The invention relates to antibody molecules having specificity for antigenic determinants of human OX40, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.

Provided are a support for affinity chromatography which has excellent alkali resistance, and a method for isolating immunoglobulin. A support for affinity chromatography, containing an immobilized protein ligand represented by the following formula (1): R—R2 (1) wherein R represents a polypeptide consisting of 4 to 30 amino acid residues that contains an amino acid sequence represented by ATK or ASK; and R2 represents a polypeptide consisting of 50 to 500 amino acid residues containing an immunoglobulin-binding domain consisting of an amino acid sequence represented by SEQ ID NO: 1 or SEQ ID NO: 2, the partial sequence thereof, or an amino acid sequence having 70% or more identity to these sequences; with the proviso that a terminus at which R2 binds to R is C-terminus or N-terminus of the immunoglobulin-binding domain.

Monitoring user activity on a mobile device is described. In one aspect, video content is received and played to a user of the mobile device. The monitoring activity detects an interruption of playback of the video content and determines an event associated with the interruption. The event is stored in the mobile device and communicated to a remote device.

An exemplary method includes a media service provider system 1) providing an end user of an integrated media service with access to a media program by way of a plurality of different media distribution models, 2) maintaining a catalog that includes comprehensive information about the media program, the comprehensive information being an aggregate of non-redundant information about the media program obtained from a plurality of independent source catalogs corresponding to the plurality of different media distribution models, and 3) providing, based on the comprehensive information included in the catalog, a media service user interface that supports discovery of the comprehensive information about the media program regardless of a user interface context from which a user request for information about the media program is received. Corresponding systems and methods are also described.

Aspects of a method and system for data processing in a device with integrated set-top-box and femtocell functionality are provided. Data may be received via an integrated femtocell and set-top-box device and may be synchronously processed, utilizing a common clock, to perform one or more femtocell functions and/or set-top-box functions. The common clock may be derived from global navigation satellite system signals. The integrated femtocell and set-top-box device may convert the received data from a first to a second format. The converted data may be transmitted to a cellular enabled communication device via a cellular transmitter within said integrated femtocell and set-top-box device and/or to a multimedia device via a multimedia interface within said integrated femtocell and set-top-box device. The received data may comprise multimedia content. The integrated femtocell and set-top-box device may be operable to encode, decode, transcode, encrypt, decrypt, scramble, descramble, and present the received multimedia content.

Provided is an adhesive composition for a protective film including an acrylic emulsion resin capable of providing contamination resistance on the film and low peel strength and minimizing generation of static electricity during peeling of the protective film. The acrylic emulsion resin includes a mixture including 80 to 99.9% by weight of a polymer of a (meth)acrylic acid ester monomer including a C1-C14 alkyl group and a (meth)acrylic acid ester monomer including an alkylene oxide unit, and 0.1 to 20% by weight of a monomer including a carboxyl group and/or a hydroxyl group or a combination thereof, and 5 to 30 parts by weight of a reactive emulsifier having a double bond structure radical-polymerizable with the polymer and including an alkylene oxide unit based on 100 parts by weight of the mixture.

Disclosed is a hot-dip galvanized steel sheet or an alloyed hot-dip galvanized steel sheet, which has a tensile strength of 980 MPa or more, excellent workability, high yield ratio and high strength. The hot-dip galvanized steel sheet or the alloyed hot-dip galvanized steel sheet is characterized by containing 0.12-0.3% by mass of C, 0.1% by mass or less (excluding 0% by mass) of Si, 2.0-3.5% by mass of Mn, 0.05% by mass or less (excluding 0% by mass) of P, 0.05% by mass or less (excluding 0% by mass) of S, 0.005-0.1% by mass of Al and 0.015% by mass or less (excluding 0% by mass) of N, with the balance made up of iron and unavoidable impurities. The hot-dip galvanized steel sheet or the alloyed hot-dip galvanized steel sheet is also characterized in that the metallic structure thereof contains bainite as a matrix structure, and the area ratio of ferrite is 3-20% and the area ratio of martensite is 10-35% relative to the entire structure.

Peptides having a structure characterized by the presence of two loops constrained in cyclic structure by the presence of covalent bonds between amino acid side chains, the amino acid sequences of the first and the second loop being substantially homologues to that of loop 1 (residues 29-38) and of loop 4 (residues 92-97) of NGF, respectively, displaying nerve growth factor (NGF) agonist or partial agonist activity.

The present invention relates to the identification and selection of attachment molecules that attach/immobilize an entity having a detectable activity or property on a support in an orientation that provides a detectable activity or property, and to surfaces made of the attachment molecules.

The present invention relates to methods for producing a polypeptide having biological activity, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first polynucleotide encoding the polypeptide operably linked to a second polynucleotide encoding a variant signal peptide or a variant prepropeptide; and (b) isolating the secreted polypeptide having biological activity from the cultivation medium.

The present invention provides variable mass labeling reagents, a set of the variable mass labeling reagents, and a multiplexed set of variable mass labeling reagents.

In one embodiment an enclosure for a high-density storage system, comprises a backplane to which a plurality of data storage devices may be coupled, a front panel opposite the backplane and defining a first airflow channel adjacent a front side of the data storage devices, a back panel opposite the front panel and comprising a second airflow channel adjacent the backplane, a floor panel and a top panel, a first side panel comprising an array of air flow inlets, a second side panel comprising at least one air flow outlet, and a fan assembly to expel air from the at least one air outlet.

Provided is an optical disc drive that may discharge static electricity externally. The optical disc drive may include a step motor that is configured to move an optical pickup back and forth and a cover disposed below the optical pickup. In one aspect, the cover includes an electrostatic discharge mechanism for moving static electricity generated on the step motor through the cover.

A food source information transferring system for a livestock meat-packing facility and a related method are disclosed. In one embodiment, the food source information transferring system is capable of reading tag-identifying information in a hook RFID tag incorporated in a hook that can be hung on a hook machine. An animal carcass attached to the hook then undergoes meat chopping, cutting, and/or packing operations in the meat-packing facility. For each meat package produced, a data set associated with the tag-identifying information in the hook RFID tag can be paired with a data set associated with a meat package label attached to the meat package. This dynamic and robust data association between the hook RFID tag and the meat package label enables a food source information database in the food source information transferring system to preserve and trace detailed food source information at various levels of meat production and processing.

A conveying apparatus has a conveying path to supply a plurality of products for consumption having soft parts and intended for processing to a processing device. A conveying intermediate space has conveying surfaces that face one another and receive the products for consumption between them while applying pressure thereto. A first conveying surface comprises a flexible surface-deformable conveying cover and a row arrangement of pressure elements that are arranged next to one another in a row extending transverse to the conveying direction, each having a pressure-applying transverse profile extending transverse to the conveying direction, and are held to be displaceable in the height dimension direction of the conveying intermediate space against a restoring force such that each pressure element co-operates with the surface-deformable conveying cover during the passage of the products for consumption through the conveying path in order to form a variable conveyor cross-section.

The present disclosure provides a cable-type secondary battery, comprising: an inner electrode; and a sheet-form laminate of separation layer-outer electrode, spirally wound to surround the outer surface of the inner electrode, the laminate being formed by carrying out compression for the integration of a separation layer for preventing a short circuit, and an outer electrode. According to the present disclosure, the electrodes and the separation layer are compressed and integrated to minimize ununiform spaces between the separation layer and the outer electrode and reduce the thickness of a battery to be prepared, thereby decreasing resistance and improving ionic conductivity within the battery. Also, the separation layer coming into contact with the electrodes absorbs an electrolyte solution to induce the uniform supply of the electrolyte solution into the outer electrode active material layer, thereby enhancing the stability and performances of the cable-type secondary battery.

In a cap assembly and a rectangular type secondary battery having the cap assembly, the cap assembly includes a cap plate made of a metallic or nonmetallic material, a hollow, low-melting point glass metal tube inserted into a hole formed in the cap plate, and a metallic or nonmetallic pin inserted into the hollow glass metal tube, wherein the cap plate, the glass metal tube and the pin are atomically bonded with one another at their contact areas by high-temperature heating.

Disclosed are sets of ink components, and ink compositions, useful for printing markings, on security documents, that are relatively resistant to counterfeiting. Also disclosed are the security documents formed, a method of printing and a method of authenticating the printed material. The markings, formed of the ink compositions have a spectral response that deviates from a predicted spectral response when linearly additively combining spectral responses of components of the ink composition, so that it becomes difficult to reverse-engineer the ink composition from the markings. Use of plural different markings, with each marking being a microdot, increases difficulty in counterfeiting. By forming a template of spectral responses of the original pattern, spectral responses of a pattern on an unknown document can be compared to the spectral responses on the template for determining whether the unknown document is authentic. Formation of the markings is facilitated using an inkjet printer.

A hard laminate sheet for security booklets and method of making the same. The laminate sheet comprises at least two hard core layers (e.g. of polycarbonate) and a flexible component (e.g. nylon) there between and extending beyond an outer edge of the core layers to form a flexible band. The flexible component may be provided as an intermediate layer also comprising a hard component (e.g. of polycarbonate) juxtaposed with the flexible component and laminated to the adjacent core layers. The flexible component comprises a plurality of apertures within which material of the adjacent core layers is laminated together and affixes the flexible component to the laminate sheet. Additional hard core layers may be laminated to the core layers which sandwich the intermediate layer. Optionally, the laminate sheet may be used for a travel document (such as a passport) and may be laser engraved. Also, optionally, the laminate sheet may comprise a hard core inlay layer configured for containing a contactless integrated circuit chip and antenna or other electronic hardware.

Apparatus and method for secure transactions between gaming machines and portable devices are described. The secure transactions may include a transfer of an amount of an indicia of credit with a cash value from the portable device to the gaming machine or a transfer of an amount of an indicia of credit with a cash value from the gaming machine to the portable device. A logic device, separate from a master gaming controller on the gaming machine and placed in the gaming machine, may be operable to authenticate a portable device, such as a smart card, and authorize transactions involving transfers of indicia of credit between the portable device and the gaming machine. The logic device may be operable to send authentication information relating to the portable device to a remote host where a value amount of transactions involving the portable device authorized by the logic device may be higher when the logic device and the remote host authenticate the portable device as opposed to when the portable is only authenticated by the logic device.

In a friction drive transmission apparatus arranged to transmit power by a frictional transmission force between two roller units pressed against each other, there is provided a pressing force imparting means to increase and decrease a pressing force imparted to a roller pair to vary the frictional transmission force between both roller units smoothly at the time of a shift.

An inverted pendulum type vehicle (1) includes a propulsion unit (50) provided in a lower part of a vehicle body to actuate a main wheel (52), a drive unit (90, 130) provided in a vertically intermediate part thereof and a seat (200) provided in an upper part of the vehicle body. A battery case (251) is mounted in a part of the vehicle body above the main wheel and behind the drive unit. The battery case is provided with an opening (257) extending from an upper part thereof to a lower end of a rear part thereof. A lid (260) hinged to the battery case selectively covers the upper end of a battery (250) received in the battery case. The battery is retained in the battery case with the help of suitable engagement arrangements (262, 263, 270, 271, 273, 274).

A magnetic recording tape according to one embodiment includes at least about eight data bands, wherein each data band is defined between a pair of adjacent servo tracks, each pair of adjacent servo tracks defining only a single data band therebetween. One of the servo tracks has data encoded therein, the data including data for encryption. A magnetic recording tape according to another embodiment includes a plurality of servo tracks, each servo track comprising a series of magnetically defined bars. An average height of the bars is less than about 50 microns. About eight to about twenty six data bands are present on the tape. A tape supply cartridge according to various embodiments has a magnetic recording tape as described herein.

An improved system and method are disclosed for improving functionality in software applications. In one example, the method includes a mobile device having a network interface, a processor, and a memory configured to store a plurality of instructions. The instructions include instructions for a superblock application having instructions for a function block included therein. The function block is configured to provide functions that are accessible to the superblock application via an application programming interface (API). The functions are provided within the superblock application itself and are accessible within the superblock application without switching context to another application on the mobile device.

The present invention discloses method and system for performing security monitoring on file downloading, and a non-transitory computer-readable medium that stores instructions for performing security monitoring on file downloading. The method includes upon detecting a file downloading operation, performing security detection on a downloaded file to determine whether the downloaded file is secure; if the downloaded file is secure, determining whether a downloading tool adopted when the file is downloaded is instant messenger (IM) software; and if the adopted downloading tool is IM software, modifying a filename extension of the downloaded file to ensure that the downloaded file is capable of being directly opened or run.

A platform application and methods of operation that integrate both native and third-party modules into an integrated environment on an inmate computing device is disclosed. Third-party modules or systems are applications meant to operate independent from the platform application. Information is communicated between the platform application and third-party module or system to add audit, alarm and other functions across all modules or systems controlled by the platform software. The third-party module or system is audited to allow triggering of rules that cause remedial action to be taken. Triggers can be on actions not monitored by a particular third-party module or system.

A program (e.g., an operating system) is provided a warning that it has a grace period in which to perform a function, such as cleanup (e.g., complete, stop and/or move a dispatchable unit). The program is being warned, in one example, that it is losing access to its shared resources. For instance, in a virtual environment, a guest program is warned that it is about to lose its central processing unit resources, and therefore, it is to perform a function, such as cleanup.

A program (e.g., an operating system) is provided a warning that it has a grace period in which to perform a function, such as cleanup (e.g., complete, stop and/or move a dispatchable unit). The program is being warned, in one example, that it is losing access to its shared resources. For instance, in a virtual environment, a guest program is warned that it is about to lose its central processing unit resources, and therefore, it is to perform a function, such as cleanup.

A program (e.g., an operating system) is provided a warning that it has a grace period in which to perform a function, such as cleanup (e.g., complete, stop and/or move a dispatchable unit). The program is being warned, in one example, that it is losing access to its shared resources. For instance, in a virtual environment, a guest program is warned that it is about to lose its central processing unit resources, and therefore, it is to perform a function, such as cleanup.

A program (e.g., an operating system) is provided a warning that it has a grace period in which to perform a function, such as cleanup (e.g., complete, stop and/or move a dispatchable unit). The program is being warned, in one example, that it is losing access to its shared resources. For instance, in a virtual environment, a guest program is warned that it is about to lose its central processing unit resources, and therefore, it is to perform a function, such as cleanup.

A program (e.g., an operating system) is provided a warning that it has a grace period in which to perform a function, such as cleanup (e.g., complete, stop and/or move a dispatchable unit). The program is being warned, in one example, that it is losing access to its shared resources. For instance, in a virtual environment, a guest program is warned that it is about to lose its central processing unit resources, and therefore, it is to perform a function, such as cleanup.

A film comprising a polymer blend of: (a) 0.15 to 0.8 wt % of an LDPE having an MI of 0.1 to 0.6 dg/min; and(b) 99.2 to 99.85 wt % of an LLDPE produced with a single-site catalyst comprising a metallocene and having a haze (HZlldpe), dart impact (DIlldpe), MD-Tear (MDTlldpe), and a slice long chain branching index of at least 0.90 for any portion of the composition having a molecular weight of 100,000 or above,wherein the film has a haze (HZblend), a dart impact (DIblend), and an MD-Tear (MDTblend), and HZblend=a*HZlldpe, where a is 0.20 to 0.70; DIblend=b*DIlldpe, where b is 0.9 to 1.3; and MDTblend=c*MDTlldpe, where c is 0.8 to 1.1.

A magnetic particle-polymer hybrid material can include: a substance having a structure of Formula 1 or derivative or salt thereof:Z(Y-Triazole-CH2—X—CH2—(FP)n)m (Formula 1), wherein Z is a magnetic particle smaller than 1 mm; n and m are independently integers; Y includes a first linker having an alkyl and/or aryl linked to the magnetic particle; X is CH2 or a heteroatom; FP is a functionalized polymer having: a first structure derived from a first norbornene compound linked to the magnetic particle through the Y-Triazole-CH2—X—CH2 linker; and one or more monomeric units each including a second structure derived from a second norbornene compound, where one of the monomeric units is linked to the first structure through a saturated or unsaturated alkyl, each monomeric unit includes a functional group capable of binding with another substance.

Process for the preparation of etherified melamine/formaldehyde condensates, in which first a methylolation of melamine with a formaldehyde component in the molar ratio of from 1:6 to 1:15, preferably at a pH of >7, is carried out. This is followed by an etherification of the resulting hydroxymethylation intermediate in the presence of a C1-C20-alkyl, preferably of a C1-C6-alcohol, particularly preferably of a C1-C4-alcohol, at a pH of 9.5 being established before, during and/or after the distillation. According to the invention, a plurality of hydroxymethylation, etherification and distillation steps follow in order to achieve an etherified melamine/formaldehyde condensate which is distinguished by a high degree of hydroxymethylation, a high solids content and a low viscosity.

A method for preparing a catalyst system for heterogenous catalysis of an isobutylene polymerization reaction includes the steps of forming an alumina support in which the alumina support has pores formed therein, and reacting BF3/methanol catalyst complex with the alumina support. The ratio of methanol to BF3 in the catalyst complex ranges from 0.5 moles to 2 moles of methanol per mole of BF3. The alumina support is formed so as to have pores each having a diameter of greater than twenty nanometers. The alumina support can be in the form of beads or extrudates having a length significantly greater than a diameter. The extrudate can also have a tri-lobe configuration.

A road safety barrier having a plurality of ropes supported by posts rigidly mounted on or in the ground is described. Each rope is held in tension against the posts and supported in a notch or groove in a side of the posts. The ropes are released from a post and the post is not pulled from the ground when a vertical force is exerted on the rope. The ropes when weaved are tensioned against the posts and this gives use to a combined frictional resistance to displacement of the ropes relative to each post along the length of the safety barrier. The structure of at least some of the posts and/or their mounting with respect to the ground defines a minimum bending yield strength in a direction along the length of the barrier. This minimum bending yield strength is greater than the bending moment resulting from the combined frictional resistance forces acting on the post.

A vibratory compactor having a first compacting element having a variable vibratory mechanism that sets a modifiable compaction effort, a second compacting element, a first sensor configured to measure a first surface compactability associated with the first compacting element, a second sensor configured to measure a second surface compactability associated with the second compacting element and a control system. The control system is configured to receive the first surface compactability, receive the second surface compactability, determine a target compaction effort for the first compacting element based on the first surface compactability and the second surface compactability, and modify the variable vibratory mechanism to set the compaction effort at the target compaction effort.

An oral cavity cleaning device includes a stem having a mainly longitudinal extension and a pointed profile at a first end; a fluid channel enclosed within the stem and extending along such stem; a fluid reservoir operably connected to the second end of the stem to establish a hydraulic connection with the channel; and a tip having bristles and designed to be removably associated with the first end of the stem, the tip having a plurality of through holes for the passage of fluids from the channel to the area external to the tip, at the bristles.

A wireless communication device is configured for performing uplink transmission power control. The wireless communication device includes a processor and instructions stored in memory. The wireless communication device performs uplink transmission power control for multiple regulated frequency bands or component carriers. The wireless communication device determines a total transmission power for at least one component carrier and allocates transmission power to at least one antenna.

A touch sensitive screen mobile information apparatus having a wireless communication unit for wireless device discovery is herein disclosed. Close proximity wireless device discovery is enabled by wireless searching near distance via radio frequency field for a wireless device, receiving information from the wireless device over the near distance wireless communication, and storing the received information at the information apparatus for future wireless connections. Authentication or pairing of devices may be eliminated due to close proximity of the direct wireless device discovery. After wireless device discovery, the information apparatus and the wireless device may become locked or paired for subsequent wireless communication over any number of wireless communication protocols or standards (e.g., Bluetooth, IEEE 802.11, 2.4GHz) without the need to repeat wireless discovery or pairing. Examples of information apparatus include smart phones, digital camera, laptops, or information pads. Examples of wireless devices include televisions, audio output devices, or printers.

A saddle type vehicle provided with a headlight stay for permitting a harness laying operation to be easily carried out. A motorcycle is provided with the headlight stay which is supported on a head pipe and extends toward the vehicle front side from the head pipe. A headlight unit is attached to the headlight stay. The headlight stay includes a first stay extending forward from the head pipe, in a side view of the vehicle and a second stay which is supported in a cantilever manner by a front portion of the first stay and extends rearwardly and upwardly. The headlight unit is partly disposed on the front side of the second stay and is disposed so as to overlap with the first stay.

A combined multi-lumen central access catheter and an embolic filter, further comprising an imaging modality to facilitate intravascular imaging of the filter.

A combined multi-lumen central access catheter and an embolic filter, further comprising an imaging modality to facilitate intravascular imaging of the filter.

A forceps includes first and second jaw members and at least one handle movable between an open position and a closed position for moving the jaw members between a spaced-apart position and an approximated position. A ratchet mechanism includes first and second ratchet components configured to engage one another upon movement of the at least one handle to the closed position to retain the jaw members in the approximated position. A knife is selectively movable between a retracted position and an extended position, wherein the knife extends between the jaw members to cut tissue therebetween. A safety mechanism is configured to inhibit extension of the knife when the jaw members are disposed in the spaced-apart position. Movement of the ratchet components into engagement with one another to retain the jaw members in the approximated position disengages the safety mechanism, thereby permitting extension of the knife.

Disclosed herein are methods, compositions and tools for repairing articular surfaces repair materials and for repairing an articular surface. The articular surface repairs are customizable or highly selectable by patient and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty.

Disclosed herein are methods, compositions and tools for repairing articular surfaces repair materials and for repairing an articular surface. The articular surface repairs are customizable or highly selectable by patient and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty.

A data source may be configured to provide usage data including subscriber identifiers and associated information indicative of subscriber device locations and usage. A data warehouse server may be configured to perform operations including: decrypting subscriber identifiers included in usage data received from the data source using a two-way rolling key groups algorithm; re-encrypting the subscriber identifiers decrypted from the usage data to create secure encrypted identifiers using a one-way secured encryption algorithm; and correlating the subscriber identifiers in the decrypted usage data with the corresponding re-encrypted identifiers.

Computationally implemented methods and systems are described herein that are designed to, among other things, receiving a level-one encrypted output of a surveillance device; encrypting at least a part of the level-one encrypted output of the surveillance device with a level-two encryption key whose decryption key is inaccessible by a level-two encryption entity; and transmitting a level-two encrypted output of the surveillance device.

A method and authentication server provide a mobile key. According to the method, upon receipt of an authentication message (access authentication) that is transmitted when a subscriber logs on to the network, the authentication server extracts a subscriber identification contained in said message and generates a corresponding mobile key, which is stored together with the respective extracted subscriber identification. Upon subsequent receipt of a key request message (key request) that is transmitted when a subscriber registers, the authentication server extracts a mobile identification of the subscriber contained in said message and searches for an identical mobile identification, which can be derived in accordance with a configurable derivation function from a subscriber identification that is stored in the authentication server. Once a derived mobile identification that is identical or can be uniquely assigned to the extracted mobile identification has been found, the authentication server provides the stored corresponding mobile key that has been generated, to cryptographically protect the mobile signaling messages of the registered subscriber.

A machined ceramic article having an initial surface defect density and an initial surface roughness is provided. The machined ceramic article is heated to a temperature range between about 1000° C. and about 1800° C. at a ramping rate of about 0.1° C. per minute to about 20° C. per minute. The machined ceramic article is heat-treated in air atmosphere. The machined ceramic article is heat treated at one or more temperatures within the temperature range for a duration of up to about 24 hours. The machined ceramic article is then cooled at the ramping rate, wherein after the heat treatment the machined ceramic article has a reduced surface defect density and a reduced surface roughness.