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A bilayer hydrogel mimicking the periosteum-bone structure for innervated bone regeneration

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11187-11201
DOI: 10.1039/D4TB01923G, Paper
Wenhui Lyu, Yuyue Zhang, Shaopei Ding, Xiang Li, Tong Sun, Jun Luo, Jian Wang, Jianshu Li, Lei Li
The bilayer hydrogel GS@Mg/GP@Mg in this study is a promising material to promote innervated bone regeneration for functional and structural repair of bone defects.
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Improving the sulfite-detection performance of a fluorescent probe via post-synthetic modification with a metal–organic framework

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11251-11258
DOI: 10.1039/D4TB01754D, Paper
Jing-Yi Shi, Bin Wang, Xin-Yue Cui, Xiao-Wei Hu, Hai-Liang Zhu, Yu-Shun Yang
In this work, a post-synthetic modification strategy was attempted to improve the performance of the probe for sulfite detection.
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A dual-functional photosensitizer for mitochondria-targeting photodynamic therapy and synchronous polarity monitoring

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11259-11264
DOI: 10.1039/D4TB01872A, Paper
Liu Yang, Shenglong Gan, Jie Zhang, Yin Jiang, Qingxin Chen, Hongyan Sun
A dual-functional photosensitizer was developed, exhibiting potent phototoxicity and sensitivity to polarity changes.
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A simple hydrogen peroxide-activatable Bodipy for tumor imaging and type I/II photodynamic therapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11165-11171
DOI: 10.1039/D4TB01650E, Paper
Fangqing Ge, Yujie Sun, Yu Wang, Dan Yu, Zhijia Wang, Fabiao Yu, Bingran Yu, Hongbing Fu
A H2O2-activatable Bodipy with simultaneous type I and type II photosensitization was designed for tumor imaging and therapy.
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Nordihydroguaiaretic acid microparticles are effective in the treatment of osteoarthritis

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11172-11186
DOI: 10.1039/D4TB01342E, Paper
Kaamini M. Dhanabalan, Bhagyashree Padhan, Ameya A. Dravid, Smriti Agarwal, Nicholas M. Pancheri, Angela Lin, Nick J. Willet, Ashok Kumar Padmanabhan, Rachit Agarwal
Sustained delivery of NDGA via polymeric microparticles maintains therapeutic levels in joints, reduces cartilage damage, and alleviates post-traumatic osteoarthritis (PTOA) in mice through ROS modulation and autophagy induction.
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Chitosan-functionalized nanobubbles for precision oncology: advances in targeted cancer therapeutics

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11076-11088
DOI: 10.1039/D4TB01930J, Review Article
Vivek Pandey, Tejasvi Pandey
The convergence of nanotechnology and cancer therapeutics has opened new frontiers in the development of advanced drug delivery systems.
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Microfluidic synthesis and accurate immobilization of low-density QD-encoded magnetic microbeads for multiplex immunoassay

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11230-11236
DOI: 10.1039/D4TB01585A, Paper
Zhou Sha, Tianyi Ling, Wenqi Yang, Haosu Xie, Chunnan Wang, Shuqing Sun
Accurate immobilization of microbeads in the gap of nickel patterns.
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Breakthrough in cancer therapy: lutetium texaphyrin–celecoxib conjugate for immune and photodynamic treatment

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB02019G, Highlight
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Qihang Ding, Yue Wang, Pengfei Zhang, Ling Mei
Kim et al. present a small-molecule photosensitizer, LuCXB, which combines a COX-2 inhibitor (celecoxib) with a near-infrared lutetium texaphyrin photocatalyst and was loaded CD133-aptamer functionalized exosome for cancer stem cells targeting.
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A guanidiniocarbonyl-pyrrole functionalized cucurbit[7]uril derivative as a cytomembrane disruptor for synergistic antibacterial therapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11105-11109
DOI: 10.1039/D4TB01840K, Communication
Ruixue Han, Kehan Du, Shengke Li, Minzan Zuo, Ponmani Jeyakkumar, Hao Jiang, Leyong Wang, Xiao-Yu Hu
A guanidiniocarbonyl-pyrrole functionalized cucurbit[7]uril derivative as a cytomembrane disruptor has been successfully constructed for synergistic antibacterial therapy.
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Nanobiopolymers in cancer therapeutics: advancing targeted drug delivery through sustainable and controlled release mechanisms

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00599F, Review Article
Shikha Gulati, Nabeela Ansari, Yamini Moriya, Kumud Joshi, Disha Prasad, Gargi Sajwan, Shefali Shukla, Sanjay Kumar, Rajender S. Varma
Nanobiopolymers in cancer therapeutics offer sustainable and targeted drug delivery with controlled release, enhancing treatment efficacy while ensuring sustainability and biodegradability for improved patient care.
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Nanomaterial-mediated photothermal therapy modulates tumor-associated macrophages: applications in cancer therapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01928H, Review Article
Yan Li, Yuhao Si, Heng Yin
Nanomaterials for modulating tumor-associated macrophages in photothermal therapy.
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Controlled therapeutic cholesterol delivery to cells for the proliferation and differentiation of keratinocytes

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11110-11122
DOI: 10.1039/D4TB01015A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Krzysztof Berniak, Ahmadreza Moradi, Agata Lichawska-Cieslar, Weronika Szukala, Jolanta Jura, Urszula Stachewicz
The research concept involves investigating how cholesterol endocytosis impacts cells using electrospun fibers as a carrier. We studied keratinocyte proliferation and evaluated gene expression levels for markers of early and late differentiation.
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Navigating predictions at nanoscale: a comprehensive study of regression models in magnetic nanoparticle synthesis

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB02052A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lukas Glänzer, Lennart Göpfert, Thomas Schmitz-Rode, Ioana Slabu
The transformative power of support vector regression in optimizing magnetic nanoparticle synthesis intricate relationships between process parameters and particle size, enabling the production of particles with tailored properties.
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Nanomaterials and methods for cancer therapy: 2D materials, biomolecules, and molecular dynamics simulations

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01667J, Review Article
Welela M. Kedir, Lunna Li, Yaw Sing Tan, Natasa Bajalovic, Desmond K. Loke
Nanomaterials made from 2D semiconductors and biomolecules are reviewed. Cell-nanoparticle interactions are examined in recent simulations. These nanomaterials and MD simulations reveal novel mechanisms and enable cancer drug delivery and targeting.
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Biomaterials Enhancing Localized Cancer Therapy Activated Anti-Tumor Immunity: A Review

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01995D, Review Article
Jipeng Yao, Zhencun Cui, Feifei Zhang, Haidong Li, Longlong Tian
Localized cancer therapy such as radiotherapy, phototherapy, and chemotherapy are precise cancer treatment strategy, aiming to minimize systemic side effect. However, cancer metastasis remains the primary cause of cancer patients’...
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Unravelling the molecular mechanobiology by DNA-Based fluorogenic tension sensor

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01858C, Review Article
Kaushik Pal
Investigation of the biological system reveals many underlying principles that govern the regular life processes. Recently, the analysis of tiny mechanical forces associated with many biological processes revels their significance...
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Lactobionic acid modified cobalt coordination polymer-coated peroxymonosulfate nanoparticles generate sulfate/hydroxy dual-radicals for targeted cancer therapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01777C, Paper
Jiahui Li, Jiaxuan Li, Zelong Chen, Yichen Wan, Yi Wang, Zhichao Pei, Yuxin Pei
LCP NPs were prepared by forming a coordination polymer on peroxymonosulfate through the coordination between imidazole-2-carboxaldehyde and Co2+, then modified with lactobionic acid to improve the efficacy of sulfate/hydroxy dual-radical therapy.
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H2O2-activated mitochondria-targeting photosensitizer for fluorescence imaging-guided combination photodynamic and radiotherapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01653J, Paper
Qiufen Tian, Zifan Zhu, Yun Feng, Shirui Zhao, Hui Lin, Wen Zhang, Zhiai Xu
Radiotherapy is a primary modality in cancer treatment but accompanied by severe side effects to healthy tissues and radiation resistance to some extent. To overcome these limitations, we developed a...
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Nanoparticles based image-guided thermal therapy and temperature feedback

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01416B, Review Article
Carlos Jacinto, Wagner Ferreira Silva, Joel Garcia, Gelo P. Zaragosa, Carlo Nonato De Jesus Ilem, Tasso O. Sales, Harrison D. A. Santos, Blessed Isaac C. Conde, Helliomar Pereira Barbosa, Sonia Malik, Surender Kumar Sharma
Nanoparticles have emerged as versatile tools in the realm of thermal therapy, offering precise control and feedback mechanisms for targeted treatments. This review explores the intersection of nanotechnology and thermal...
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Surface-Enhanced Raman Scattering for HSP 70A mRNA Detection in the Live Cells Using Silica Nanoparticles and DNA-Modified Gold Nanoparticles

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01514B, Paper
Ju Eun Cho, Dong-Kwon Lim
Real-time monitoring of mRNA in living cells is crucial for understanding dynamic biological processes. Traditional methods such as northern blotting, PCR, and sequencing require cell lysis and do not allow...
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Development of a Xanthene-Based NIR Fluorescent Probe for Accurate and Sensitive Detection of γ-Glutamyl Transpeptidase in Cancer Diagnosis and Treatment

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01841A, Paper
Chia-Kai Lai, KUPPAN MAGESH, Sivan Velmathi, Shu-Pao Wu
γ-Glutamyl transpeptidase (GGT) regulates glutathione (GSH), essential for cell functions and linked to cancer. High GGT levels in tumors make it a valuable cancer biomarker. Current GGT detection methods often...
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Cuproptosis in cancer therapy: mechanisms, therapeutic application and future prospects

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01877J, Review Article
Jiawei Hu, Junfei Zhu, Tao Chen, Yudie Zhao, Qingwen Xu, Yan Wang
Cuproptosis is a regulated form of cell death induced by the accumulation of metal ions and is closely linked to aspects of cellular drug resistance, cellular metabolism, and signalling pathways.
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Advancing cancer therapy with a heptamethine carbocyanine dye-conjugated radionuclide drug

By pubs.rsc.org
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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01798F, Paper
Mingxing Huang, Weichen Wang, Yingwei Wang, Rang Wang, Lili Pan, Xin Li, Bo Li, Jingsong Zhang, Ruoxiang Wang, Yi Zhang, Rong Tian
Malignant tumors pose substantial treatment challenges due to their heterogeneity, metastatic potential, and therapeutic resistance, underscoring the urgent need for more effective treatment options.
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Bimetallic doped carbon dot nanozymes for enhanced sonodynamic and nanocatalytic therapy

By pubs.rsc.org
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J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01916D, Paper
Yandong Huang, Lanting Jia, Shiqi Zhang, Lan Yan, Lei Li
The conventional inorganic semiconductors are not suitable for acting as nanozymes or sonosensitizers for in vivo therapeutic nanomedicine owing to the lack of excellent biocompatibility. Biocompatible carbon dots (CDs) exhibit...
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Micah Parsons insists he wasn't throwing "Mike McCarthy under the bus" with postgame comments

By sports.yahoo.com
Published On :: Wed, 13 Nov 2024 02:29:34 GMT

Cowboys edge rusher Micah Parsons pushed back against the perception he was taking a shot at coach Mike McCarthy in his postgame comments Sunday.


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'I won't be shedding my clothes in Bigg Boss 10'

By www.rediff.com
Published On :: Mon, 28 Nov 2016 15:30:42 +0530

'Don't worry I will fulfill your dreams, Jason Shah promises, just before he enters Bigg Boss 10.


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The This is Us Contest: Win COOL Prizes!

By www.rediff.com
Published On :: Wed, 07 Dec 2016 11:12:05 +0530

All you have to do is answer a simple question!


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Bigg Boss 10: Predict the winner!

By www.rediff.com
Published On :: Sat, 28 Jan 2017 10:00:18 +0530

Will it be Lopa or Bani? Manu or Manveer?


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For the great love of British TV shows

By www.rediff.com
Published On :: Tue, 25 Apr 2017 16:15:42 +0530

Love Sherlock, Dr Who, and Downton Abbey? Vanita Kohli-Khandekar finds out how the UK became one the world's largest creators of television content.


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Taking Made-in-India TV shows to the world

By www.rediff.com
Published On :: Tue, 09 May 2017 16:04:00 +0530

Can you imagine a show made in India beating both The Voice and The X-Factor on ratings?Vanita Kohli-Khandekar profiles Greymatter, the Indian content firm that made it possible.


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PIX: The Kaun Banega Crorepati Season 9 shoot begins

By www.rediff.com
Published On :: Thu, 10 Aug 2017 17:11:17 +0530

A look at the first day's pictures.


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