b

EU, Belgium, Denmark and Germany envoys visit Adani's Khavda, Mundra businesses, Gautam Adani says It was a privilege




b

Vegetable prices sky-rocket in October, food inflation at 10.87%, CPI at 6.21 %




b

India's index of industrial production shows 3.1 per cent growth in September 2024




b

Public Sector Banks records strong performance in 1st half of FY25




b

India will continue to be vocal about climate finances at COP29




b

Integrated manufacturing cluster to be developed in Bihar's Gaya




b

Centre to deliberate on plans to achieve 500 GW green energy target by 2030




b

India's infrastructure push to be among largest in 21st century: KPMG




b

India set to become 'major producer' of electric vehicles like China: Mark Mobius




b

Coal import for blending purposes in power generation declines by 8.5% during April-Sept 2024




b

India could save 91,000 crore rupees on import bill through biofuel blending: Hardeep Singh Puri




b

An Efficient All-Visible Light-Activated Photoswitches Based on Diarylethenes and CdS Quantum Dots

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06110A, Edge Article
Open Access
Kezhou Chen, Jiayi Liu, Joakim Andréasson, Bo Albinsson, Tiegen Liu, Lili Hou
All-visible light-activated diarylethene (DAE) photoswitches are highly attractive for applications in smart photoresponsive materials. Photocyclization of DAE via the low-lying excited triplet state through triplet energy transfer (TET) from a...
The content of this RSS Feed (c) The Royal Society of Chemistry




b

Phase transition induced hydrogen activation for enhanced furfural reductive amination over CoCu bimetallic catalyst

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05885B, Edge Article
Open Access
Yilin Wei, Zixu Ma, Beibei Liu, Jialin Yang, Dan Wu, Yongsheng Zhang, Yuexing Zhang, Charles Chunbao Xu, Renfeng Nie
The synthesis of primary amines from renewable biomass and its derivatives through reductive amination has garnered significant attention. How to construct efficient non-noble-metal catalysts that enable low-temperature catalysis still remains...
The content of this RSS Feed (c) The Royal Society of Chemistry




b

TcESTIME: predicting high-temperature hydrogen-based superconductors

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC04465G, Edge Article
Open Access
Trinidad Novoa, Matías E. di Mauro, Diego Inostroza, Kaoutar El Haloui, Nicolas Sisourat, Yvon Maday, Julia Contreras-García
Superconductivity can be considered among the most exciting discoveries in material science of the XXth century. However, the hard conditions for the synthesis and the difficult characterization, make the statement...
The content of this RSS Feed (c) The Royal Society of Chemistry




b

Gaining the Molecular Design Principles for Efficient Diarylethene Photoacid and Photohydride Generators Based on Photochemical Reaction Mechanism

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06202G, Edge Article
Open Access
Yifan Su, Dexin Zheng, Lingfeng Ge, Le Yu, David Lee Phillips, Jiani Ma, Yu Fang
Abstract: Photoacid generators (PAGs) and photohydride generators (PHGs) are specific photolabile protecting groups that release acid and hydride, respectively. Over the past decade, great efforts have been devoted to developing...
The content of this RSS Feed (c) The Royal Society of Chemistry




b

Synthesis of highly condensed phospholes by Lewis acid-assisted dehydrogenative Mallory reaction under visible light irradiation

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05657D, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ikki Kamiyoshi, Yuki Kojima, Shibo Xu, Kosuke Yasui, Yuji Nishii, Koji Hirano
A photo-promoted oxidative cyclization, that is, Mallory reaction of 2,3-diarylbenzophopholes has been developed. With an assistance of Bi(OTf)3 Lewis acid, the reaction proceeds smoothly under visible light irradiation even without...
The content of this RSS Feed (c) The Royal Society of Chemistry




b

'PM Modi's govt gives highest priority to over 35 mn Indian diaspora', says EAM Jaishankar on website launch for Pravasi Bharatiya Divas




b

$19 mn Loss & Damage funding pledged by Sweden at COP29, bringing total pledged funding to $720 mn




b

Providing better healthcare biggest priority: PM Modi ahead of Darbhanga AIIMS inauguration




b

Chandigarh's air quality continues to be worse than Punjab, Haryana




b

India's CO2 emissions account 8pc of global total, to rise by 4.6pc in 2024: Report




b

Assam: Army celebrates 'National Education Day' with students in Tinsukia




b

UP: Devotees celebrate 'Tulsi Vivah' at Balua Ghat in Prayagraj, marking sacred union of Lord Vishnu, Vrinda




b

BRO rescues 20 vehicles stuck in snow in J-K's Bandipora




b

Defence Space Agency hosts first ever space exercise 'Antariksha Abhyas - 2024' in Delhi




b

There will be census in country but not based on caste: Union Minister Shobha Karandlaje




b

Rajnath Singh stresses on adaptive defence to cope with Age of Grey Zone, hybrid warfare




b

Union Jal Shakti Minister CR Paatil chairs 13th high-powered review meeting of Brahmaputra Board




b

AI and hi-tech technologies will be used in CCTV arrangements: UP DGP Prashant Kumar on Mahakumbh 2025 preparations




b

Assam Governor attends Sainik school Goalpara's Diamond Jubilee celebrations




b

All cases related to loan fraud at Perumbavoor Urban Cooperative Society to be handed over to Crime Branch

Police say 29 cases have been registered. Probe by district joint registrar of Cooperative department finds 26 persons, mostly members of previous director boards, accountable for irregularities to the tune of ₹33.33 crore




b

No gaps in management of biodegradable waste, Kerala tells NGT




b

French lower house rejects massively amended 2025 budget

Prime Minister Michel Barnier's minority government now has a largely free hand in submitting a cleaned-up text to the Senate upper house




b

Afghanistan attends U.N. climate talks for first time since Taliban return to power

Afghanistan’s first delegation at United Nations climate talks since the Taliban’s return to power in 2021 has arrived in Baku, Azerbaijan




b

Uzbekistan to make media, songs and films pass 'moral test'

President Shavkat Mirziyoyev has introduced some reforms since coming to power after the 2016 death of dictator Islam Karimov, but rights groups say the country remains deeply authoritarian




b

Fifth storm in a month bears down on the Philippines

The local government also reported knee-high floods across Santiago, a city of 1,50,000 people along an upper bank of the Cagayan river




b

‘Anti-war’ comedy play riles Bulgarian nationalists

Last week’s premiere of Arms and the Man by renowned Irish-born playwright George Bernard Shaw sparked raucous protests by nationalist groups




b

Cold War-era H-6 bomber enhances China’s ability to strike U.S. bases

The H-6 long-range bomber was used in China’s October war games around Taiwan; it flew close to the U.S. mainland for first time in June




b

Iran executes in public a serial rapist convicted in dozens of cases

Iran’s state media say authorities have executed in public a man convicted of raping dozens of women over two decades




b

Lebanon media claims Israeli strike hit apartment south of Beirut

Israeli warplanes launched a strike at dawn targeting a residential apartment in a building in the Dawhet




b

France’s bullfighters see red over bill to ban under-16s

Although public opinion favours outlawing bullfighting in France, a bid to ban the practice failed in 2022




b

IndiGo, Air India cancel flights to Bali following volcanic eruption

The Mount Lewotobi Laki Laki volcano located in a remote island in East Nusa Tenggara province erupted earlier this month and has resulted in ash clouds




b

Sri Lanka to hold key parliamentary vote on November 14

President Anura Kumara Dissanayake’s ruling alliance is looking to secure a majority in Parliament




b

Senior Russian naval officer killed in car bombing claimed by Kyiv

Russia's state Investigative Committee said in a statement that an improvised explosive device had detonated in an act of terrorism, killing a serviceman whom it did not identify




b

In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP

RSC Med. Chem., 2024, 15,3674-3694
DOI: 10.1039/D4MD00580E, Research Article
Jinhua Ning, Nini Zhan, Zhanpan Wu, Yuzhe Li, Die Zhang, Yadian Shi, Yingxun Zhou, Chuan-Huizi Chen, Wenbin Jin
Oridonin analogue 11a showed significant antitumor efficacy in vitro via cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP accumulation, meanwhile, displayed much more stable than oridonin in human plasma.
The content of this RSS Feed (c) The Royal Society of Chemistry




b

New ATP-competitive inhibitors of E. coli GyrB obtained from the mapping of the hydrophobic floor at the binding site: synthesis and biological evaluation

RSC Med. Chem., 2024, 15,3759-3777
DOI: 10.1039/D4MD00498A, Research Article
Lucas Gutierrez, Peter Peršolja, Rodrigo Tosso, Nace Zidar, Danijel Kikelj, Ricardo D. Enriz
A diagram of the active site of E. coli gyrase B, highlighting the hydrophobic subsite, including key residues relevant to ligand binding.
The content of this RSS Feed (c) The Royal Society of Chemistry




b

Furoxan–piplartine hybrids as effective NO donors and ROS inducers in PC3 cancer cells: design, synthesis, and biological evaluation

RSC Med. Chem., 2024, 15,3778-3794
DOI: 10.1039/D4MD00281D, Research Article
Carolyne Brustolin Braga, Julio Cesar Milan, Matheus Andrade Meirelles, Bruno Zavan, Guilherme Álvaro Ferreira-Silva, Ester Siqueira Caixeta, Marisa Ionta, Ronaldo A. Pilli
A novel hybrid integrating piplartine with a furoxan moiety exhibited a sub-micromolar IC50 and extraordinary selectivity for PC3 cells, which was associated with its capacity to release NO, generate ROS, induce DNA damage, and trigger apoptosis.
The content of this RSS Feed (c) The Royal Society of Chemistry




b

Preventing SARS-CoV-2 infection using Fv-antibodies targeting the proprotein convertase (PPC) cleavage site

RSC Med. Chem., 2024, 15,3704-3710
DOI: 10.1039/D4MD00552J, Research Article
Jaeyong Jung, Jeong Soo Sung, Soonil Kwon, Hyung Eun Bae, Min-Jung Kang, Joachim Jose, Misu Lee, Jae-Chul Pyun
Fv-antibodies targeting the PPC region of SARS-CoV-2 to prevent infection, screened from an Fv-antibody library (displayed on outer membrane of E. coli cell).
The content of this RSS Feed (c) The Royal Society of Chemistry




b

Discovery of hybrid Glypromate conjugates with neuroprotective activity against paraquat-induced toxicity

RSC Med. Chem., 2024, 15,3711-3727
DOI: 10.1039/D4MD00584H, Research Article
Sara C. Silva-Reis, Vera M. Costa, Daniela Correia da Silva, David M. Pereira, Xavier Cruz Correia, Xerardo García-Mera, José E. Rodríguez-Borges, Ivo E. Sampaio-Dias
A series of bicyclic-based Glypromate conjugates with reduction of protein aggregation elicited by Aβ25–35 and neuroprotective activity against paraquat-induced toxicity is reported, paving the way for the discovery of novel neurotherapeutics.
The content of this RSS Feed (c) The Royal Society of Chemistry




b

Stachydrine, a pyrrole alkaloid with promising therapeutic potential against metabolic syndrome and associated organ dysfunction

RSC Med. Chem., 2024, 15,3652-3673
DOI: 10.1039/D4MD00425F, Review Article
Semim Akhtar Ahmed, Prasenjit Manna, Jagat Chandra Borah
Metabolic syndrome is a multifaceted condition marked by interconnected risk factors, significantly increasing the risk of serious diseases like cardiovascular disease, type 2 diabetes, and stroke.
The content of this RSS Feed (c) The Royal Society of Chemistry