphos-catalyzed asymmetric 1,3-dipolar cycloaddition of glycine iminoesters with alkyl substituted 3-methylene-2-oxindoles is described, producing the spiro[pyrrolidin-3,3'-oxindole]s in good yields with high ee.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Blue emissive dimethylmethylene-bridged triphenylamine derivatives appending cross-linkable groups By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00622J, PaperKangyu Zhou, Hongfei Pan, Yongjie Zhang, Houchen Wang, Xiaofei Dong, Xiangkui Ren, Xianggao Li, Shirong Wang, Zhijian ChenBlue-emissive and cross-linkable dimethylmethylene-bridged triphenylamine derivatives were synthesized and their optical and electrochemical properties were investigated.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Origin of the ligand effect in the cobalt catalyzed regioselective hydroboration of 1,3-diene By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00628A, PaperYuhua Liu, ZhongJie Jiang, Jipei ChenThe detailed mechanism and the origin of the ligand-controlled regioselectivity in the cobalt catalyzed hydroboration of 2-substituted 1,3-diene have been investigated.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Enantioselective Synthesis of Indanone Spiro-Isochromanone Derivatives via Dinuclear Zinc-Catalyzed Michael/Transesterification Tandem Reaction By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Accepted ManuscriptDOI: 10.1039/D0OB00541J, PaperXiao-Chao Yang, Meng Xu, Jin-Bao Wang, Meng-Meng Liu, Francois Mathey, Yuan-Zhao Hua, Mincan WangAn enantioselective Michael/transesterification tandem reaction of α-hydroxy indanones with ortho-ester chalcones was realized by dinuclear zinc catalysts. A series of enantiomerically pure spiro[indanone-2,3’-isochromane-1-one] derivatives were obtained in good yields with...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Synthesis and photophysical properties of selenopheno[2,3-b]quinoxaline and selenopheno[2,3-b]pyrazine heteroacenes By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Accepted ManuscriptDOI: 10.1039/D0OB00718H, PaperAmol Sonawane, Atsushi Shimozuma, Taro Udagawa, Masayuki Ninomiya, Mamoru KoketsuIn this paper, we report the novel synthesis of three different heterocycles namely 2-arylselenopheno[2,3-b]quinoxaline, 3-(aryl/alkylselanyl)-2-arylselenopheno[2,3-b]quinoxaline and 6-phenyl-7-(arylselanyl)selenopheno[2,3-b]pyrazine derivatives from the corresponding 2,3-dichloroquinoxaline and 2,3-dichloropyrazine derivatives. Further, photophysical properties were investigated...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Recent advances in β-L-rhamnosylation By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3216-3228DOI: 10.1039/D0OB00297F, Review ArticleDiksha Rai, Suvarn S. KulkarniThis review describes various methodologies for the stereoselective 1,2-cis glycosylation of L-rhamnose leading to β-L-rhamnosides and their applications in oligosaccharide synthesis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Synthesis, structures and photophysical properties of hexacoordinated organosilicon compounds with 2-(2-pyridyl)phenyl groups By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3239-3242DOI: 10.1039/D0OB00484G, CommunicationShohei Furuta, Toshiaki Mori, Yusuke Yoshigoe, Kohei Sekine, Yoichiro KuninobuWe synthesised novel air-, water-, heat-, acid-, and base-stable hexacoordinated organosilicon compounds, which contain two C,N-bidentate ligands and form two silafluorene equivalent moieties, with Lewis acid–base interactions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Three-component synthesis of 1,4-benzothiazines via iodide-catalyzed aerobic C–H sulfuration with elemental sulfur By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3234-3238DOI: 10.1039/D0OB00074D, CommunicationJingjing Jiang, Xiaolong Tuo, Zhuquan Fu, Huawen Huang, Guo-Jun DengFive to Six: Beyond the well-established thiazole formation from elemental sulfur, this method provides the first access to the corresponding six-membered N,S-heterocyclic products via direct functionalization of multiple C–H bonds.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Phenylboronic acid-catalyzed tandem construction of S–S and C–S bonds: a new method for the synthesis of benzyl disulfanylsulfone derivatives from S-benzyl thiosulfonates By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3243-3248DOI: 10.1039/D0OB00442A, CommunicationRaju Jannapu Reddy, Md. Waheed, Gamidi Rama KrishnaA novel and unique phenylboronic acid-catalyzed tandem construction of S–S and C–S bonds via dimerization–sulfonylation has been disclosed for the synthesis of benzyl disulfanylsulfone derivatives.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en The quasi-irreversible inactivation of cytochrome P450 enzymes by paroxetine: a computational approach By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3334-3345DOI: 10.1039/D0OB00529K, PaperEmadeldin M. Kamel, Al Mokhtar LamsabhiThe potency of paroxetine as a P450 inhibitor is mainly attributed to the availability of two active sites on its structure, its compatibility with P450's active site and the ease of its tight coordination to heme iron.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
en Direct recognition and sensitive detection of circular RNA with ligation-based PCR By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, 18,3269-3273DOI: 10.1039/D0OB00625D, CommunicationPengbo Zhang, Na Guo, Kejian Gao, Fengxia Su, Fangfang Wang, Zhengping LiA sensitive and specific method for circRNA detection is developed through the direct ligation of two ingeniously designed DNA probes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
