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Cell-specific spatial profiling of targeted protein expression to characterize the impact of intracortical microelectrode implantation on neuronal health

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01628A, Paper
Open Access
Lindsey N. Druschel, Niveda M. Kasthuri, Sydney S. Song, Jaime J. Wang, Allison Hess-Dunning, E. Ricky Chan, Jeffrey R. Capadona
Multiplex immunochemistry for proteins examining neuronal structure or function in NeuN+ regions adjacent intracortical microelectrodes (MEA) more closely matched historic intracortical MEA recording performance than traditional IHC quantification.
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Porous helical supramolecular columns self-organized via the fluorophobic effect of a semifluorinated tapered dendron

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01951B, Paper
Open Access
Dipankar Sahoo, Mihai Peterca, Mohammad R. Imam, Devendra S. Maurya, Virgil Percec
Fluorophobic effect enhances supramolecular microsegregation.
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A biomimetic solution, albumin–doxorubicin molecular complex, targeting tumor and tumor-draining lymph nodes

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01917B, Paper
Rui Guo, Lanlan Zhong, Sirui Ma, Bokai Gong, Chen Shen, Zijun Wang, Li Deng, Dong Zhao, Huile Gao, Tao Gong
Chemotherapy-induced immunologic cell death is haunted by the non-specific distribution of chemotherapeutic drugs and insignificant immune activation effects, which render efforts to inhibit the distant metastasis of tumors frustrated.
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Chemically engineered exogenous organic reactions in living cells for in situ fluorescence imaging and biomedical applications

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01925C, Review Article
Gang Song, Zhiwen Yang, Yiming Huang, Haotian Bai, Fengting Lv, Shu Wang
Key intracellular in situ synthesis processes, including the synthesis of near-infrared fluorescent dyes, intracellular oxidative cross-linking, polymerization, and bioorthogonal reactions, as well as their biomedical applications were summarized.
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Intrafibrillar Calcium Carbonate Mineralization of Electrospinning Polyvinyl Alcohol/Collagen Films with Improved Mechanical and Bioactive Properties

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01472C, Paper
Yin Liu, Xin Gao, Yuqi Li, Anqi Gao, Zhuozhi Zheng, Jingjiang Wei, Hongye Yang, Hang Ping, Hao Xie, Hao Wang, Weiming Wang, Zhengyi Fu
Collagen films play an essential role in guided bone regeneration (GBR) techniques, which creat space, promote cell adhesion, and induce osteogenic differentiation. It is therefore crucial to design appropriate GBR...
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Long-term leaching kinetics and solution chemistry of aqueous BaTiO3 powder suspensions: a numerical model supported experiment

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01708K, Paper
Marcus Bentzen, Vojtěch Lindauer, Pavel Mokrý, Ragnhild Elizabeth Aune, Julia Glaum
The advent of lead-free perovskite materials with favorable toxicity profiles has made them candidates for in vivo and environmental applications.
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3D-printed biomimetic scaffolds loaded with ADSCs and BMP-2 for enhanced rotator cuff repair

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01073F, Paper
Zhonglian Wu, Jian Yang, Hui Chong, Xiaomei Dai, Haidi Sun, Junli Shi, Meijuan Yuan, Dianwei Liu, Mengbo Dang, Hang Yao, Wenyong Fei
The schematic diagram of a 3D-printed biomimetic scaffold applied to tendon–bone interface repair.
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Electronic band structure modulation for sonodynamic therapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01679C, Review Article
Yafang Shi, Chengzhilin Li, Linquan Li, Qingbin He, Qingyi Zhu, Ziang Xu, Yanzi Liu, Nianlei Zhang, Meng Zhang, Jianwei Jiao, Runxiao Zheng
Sonodynamic therapy (SDT) is a burgeoning and newfangled therapy modality with great application potential. Sonosensitizers are most essential factors to ensure the effectiveness of SDT. For the past few years,...
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A bilayer hydrogel mimicking the periosteum-bone structure for innervated bone regeneration

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11187-11201
DOI: 10.1039/D4TB01923G, Paper
Wenhui Lyu, Yuyue Zhang, Shaopei Ding, Xiang Li, Tong Sun, Jun Luo, Jian Wang, Jianshu Li, Lei Li
The bilayer hydrogel GS@Mg/GP@Mg in this study is a promising material to promote innervated bone regeneration for functional and structural repair of bone defects.
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A dual-functional photosensitizer for mitochondria-targeting photodynamic therapy and synchronous polarity monitoring

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11259-11264
DOI: 10.1039/D4TB01872A, Paper
Liu Yang, Shenglong Gan, Jie Zhang, Yin Jiang, Qingxin Chen, Hongyan Sun
A dual-functional photosensitizer was developed, exhibiting potent phototoxicity and sensitivity to polarity changes.
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A simple hydrogen peroxide-activatable Bodipy for tumor imaging and type I/II photodynamic therapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11165-11171
DOI: 10.1039/D4TB01650E, Paper
Fangqing Ge, Yujie Sun, Yu Wang, Dan Yu, Zhijia Wang, Fabiao Yu, Bingran Yu, Hongbing Fu
A H2O2-activatable Bodipy with simultaneous type I and type II photosensitization was designed for tumor imaging and therapy.
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Drug-delivery and biological activity in colorectal cancer of a supramolecular porous material assembled from heptameric chromium-copper-adenine entities

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11156-11164
DOI: 10.1039/D4TB01521E, Paper
Sandra Mena-Gutiérrez, Ekain Maiza-Razkin, Jon Pascual-Colino, Marcos J. Araúzo-Bravo, Garikoitz Beobide, Oscar Castillo, Ainara Castellanos-Rubio, Daniela Gerovska, Antonio Luque, Sonia Pérez-Yáñez
Supramolecular metal-organic porous materials as drug delivery systems, modulation of the release kinetics using cholesterol as pore blocking agent and its impact on colorectal cancer cell cultures: cytotoxicity and RNA-seq transcriptomics studies.
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Nordihydroguaiaretic acid microparticles are effective in the treatment of osteoarthritis

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11172-11186
DOI: 10.1039/D4TB01342E, Paper
Kaamini M. Dhanabalan, Bhagyashree Padhan, Ameya A. Dravid, Smriti Agarwal, Nicholas M. Pancheri, Angela Lin, Nick J. Willet, Ashok Kumar Padmanabhan, Rachit Agarwal
Sustained delivery of NDGA via polymeric microparticles maintains therapeutic levels in joints, reduces cartilage damage, and alleviates post-traumatic osteoarthritis (PTOA) in mice through ROS modulation and autophagy induction.
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Microfluidic synthesis and accurate immobilization of low-density QD-encoded magnetic microbeads for multiplex immunoassay

By pubs.rsc.org
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J. Mater. Chem. B, 2024, 12,11230-11236
DOI: 10.1039/D4TB01585A, Paper
Zhou Sha, Tianyi Ling, Wenqi Yang, Haosu Xie, Chunnan Wang, Shuqing Sun
Accurate immobilization of microbeads in the gap of nickel patterns.
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Breakthrough in cancer therapy: lutetium texaphyrin–celecoxib conjugate for immune and photodynamic treatment

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB02019G, Highlight
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Qihang Ding, Yue Wang, Pengfei Zhang, Ling Mei
Kim et al. present a small-molecule photosensitizer, LuCXB, which combines a COX-2 inhibitor (celecoxib) with a near-infrared lutetium texaphyrin photocatalyst and was loaded CD133-aptamer functionalized exosome for cancer stem cells targeting.
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An innovative electrohydrodynamics-driven SERS platform for molecular stratification and treatment monitoring of lung cancer

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01434K, Highlight
Tuotuo Zhang, Biao Dong, Huiling Wang, Shuai Zhang
A schematic electrohydrodynamics-driven SERS platform to profile four proteins on sEVs to generate a unique molecular signature for lung cancer stratification.
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Nanomaterials and methods for cancer therapy: 2D materials, biomolecules, and molecular dynamics simulations

By pubs.rsc.org
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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01667J, Review Article
Welela M. Kedir, Lunna Li, Yaw Sing Tan, Natasa Bajalovic, Desmond K. Loke
Nanomaterials made from 2D semiconductors and biomolecules are reviewed. Cell-nanoparticle interactions are examined in recent simulations. These nanomaterials and MD simulations reveal novel mechanisms and enable cancer drug delivery and targeting.
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Enhanced Luminescence and Stability of TFMDSA Nanoparticles via Polymer-Induced aggregation for Bioimaging

By pubs.rsc.org
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J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01825G, Paper
Xiang Li, Xue Ren, Yuchao Luo, Haotian Shi, Zhigang Xie, Bin Xu, Wenjing Tian
In recent years, fluorescence imaging occupies a very important position in the life science and biomedical fields. However, achieving nanomaterials for bioimaging with both high fluorescence quantum efficiency and high...
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Extracellular matrix mimetic supramolecular hydrogels reinforced with covalent crosslinked mesoporous silica nanoparticles

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00499J, Paper
Open Access
Aygül Zengin, Shahzad Hafeez, Pamela Habibovic, Matthew Baker, Sabine van Rijt
Here we present a promising strategy to create hybrid, biomimetic supramolecular injectable hydrogels reinforced covalent crosslinked mesoporous silica nanoparticles for tissue engineering applications.
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Mitochondrial membrane potential-independent near-infrared fluorescent probes for viscosity-exclusive imaging

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01785D, Paper
Xiu Pan, Yu Zhao, Jia-Li Wang, Shun Feng, Xiao-Qi Yu, Ming-Yu Wu
A novel mitochondrial targeting mitochondrial membrane potential-independent near-infrared fluorescent probe, ACR-DMA, was developed which can be firmly immobilized in mitochondria for tracking of mitochondrial viscosity changes in vitro and in vivo.
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H2O2-activated mitochondria-targeting photosensitizer for fluorescence imaging-guided combination photodynamic and radiotherapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01653J, Paper
Qiufen Tian, Zifan Zhu, Yun Feng, Shirui Zhao, Hui Lin, Wen Zhang, Zhiai Xu
Radiotherapy is a primary modality in cancer treatment but accompanied by severe side effects to healthy tissues and radiation resistance to some extent. To overcome these limitations, we developed a...
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MnO2-mineralized milk exosomes as a novel nanoplatform for glutathione detection

By pubs.rsc.org
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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01662A, Paper
Xudong Wang, Xue Wu, Jiuheng Shen, Xian Zhao, Peifen Gao, Wantong Zhou, Wenlin An
This study introduces a novel nanoplatform by surface manganese dioxide (MnO2) mineralization of milk exosomes and labelling with curcumin, enhancing their utility in the detection of GSH.
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Illuminating cisplatin-induced ferroptosis in non-small-cell lung cancer with biothiol-activatable fluorescent/photoacoustic bimodal probes

By pubs.rsc.org
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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01656D, Paper
Li Xu, Hongwen Liu, Yi Kong, Lingyun Li, Jia Li, Kang Li, Shuzhi Liang, Bolin Chen
Using activatable NIR fluorescent/PA bimodal probes, we successfully monitored real-time biothiol changes during ferroptosis in NSCLC cells and tumors, revealing enhanced ferroptosis with the combined use of erastin and cisplatin.
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Bimetallic doped carbon dot nanozymes for enhanced sonodynamic and nanocatalytic therapy

By pubs.rsc.org
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J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01916D, Paper
Yandong Huang, Lanting Jia, Shiqi Zhang, Lan Yan, Lei Li
The conventional inorganic semiconductors are not suitable for acting as nanozymes or sonosensitizers for in vivo therapeutic nanomedicine owing to the lack of excellent biocompatibility. Biocompatible carbon dots (CDs) exhibit...
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NIR emissive probe for fluorescence turn-on based dead cell sorting and in vivo viscosity mapping in C. elegans

By pubs.rsc.org
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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01945H, Paper
Goraksha T. Sapkal, Farhan Anjum, Abdul Salam, Bodhidipra Mukherjee, Shilpa Chandra, Purabi Bala, Richa Garg, Shagun Sharma, Kush Kaushik, Chayan Kanti Nandi
An NIR emissive probe plays a pivotal role for in vitro and in vivo dead cell sorting.
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Micah Parsons insists he wasn't throwing "Mike McCarthy under the bus" with postgame comments

By sports.yahoo.com
Published On :: Wed, 13 Nov 2024 02:29:34 GMT

Cowboys edge rusher Micah Parsons pushed back against the perception he was taking a shot at coach Mike McCarthy in his postgame comments Sunday.


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Bigg Boss 12: 'I will not miss Deepak'

By www.rediff.com
Published On :: Mon, 05 Nov 2018 15:34:39 +0530

'I worked on my weaknesses like dressing up and putting on makeup. I started dancing. I guess that wasn't enough.'


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