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Govt in talks with industry on production of Gilead's remdesivir for trials

By www.business-standard.com
Published On :: Fri, 08 May 2020 20:18:00 +0530

Checks with industry on when can production begin here for trials


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Additional manpower may be sought from Centre to give police rest: Uddhav

By www.business-standard.com
Published On :: Fri, 08 May 2020 21:36:00 +0530

Uddhav also admitted that while the spread of the virus has been contained, the state has not succeeded in breaking the chain of infection yet


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16 migrant workers run over by goods train while sleeping on tracks

By www.business-standard.com
Published On :: Fri, 08 May 2020 22:51:00 +0530

The Railways announced a comprehensive probe into the accident which occurred at 5.15 am near Karmad, around 30 km from Aurangabad city


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Long walk home ends in tragedy: Goods train mows down 16 migrants

By www.business-standard.com
Published On :: Sat, 09 May 2020 02:09:00 +0530

Migrants fell asleep on railway track in Maharashtra


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Covid-19 crisis: Won't deploy Army in Mumbai, says Uddhav Thackeray

By www.business-standard.com
Published On :: Sat, 09 May 2020 02:10:00 +0530

Thackeray said his government has requested for doctors from the Railways, port trust and other central departments for support


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Coronavirus LIVE: 3,320 cases, 95 deaths in 24 hrs, India tally at 59,695

By www.business-standard.com
Published On :: Sat, 09 May 2020 07:13:00 +0530

Coronavirus update: Stay tuned with Business Standard for latest news on coronavirus, world death toll, and cases across the world and in India


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Covid-19 Factoid: India's recovery rate improves to 30% from 10% in April

By www.business-standard.com
Published On :: Sat, 09 May 2020 07:30:00 +0530

But news from Russia and Belgium is worrisome - while the former has seen an unprecedented surge in new cases, the latter's death rate has been rising rapidly


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World coronavirus dispatch: How the wealth management industry is changing

By www.business-standard.com
Published On :: Sat, 09 May 2020 07:34:00 +0530

From US-China talks to end trade deadlock, to FDA nod for Moderna drug's Phase-II trials, and an Amsterdam restaurant with 'quarantine greenhouses' - read these and more in today's world dispatch


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Aarogya Setu most downloaded healthcare app in the world, says Amitabh Kant

By www.business-standard.com
Published On :: Sat, 09 May 2020 08:16:00 +0530

Aarogya Setu is currently available on iOS and Android, and nearly 9 crore users have already downloaded the app


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Coronavirus LIVE: Testing scaled up to 95,000 per day, says Harsh Vardhan

By www.business-standard.com
Published On :: Sat, 09 May 2020 10:39:00 +0530

Coronavirus India update: Stay tuned with Business Standard for latest news on COVID-19, world death toll, and cases across the world and in India


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Work on to neutralise remaining Styrene gas at LG Polymers' Vizag plant

By www.business-standard.com
Published On :: Sat, 09 May 2020 11:36:00 +0530

The Chief Secretary said the gas leak resulted in 12 deaths, while 454 others had to be admitted to various hospitals


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OCI card holders' entry in India to remain suspended during lockdown: Govt

By www.business-standard.com
Published On :: Sat, 09 May 2020 11:39:00 +0530

The government has kept in abeyance multiple-entry life-long visas given to OCI card holders till the time international travel resumes


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Talks with experts: No strategy, only want to show the glimpses, says Rahul

By www.business-standard.com
Published On :: Sat, 09 May 2020 11:54:00 +0530

According to Congress sources, in the series of Rahul Gandhi's talks with experts, the will be a conversation with German virologist and several personalities from other fields on Covid-19


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Aurangabad train accident: Raised an alarm but to no avail, says eyewitness

By www.business-standard.com
Published On :: Sat, 09 May 2020 12:40:00 +0530

As many as 16 migrant labourers were killed and five others injured when a freight train ran over them between Jalna and Aurangabad on Friday


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Vande Bharat Mission: Indians to arrive from Bangladesh, Gulf, UK today

By www.business-standard.com
Published On :: Sat, 09 May 2020 12:51:00 +0530

India had on Monday announced it would begin a phased repatriation of its citizens stranded abroad starting May 7


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I am healthy, not suffering from any disease: Amit Shah issues statement

By www.business-standard.com
Published On :: Sat, 09 May 2020 18:28:00 +0530

"I am totally healthy and I am not suffering from any disease," he said in the statement in Hindi which was posted on his Twitter handle


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Optically-controlled closable microvalves for polymeric centrifugal microfluidic devices

By feeds.rsc.org
Published On ::

Lab Chip, 2020, 20,1426-1440
DOI: 10.1039/C9LC01187K, Paper
M. Shane Woolf, Leah M. Dignan, Hannah M. Lewis, Christopher J. Tomley, Aeren Q. Nauman, James P. Landers
Microvalving is a pivotal component in many microfluidic lab-on-a-chip platforms and micro-total analysis systems (μTAS).
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A liquid biopsy-guided drug release system for cancer theranostics: integrating rapid circulating tumor cell detection and precision tumor therapy

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Published On ::

Lab Chip, 2020, 20,1418-1425
DOI: 10.1039/D0LC00149J, Paper
Chun-Miao Xu, Man Tang, Jiao Feng, Hou-Fu Xia, Ling-Ling Wu, Dai-Wen Pang, Gang Chen, Zhi-Ling Zhang
A system integrating diagnostic and therapeutic functions for cancer is presented using magnetically controlled microfluidics.
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Colorimetric absorbance mapping and quantitation on paper-based analytical devices

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Published On ::

Lab Chip, 2020, 20,1441-1448
DOI: 10.1039/D0LC00028K, Paper
Open Access
Yoshiki Soda, Kye J. Robinson, Thomas J. Cherubini, Eric Bakker
A pixel-level colorimetric absorbance analysis can measure the total quantity of dye on paper, irrespective of shape and size.
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Multi-corneal barrier-on-a-chip to recapitulate eye blinking shear stress forces

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Published On ::

Lab Chip, 2020, 20,1410-1417
DOI: 10.1039/C9LC01256G, Paper
Rodi Abdalkader, Ken-ichiro Kamei
Human corneal epithelium coexists with tear fluids and shows its barrier functionality under the dynamic conditions of eye blinking. We developed a microfluidic platform enabling the dynamic culture of the human corneal barrier with recapitulation of eye blinking.
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Advanced 96-microtiter plate based bioelectrochemical platform reveals molecular short cut of electron flow in cytochrome P450 enzyme

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Published On ::

Lab Chip, 2020, 20,1449-1460
DOI: 10.1039/C9LC01220F, Paper
Ronny Frank, Christoph Prönnecke, Ronny Azendorf, Heinz-Georg Jahnke, Annette G. Beck-Sickinger, Andrea A. Robitzki
We developed a novel 96-well microtiter plate based bioelectrochemical platform with a vertical divided cell three-electrode architecture and a 96-multipotentiostat to perform fully parallelised bioelectrocatalytic screenings on redox enzymes.
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An implantable multifunctional neural microprobe for simultaneous multi-analyte sensing and chemical delivery

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Published On ::

Lab Chip, 2020, 20,1390-1397
DOI: 10.1039/D0LC00021C, Communication
Bo Wang, Ximiao Wen, Yan Cao, Shan Huang, Hoa A. Lam, Tingyi “Leo” Liu, Pei-Shan Chung, Harold G. Monbouquette, Pei-Yu Chiou, Nigel T. Maidment
PDMS thin-film transfer and enzyme microstamping enabled 3-in-1 Si/PDMS hybrid chemtrode for multi-analyte sensing and chemical delivery in vivo.
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Droplet encapsulation improves accuracy of immune cell cytokine capture assays

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Published On ::

Lab Chip, 2020, 20,1513-1520
DOI: 10.1039/C9LC01261C, Paper
Yuan Yuan, Julie Brouchon, J. Mauricio Calvo-Calle, Jing Xia, Li Sun, Xu Zhang, Kiera L. Clayton, Fangfu Ye, David A. Weitz, John A. Heyman
In-droplet cytokine capture assays combined with FACS to accurately identify and isolate activated immune cells.
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Monitoring tissue-level remodelling during inflammatory arthritis using a three-dimensional synovium-on-a-chip with non-invasive light scattering biosensing

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Published On ::

Lab Chip, 2020, 20,1461-1471
DOI: 10.1039/C9LC01097A, Paper
Open Access
Mario Rothbauer, Gregor Höll, Christoph Eilenberger, Sebastian R. A. Kratz, Bilal Farooq, Patrick Schuller, Isabel Olmos Calvo, Ruth A. Byrne, Brigitte Meyer, Birgit Niederreiter, Seta Küpcü, Florian Sevelda, Johannes Holinka, Oliver Hayden, Sandro F. Tedde, Hans P. Kiener, Peter Ertl
We demonstrate that the integration of complex human synovial organ cultures in a lab-on-a-chip provides reproducible and reliable information on how systemic stress factors affect synovial tissue architectures using light scatter biosensing.
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Scalable microfluidic droplet on-demand generator for non-steady operation of droplet-based assays

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Published On ::

Lab Chip, 2020, 20,1398-1409
DOI: 10.1039/C9LC01103J, Paper
Open Access
Kartik Totlani, Jan-Willem Hurkmans, Walter M. van Gulik, Michiel T. Kreutzer, Volkert van Steijn
We developed a microfluidic droplet on-demand (DoD) generator that enables the production of droplets with a volume solely governed by the geometry of the generator for a range of operating conditions.
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Rapid lipolytic oscillations in ex vivo adipose tissue explants revealed through microfluidic droplet sampling at high temporal resolution

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Published On ::

Lab Chip, 2020, 20,1503-1512
DOI: 10.1039/D0LC00103A, Paper
Juan Hu, Xiangpeng Li, Robert L. Judd, Christopher J. Easley
High temporal resolution sampling and quantitative detection of glycerol secretion dynamics from adipose tissue using our automated, droplet-based microfluidic system.
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Contact lens-based lysozyme detection in tear using a mobile sensor

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Published On ::

Lab Chip, 2020, 20,1493-1502
DOI: 10.1039/C9LC01039D, Paper
Zachary Ballard, Sarah Bazargan, Diane Jung, Shyama Sathianathan, Ashley Clemens, Daniel Shir, Saba Al-Hashimi, Aydogan Ozcan
A rapid and cost-effective method for monitoring proteins in tear-fluid is reported, which enables biomarker monitoring using contact lenses toward personalized mobile-health applications.
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Applications of the microphysiology systems database for experimental ADME-Tox and disease models

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Published On ::

Lab Chip, 2020, 20,1472-1492
DOI: 10.1039/C9LC01047E, Paper
Open Access
Mark Schurdak, Lawrence Vernetti, Luke Bergenthal, Quinn K. Wolter, Tong Ying Shun, Sandra Karcher, D. Lansing Taylor, Albert Gough
The Microphysiology Systems Database (MPS) is a critical tool for the design, management, analysis, and sharing of MPS study data.
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Mathematical modeling and computational analysis of centrifugal microfluidic platforms: a review

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Published On ::

Lab Chip, 2020, 20,1318-1357
DOI: 10.1039/C9LC00775J, Critical Review
Open Access
Masoud Madadelahi, Luis F. Acosta-Soto, Samira Hosseini, Sergio O. Martinez-Chapa, Marc J. Madou
This paper focuses on theory and computational modelling of lab-on-a-disc devices of relevance for novel applications discovery and optimal designs.
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Nanoplasmon-enhanced drop-screen for high throughput single-cell nucleocytoplasmic miRNA profiling

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01226E, Paper
Jia Liu, Guoyun Sun, Shih-Chung Wei, Song Guo, Weikang Nicholas Lin, Chia-Hung Chen
Nanoplasmon-enhanced drop screen is developed to measure single-cell multiple miRNAs with high sensitivity of 0.1 nM, addressing cell nucleocytoplasmic profile in a throughput ∼100 cells per minute.
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Stretching DNA to twice the normal length with single-molecule hydrodynamic trapping

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01028A, Paper
Open Access
Yan Jiang, Theodore Feldman, Julia A. M. Bakx, Darren Yang, Wesley P. Wong
High-speed hydrodynamic trapping enables combined surface-free force spectroscopy and fluorescence imaging of single DNA molecules at extreme forces.
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Development of two-photon polymerised scaffolds for optical interrogation and neurite guidance of human iPSC-derived cortical neuronal networks

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01209E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
J. A. Crowe, A. El-Tamer, D. Nagel, A. V. Koroleva, J. Madrid-Wolff, O. E. Olarte, S. Sokolovsky, E. Estevez-Priego, A.-A. Ludl, J. Soriano, P. Loza-Alvarez, B. N. Chichkov, E. J. Hill, H. R. Parri, E. U. Rafailov
We identified photopolymers for 2-photon polymerisation with biocompatibility for human iPSC-derived neural network development. Generation of microscale scaffold topologies enabled neurite guidance, demonstrating use in reproducing aligned networks.
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Seeded droplet microfluidic system for small molecule crystallization

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00122H, Paper
N. Garg, R. Tona, P. Martin, P. M. Martin-Soladana, G. Ward, N. Douillet, D. Lai
A microfluidic approach to seeded crystallization has been demonstrated using abacavir hemisulfate, a nucleoside analog reverse transcriptase inhibitor, in droplet reactors to control polymorphism and produce particles with a low particle size distribution.
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SLOCK (sensor for circadian clock): passive sweat-based chronobiology tracker

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00134A, Paper
Sayali Upasham, Shalini Prasad
SLOCK is a sweat based platform for monitoring circadian relevant biomarkers-cortisol and DHEA, using electrochemical detection modality.
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Microfluidic device for high-throughput affinity-based isolation of extracellular vesicles

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01190K, Paper
Ting-Wen Lo, Ziwen Zhu, Emma Purcell, Daniel Watza, Joyful Wang, Yoon-Tae Kang, Shruti Jolly, Deepak Nagrath, Sunitha Nagrath
Immunoaffinity based EV isolation technologies use antibodies targeting surface markers on EVs to provide higher isolation specificity and purity compared to existing approaches.
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Direct loading of blood for plasma separation and diagnostic assays on a digital microfluidic device

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00302F, Paper
Christopher Dixon, Julian Lamanna, Aaron R. Wheeler
The integration of 3D porous membranes in a digital microfluidic device enables the generation of cell-free plasma from finger-stick volumes of blood with in-line, on-chip analysis.
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In situ generation of plasma-activated aerosols via surface acoustic wave nebulization for portable spray-based surface bacterial inactivation

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00001A, Paper
Kiing S. Wong, William T. H. Lim, Chien W. Ooi, Leslie Y. Yeo, Ming K. Tan
We demonstrate an efficient technique for in situ production and application of plasma-activated aerosols for surface disinfection.
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Correction: Deformability-induced lift force in spiral microchannels for cell separation

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC90036B, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ewa Guzniczak, Oliver Otto, Graeme Whyte, Nicholas Willoughby, Melanie Jimenez, Helen Bridle
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A new polymer lab-on-a-chip (LOC) based on a microfluidic capillary flow assay (MCFA) for detecting unbound cortisol in saliva

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00071J, Paper
Vinitha T. U., Sthitodhi Ghosh, Alexander Milleman, Thinh Nguyen, Chong H. Ahn
A new polymer lab-on-a-chip with on-chip dried reagents for microfluidic capillary flow assay (MCFA) detection of unbound cortisol in saliva.
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Photonic crystal-based smart contact lens for continuous intraocular pressure monitoring

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01268K, Paper
Bohee Maeng, Hyung-kwan Chang, Jungyul Park
A powerless smart contact lens enabling to monitor intraocular pressure (IOP) by checking the visual color change in photonic crystal structure with a microhydraulic amplification system has been realized.
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Spatially isolated reactions in a complex array: using magnetic beads to purify and quantify nucleic acids with digital and quantitative real-time PCR in thousands of parallel microwells

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00069H, Paper
W. Hampton Henley, Nathan A. Siegfried, J. Michael Ramsey
Encoded beads carrying primer pairs for nucleic acid targets are used for sample preparation and multiplexed-in-space digital PCR quantification.
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Multiplexed homogeneous digital immunoassay based on single-particle motion analysis

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00079E, Paper
Kenji Akama, Hiroyuki Noji
Homogeneous digital immunoassay is a powerful analytical method for highly sensitive biomarker detection with a simple protocol. By using this method, we demonstrated the simultaneous multiple protein detection.
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Nanocrystal synthesis, μfluidic sample dilution and direct extraction of single emission linewidths in continuous flow

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00213E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ioannis Lignos, Hendrik Utzat, Moungi G. Bawendi, Klavs F. Jensen
We present a flow-based system coupled with an optical interferometry setup for the extraction of single nanocrystal properties.
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Acoustic separation of living and dead cells using high density medium

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00175A, Paper
Open Access
Karl Olofsson, Björn Hammarström, Martin Wiklund
A novel, simple and robust route for binary separation of viable and dead cells using a density modified medium which takes advantage of the compromised cell membrane of dead cells.
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Bioinspired reconfiguration of 3D printed microfluidic hydrogels via automated manipulation of magnetic inks

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00280A, Communication
Amin Mansoorifar, Anthony Tahayeri, Luiz E. Bertassoni
We proposed a novel concept for reconfiguration of hydrogel microfluidic devices, where multiple fluidic pathways could be generated via reversible manipulation of magnetic inks.
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Capacitive Sensing of Triglyceride Film Reactions: A Proof-of-Concept Demonstration for Sensing in Simulated Duodenal Contents with Gastrointestinal Targeting Capsule System

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Published On ::

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00133C, Paper
George Banis, Luke Beardslee, Justin Stine, Rajendra Mayavan Sathyam, Reza Ghodssi
Ingestible capsule systems continue evolving to overcome drawbacks associated with traditional gastrointestinal (GI) diagnostic and therapeutic processes, such as location restrictions or insufficient sensitivity measures when obtaining information on local...
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Catalytic exchange of hydrogen isotopes intensified by two-phase stratified flow in wettability designable microchannels

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Published On ::

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00250J, Paper
Yuexiao Song, Feng Xin, Yongsheng Xu
This work develops a reliable method to achieve stratified flow in squared cross-section microchannels by endowing the four channel walls with very different wettabilities. The gas–liquid flows are studied experimentally...
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PRESCIENT: platform for the rapid evaluation of antibody success using integrated microfluidics enabled technology

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Published On ::

Lab Chip, 2020, 20,1628-1638
DOI: 10.1039/C9LC01165J, Paper
Jose A. Wippold, Han Wang, Joseph Tingling, Julian L. Leibowitz, Paul de Figueiredo, Arum Han
Identifying antibodies (Abs) that neutralize infectious agents is the first step for developing therapeutics, vaccines, and diagnostic tools for these infectious agents.
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Auto-affitech: an automated ligand binding affinity evaluation platform using digital microfluidics with a bidirectional magnetic separation method

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Published On ::

Lab Chip, 2020, 20,1577-1585
DOI: 10.1039/D0LC00024H, Paper
Jingjing Guo, Li Lin, Kaifeng Zhao, Yanling Song, Mengjiao Huang, Zhi Zhu, Leiji Zhou, Chaoyong Yang
An automated ligand binding affinity evaluation platform using digital microfluidics with a bidirectional magnetic separation method that reduces the bead loss.
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Microfluidic device to study flow-free chemotaxis of swimming cells

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Published On ::

Lab Chip, 2020, 20,1639-1647
DOI: 10.1039/D0LC00045K, Paper
Nicolas Garcia-Seyda, Laurene Aoun, Victoria Tishkova, Valentine Seveau, Martine Biarnes-Pelicot, Marc Bajénoff, Marie-Pierre Valignat, Olivier Theodoly
Permeable agarose barriers allow flow-free gradient generation, applicable to adherent and non-adherent (swimming) cells, as well as co-culture experiments.
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