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Compact lens-free imager using a thin-film transistor for long-term quantitative monitoring of stem cell culture and cardiomyocyte production

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00528G, Paper
Open Access
Taishi Kakizuka, Tohru Natsume, Takeharu Nagai
A novel compact lens-free imager achieved high-throughput long-term monitoring within an incubator, demonstrating the quantification of the confluency of human iPS cells, epithelial-to-mesenchymal transition, and cardiomyocyte beating dynamics.
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Self-actuated microfluidic chiplet for two-stage multiplex nucleic acid amplification assay

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00752B, Paper
Open Access
Felix Ansah, Marziyeh Hajialyani, Fatemeh Ahmadi, Yuming Gu, Ergün Alperay Tarım, Michael G. Mauk, Gordon A. Awandare, Haim H. Bau
Self-actuated chiplet for Penn-RAMP assay.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: Deciphering hepatoma cell resistance to tyrosine kinase inhibitors: insights from a Liver-on-a-Chip model unveiling tumor endothelial cell mechanisms

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC90093F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Madhu Shree Poddar, Yu-De Chu, Chau-Ting Yeh, Cheng-Hsien Liu
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The content of this RSS Feed (c) The Royal Society of Chemistry




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A gravity-driven tissue chip to study the efficacy and toxicity of cancer therapeutics

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00404C, Paper
Open Access
Pouria Rafsanjani Nejad, Astha Lamichhane, Prasiddha Guragain, Gary Luker, Hossein Tavana
A 96-well plate format, fully-automated multi-organ tissue chip array with gravity-driven flow for cancer research.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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5-axis CNC micro-milling machine for three-dimensional microfluidics

Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D4LC00496E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Mitchell Modarelli, Devin Kot-Thompson, Kazunori Hoshino
The gold standard of microfluidic fabrication techniques, SU-8 patterning, requires photolithography equipment and facilities and is not suitable for 3D microfluidics. A 3D printer is more convenient and may achieve...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Impact of microchannel width on axons for brain-on-chip applications

Lab Chip, 2024, 24,5155-5166
DOI: 10.1039/D4LC00440J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Katarina Vulić, Giulia Amos, Tobias Ruff, Revan Kasm, Stephan J. Ihle, Joël Küchler, János Vörös, Sean Weaver
Axon growth is influenced by the width and number of microchannels, with growth cone adaptability reaching its limit for constraints smaller than 350 nm. Tradeoffs between axon growth and control need to be made for neurofluidic devices.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Optical tweezer-assisted cell pairing and fusion for somatic cell nuclear transfer within an open microchannel

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00561A, Paper
Yidi Zhang, Han Zhao, Zhenlin Chen, Zhen Liu, Hanjin Huang, Yun Qu, Yaowei Liu, Mingzhu Sun, Dong Sun, Xin Zhao
We developed a somatic cell nuclear transfer-electrofusion system for pairing and fusing oocytes and somatic cells with a thousand-fold volume difference. The system showed a 90.56% pairing efficiency, potentially boosting batch cloning efficiency.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Observing root growth and signalling responses to stress gradients and pathogens using the bi-directional dual-flow RootChip

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00659C, Paper
Open Access
Claudia Allan, Yiling Sun, Stephen C. Whisson, Michael Porter, Petra C. Boevink, Volker Nock, Claudia-Nicole Meisrimler
Using a bi-directional dual-flow RootChip with integrated force sensing micropillars, root growth and signalling responses to stress gradients and pathogens were studied in Arabidopsis thaliana, Nicotiana benthamiana and Solanum lycopersicum.
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SERS-based pump-free microfluidic chip sensor for highly sensitive competitive immunoassay of cortisol in human sweat

Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D4LC00858H, Paper
Siyue Xiong, Chushu Zhu, Chengxuan Wang, Peitao Dong, Xuezhong Wu
Cortisol, known as the "stress hormone," is secreted by the adrenal cortex. Measuring cortisol levels in body fluids is essential for evaluating stress levels, adrenal function, hormone imbalances, and psychological...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Two youngsters from Kochi determined to smash their disabilities on the badminton court

Atul Krishna and Jyothish Kumar defy physical limitations to excel in badminton, inspiring with their determination and talent.




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No child will be left out of school sports meet in future, says Sivankutty




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Police control room in Kochi gets bomb threat call




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Drenched in sweat, student volunteers have a bittersweet experience at sports meet in Kochi




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Kerala HC adjourns hearing on plea against land acquisition for Wayanad township




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Kerala High Court quashes criminal case against filmmaker Sreekumar Menon




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Civic authorities racing against time to save Central funds for Edakochi STP

The deadline for the ₹18.6-crore project is December 31, and failure to complete it in time will lead to the Corporation losing the Central share of ₹7.75 crore




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Union Minister Suresh Gopi inaugurates ‘Confluence-24’ in Kochi




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Laugh in life: Kochi-based comedians Abhishek and Akshay on their latest show, their inspirations and more

The duo has been performing stand-up comedy for around three years now.




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Media rights cannot be restricted: Kerala High Court

Expression by the media of any definitive opinion regarding the guilt or innocence of a party in an ongoing criminal investigation will not get protection under Article 19(1)(a), observes an HC bench




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A man’s love affair with a sport that gave him a life




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Tooth-brushing event held to create awareness about oral health among children




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A champion pole-vaulter aims to bow out on a high




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Softball teams raise the roof as they whip up excitement at Parade Ground




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HC declines former Chief Secretary’s plea seeking exemption from personal appearance

Court exempts Palakkad Collector from personal appearance on condition that she will appear through virtual mode




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HC flays police inaction in clearing blockade to Thiruvananthapuram Corporation office




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Thrissur and Kochi take early lead as curtain goes up on CBSE State Kalotsav




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Not afraid of any probe, says Mamkootathil




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Kerala, Tamil Nadu united to ensure that India belongs to everyone, says Kanimozhi

DMK MP Kanimozhi was addressing an event held at the Ernakulam Town Hall to felicitate Sr. Vinitha, director of St. Teresa’s College, for her contributions to higher education, social welfare, and culture.




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Coastal States must register all fishing vessels, says Union Minister George Kurian

George Kurian emphasises the need for a framed regulation and policy to improve the livelihood of the fishing community and increase the number of vessels to optimally exploit the country’s marine fisheries resources




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New CEO for Kochi Biennale Foundation




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Seaplanes have potential to woo high-budget tourists to Kerala: Biju Prabhakar

Aviation Secretary says these amphibious aircraft can link tourism locales in the State. A seaplane will operate a trial service from Kochi International Marina to the Mattupetty dam in Munnar on Monday




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Seaplane arrives in Kochi backwaters for demo flight to Mattupetty Dam

Seaplane service will boost tourism by fostering new enterprises and creating job opportunities allowing holidaymakers to explore more destinations quickly, say Tourism Secretary




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Seaplane demo flight in Kochi draws mixed response




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Delay in completing work on ferry jetties hits commuters in West Kochi

Irrigation department is reportedly being blamed for the delay in completing dredging at Mattancherry Jetty; delay in renovating the Customs Jetty is causing safety issues, CSML asks contractor to expedite work




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HC asks Wayanad DLSA to formulate action plan to prevent child marriages among tribal communities




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Illegally mined sand, vehicles seized in Ernakulam




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Hits below the belt

"John le Carré's conduct in your pages is like ... that of a man who, having relieved himself in his own hat, makes haste to clamp the brimming chapeau on his head."



  • R K Nair

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Cashing in on calamity

Fleecing the pilgrims is big business in this country.



  • R K Nair

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The politics of child marriage

India's stand at the UN Human Rights Council was viewed with apprehension by the intelligentsia in Kerala. Many see it as yet another example of appeasement politics.



  • R K Nair

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Grizzly should repeat in the Chief Minister’s Trophy




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Geographique and Regina Memorabilis show out




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Vyasa, Lockheed, Ravishing Form, Nyx and Eastern Gold please




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Chief Minister’s Trophy declared null and void due to false start




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Isnt She Beautiful for the Mysore Dasara Sprint Championship




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Tom Cruiser wins Mysore Dasara Sprint Championship-2024




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Pissarro for the Suresh Mahindra Trophy




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African Gold, Czar, Double Scotch, My Solitaire, Jersey King and Magnetic shine




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Magneto claims the Suresh Mahindra Trophy




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Nyx, Excellent Lass and Balmoral shine




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Bourbonaire and High Opinion shine