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Krishna district police launch Sakthi Teams to protect women, children

Keys handed over for two-wheelers to all-women members of the Sakthi teams




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Weak dependence [electronic resource] : with examples and applications / by Jérôme Dedecker, Paul Doukhan, Gabriel Lang, León R. José Rafael, Sana Louhichi, Clémentine Prieur

New York, NY : Springer New York, 2007




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Your death would be mine [electronic resource] : Paul and Marie Pireaud in the Great War / Martha Hanna.

Cambridge, Mass. : Harvard University Press , 2006.




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Folklife and superstition [electronic resource] : the luck, lore, and worldviews of prairie homesteaders / Sandra Rollings-Magnusson.

Surrey, BC : Heritage House Publishing, 2024.




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A novel in situ method for linear alkylbenzene sulfonate quantification in environmental samples using a digital image-based method

Anal. Methods, 2024, 16,2009-2018
DOI: 10.1039/D4AY00073K, Paper
Helayne S. de Sousa, Roxanny Arruda-Santos, Eliete Zanardi-Lamardo, Willian T. Suarez, Josiane L. de Oliveira, Renata A. Farias, Vagner Bezerra dos Santos
Surfactants spilled in water resulting in the contamination of aquatic environments being in situ monitored using a smartphone.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Sodium alginate hydrogelation mediated paper-based POCT sensor for visual distance reading and smartphone-assisted colorimetric dual-signal determination of L-lactate

Anal. Methods, 2024, 16,2077-2084
DOI: 10.1039/D4AY00041B, Paper
Wenjuan Wang, Danrong Chen, Yujiao Cai, Zijing Liu, Hongfen Yang, Hongbin Xie, Jinquan Liu, Shengyuan Yang
Here, we show a paper-based POCT sensor based on lactate dehydrogenase-mediated alginate gelation combined with visual distance reading and smartphone-assisted colorimetric dual-signal analysis to determine the concentration of L-lactate in yogurt samples.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Surface charge-induced electrospray for high-throughput analysis of complex samples and electrochemical reaction intermediates using mass spectrometry

Anal. Methods, 2024, 16,2002-2008
DOI: 10.1039/D4AY00276H, Communication
Yajie Huang, Yajun Zheng, Qianqian Zuo, Zhiming Zhang, Lixuan Zhu, Yun Li, Zhiping Zhang
A novel surface charge induced electrospray ionization is proposed due to its features of no contact between sample solution and metal electrode, fast analytical process (less than 40 s), and high analytical sensitivity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rapid and green quantification of phloridzin and trilobatin in Lithocarpus litseifolius (Hance) Chun (sweet tea) using an online pressurized liquid extraction high-performance liquid chromatography at equal absorption wavelength method

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00170B, Paper
Zhengming Qian, Qinggui Lei, Dan Tang, Guoying Tan, Qi Huang, Fucai Zhou, Wenhao Wang
Sweet tea is a functional herbal tea with anti-inflammatory, anti-diabetic, and other effects, in which phloridzin and trilobatin are two functional compounds.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Establishing a new methodology for determining the water absorbability of cellulose-derived materials via a vapor-monitoring headspace strategy

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02209A, Communication
Yi-Xian Gong, Wei-Qi Xie
In this research, for the first time, we introduce a vapor-monitoring headspace strategy to establish a new methodology for determining the water absorbability of cellulose-derived materials.
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Study on the affinity sites of cadmium's binding to ligands by thermodynamics and nuclear magnetic resonance spectroscopy

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02253F, Paper
Jinsong Yu, Xu Huang, Xiuxiu Wu, Hui Cao, Min Yuan, Tai Ye, Fei Xu
According to the experimental parameters for the interaction of Cd(II) with ligands, the binding sites of Cys and GSH were –SH, –NH2 and –COOH, and the thermodynamic behaviour of Cd(II) with Cys/GSH in boric acid and HEPES buffers was different, exothermic in HEPES but endothermic in boric acid.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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The selective extraction of dietary polyamines from chicken breast using the application of a lab-on-a-chip electromembrane and dispersive liquid–liquid microextraction followed by gas chromatography-mass spectrometry

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02172F, Paper
Fatemeh Barzegar, Samaneh Nabizadeh, Marzieh Kamankesh, Jahan B. Ghasemi, Abdorreza Mohammadi
Excessive dietary polyamines (PAs), including putrescine (PUT), spermine (SPM), and spermidine (SPD), have become a worldwide concern due to their carcinogenicity and reduced shelf life.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Simple and convenient preconcentration procedure for the isotopic analysis of uranium in seawater

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY01381B, Paper
Minami Abe, Noriaki Seko, Hiroyuki Hoshina, Shigeki Wada, Shinya Yamasaki, Keisuke Sueki, Aya Sakaguchi
Amidoxime adsorbent was synthesised by graft polymerisation. The adsorbent was efficient for collection of U in seawater for both the adsorption and desorption steps, thus affording a new strategy for measurement of U isotopes.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Near-infrared responsive gold nanorods for highly sensitive colorimetric and photothermal lateral flow immuno-detection of SARS-CoV-2

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00347K, Paper
Xiaohui Liu, Jingwen Li, Kun Wang, Xiang Li, Shenming Wang, Gengchen Guo, Qiaowen Zheng, Maosheng Zhang, Jingbin Zeng
We developed a colorimetric and photothermal dual-mode LFIA platform for sensitive and selective SARS-CoV-2 N protein detection based on gold nanorods.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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A simple, fast and inexpensive approach to quantify low concentrations of iron in biodiesel by voltammetry after extraction induced by microemulsion breaking

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00342J, Paper
Cristian Henrique Krause, Alexandre Batista Schneider, Leandro Kolling, Lauren Thauani Teixeira Oliveira, Márcia M. Silva
An alternative approach to assay iron (Fe) in biodiesel by differential pulse adsorptive cathodic stripping voltammetry (DPAdCSV) is presented herein. The sample treatment involved a simple, rapid, but effective extraction...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Caffeine quantification in dietary supplements using high-throughput on-line solid phase extraction coupled to Venturi easy ambient sonic-spray ionization mass spectrometry

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00333K, Paper
David Ulisses Tega, Luan Felipe Campos Oliveira, Patrick Cesar Ferreira, Bruna Beatriz Soldera, Heliara Dalva Lopes Nascimento, Marcos Nogueira Eberlin, Alessandra Sussulini
Optimization of a LC-V-EASI-MS system. Employment of LC-V-EASI-MS and online SPE to enhance analytical performance for caffeine determination reaching 90 s per sample.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Rapid detection of monkeypox virus and differentiation of West African and Congo Basin strains using endonuclease restriction-mediated real-time PCR-based testing

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00492B, Paper
Juan Zhou, Fei Xiao, Xiaolan Huang, Jin Fu, Nan Jia, Chunrong Sun, Min Chen, Zheng Xu, Hui Huang, Yi Wang
A novel multiplex ET-PCR assay that integrates PCR amplification, restriction endonuclease cleavage and real-time fluorescence detection was devised to diagnose MPXV infection and distinguish the Congo Basin and West Africa MPXV strains.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Ag-coated tetrapod gold nanostars (Au@AgNSs) for acetamiprid determination in tea using SERS combined with microfluidics

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00297K, Paper
Qian Ke, Limei Yin, Heera Jayan, Hesham R. El-Seedi, Xiaobo Zou, Zhiming Guo
The combination of highly sensitive SERS substrate core–shell Au@AgNSs and microfluidic chip featuring four circular split hybrid structures were used for quantitative detection of acetamiprid in tea. The LOD of acetamiprid was 0.048 ng mL−1.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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A novel fluorescent probe with a large Stokes shift for colorimetric and selective detection of cysteine in water, milk, cucumber, pear and tomato

Anal. Methods, 2024, 16,2322-2329
DOI: 10.1039/D3AY02322B, Paper
Lin Luo, Ranran Guo, Lianjie Wang, Xixi Song, Zhao Wang, Junliang Wu
A novel fluorescent probe for colorimetric and selective detection of cysteine was efficiently constructed through a simple and mild reaction conditions. Probe 2 displays a linear response to Cys concentrations (0–30 μM), low detection limit (0.89 μM), large Stoke shift (125 nm).
The content of this RSS Feed (c) The Royal Society of Chemistry




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Direct solid sample analysis of low-cost jewelry using spectroanalytical techniques: exploratory chemical data evaluation and metal migration with synthetic sweat

Anal. Methods, 2024, 16,2286-2291
DOI: 10.1039/D4AY00325J, Paper
Thaila Lorena de Araújo, Fabiola Manhas Verbi Pereira, Edenir Rodrigues Pereira-Filho
Jewelry samples were directly analyzed using LIBS and XRF.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A highly sensitive and selective fluorescent biosensor for breast cancer derived exosomes using click reaction of azide–CD63 aptamer and alkyne-polymer dots

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00146J, Paper
Dumei Ma, Yiting Luo, Xiaoya Zhang, Zehu Xie, Yinghua Yan, Chuan-Fan Ding
A fluorescence method based on Cu-triggered click reaction of azide modified CD63 aptamer and alkyne capped Pdots was developed for breast cancer derived exosome detection.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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A reaction based carbazole–indolium conjugate probe for the selective detection of environmentally toxic ions

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00301B, Paper
Jayasudha Palanisamy, Mansour K. Gatasheh, Ashraf Atef Hatamleh
Carbazole–indolium based colorimetric probe was designed for detecting cyanide ions in various water samples. An outstanding response was shown by paper test strips prepared using the probe for the easy detection of cyanide in real time.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Novel advanced materials and magnetic solid phase extraction as approaches in sample preparation to enhance the analysis of ochratoxin A in peanuts

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00246F, Paper
Bingchen Wang, Yifan Wang, Xiuyuan Zhang, Kuo He
In order to improve the detection efficiency of ochratoxin, a superparamagnetic nano-material was synthesized for solid phase extraction of ochratoxin.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A colorimetric tandem combination of CRISPR/Cas12a with dual functional hybridization chain reaction for ultra-sensitive detection of mycobacterium bovis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D3AY02200E, Paper
Qiong Liu, Mei Yang, He Zhang, Wenjie Ma, Xin Fu, Huiqing Li, Sainan Gao
Tuberculosis caused by Mycobacterium bovis poses a global infectious threat to humans and animals. Therefore, there is an urgent need to develop a sensitive, precise, and easy-to-readout strategy. Here, a...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Solutions and Tools for Dealing with Broken Links in Web Pages

A couple of months ago a post by Leo Blanchette got to the front page of Hacker News and there was an interesting discussion on dealing with broken links and external content – the main problem being links that become out of date due to paywalls, altered content, or content getting taken down.

I’ve been running this blog since May 2008. If you’ve run a content-driven site for even a fraction of that, you know that link rot is a problem. In this post I’ll go over some of the suggestions in that thread along with some tools to use to check for broken links.

The post Solutions and Tools for Dealing with Broken Links in Web Pages appeared first on Impressive Webs.



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More 'dead' mobile services?




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Pictures from the dear departed




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​Weather gods: On ‘Mission Mausam’

Attempts at controlling the weather are still in the realm of uncertainty




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​Unrealistic expectations: On India and Russia-Ukraine peace

India’s efforts at peacemaking between Russia and Ukraine have limited potential




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Party on the move: On the Aam Aadmi Party, its leader

AAP’s Arvind Kejriwal continues to surprise, also outlining his political ambitions




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Staunch the breach: On India, Pakistan and the Indus Waters Treaty

India and Pakistan need to drop their hard line stances on the Indus Waters Treaty




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​Mad doctrine: On Russia’s revision of its nuclear doctrine

Any threat of use of nuclear weapons must be viewed seriously 




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​Steady but slow: On the VIPER mission, lessons for India

India’s space programme needs more resources to realise its full potential




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​Heartland murmurs: On the Haryana Assembly elections

Haryana may throw up surprises after the realignments




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​Healthy sign: On the voting in the 2024 J&K Assembly elections

Turnout numbers in the Assembly elections show distinct patterns in south Kashmir




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The other monsoon: On the northeast monsoon

Better modelling of the impact of northeast monsoon is essential




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A learning curve: On the PM Internship Scheme

The outcomes of the PM Internship Scheme’s pilot project need monitoring




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A defeat foretold: On the Maoist insurgency

Maoists must abandon armed struggle and enter the democratic process




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A Korean win: On the 2024 Nobel Prize in Literature

A Nobel raises Korean prose to success levels of its drama and music 




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​Sufferers, awarded: On the 2024 Nobel Peace Prize

The Nobel Peace for the selfless Nihon Hidankyo should help stir debates on nuclear disarmament




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​Over the borderline: On the India-China deal 

The agreement between India and China opens new opportunities  




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Cost of Games: On the 2026 Commonwealth Games 

Taking out popular sports from the CWG is a short-term solution 




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At a loss: On the New Zealand-India three-match series

India batters frittered away the home advantage against New Zealand 




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​Beautifully vague: On the Tamilaga Vettri Kazhagam’s inaugural conference  

Actor Vijay seems to be targeting both the BJP and the DMK 




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Sun signs: On extreme heat and Tamil Nadu’s policy decision

States should prepare to assist the vulnerable during extreme heat events




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Towards Europe: On the India visits by the leaders of Germany, Spain

India used visits by leaders of Germany and Spain to balance ties in Europe 




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Pathogenesis of Alzheimer's disease and therapeutic strategies involving traditional Chinese medicine

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00660G, Review Article
Shutang Li, Jinfei Yang
As research on AD has progressed, TCM and its active ingredients have increasingly played a crucial role in clinical treatment. This article summarizes extracts from TCM and briefly elucidates their pharmacological mechanisms against AD.
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Design, synthesis, inhibitory activity, and molecular simulations study for D-glucose-conjugated thioureas containing pyrimidine ring as multitarget inhibitors against α-amylase, α-glucosidase, DDP-4, and PTP1B in Type 2 diabetes mellitus

RSC Med. Chem., 2024, 15,3395-3417
DOI: 10.1039/D4MD00334A, Research Article
Vu Ngoc Toan, Do Son Hai, Hoang Thi Kim Van, Nguyen Minh Tri, Duong Ngoc Toan, Nguyen Thi Thanh Mai, Nguyen Dinh Thanh
D-Glucose-conjugated thioureas from 2-aminopyrimidines had inhibitory activity against α-amylase, α-glucosidase, DPP-4, PTP1B. The cytotoxicity, inhibitory kinetics, and molecular simulations of the most potent inhibitors 8k, 8j, 8f, and 8h were studied.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia

RSC Med. Chem., 2024, 15,3495-3506
DOI: 10.1039/D4MD00275J, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Thomas J. Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R. G. Galan, Morgan Jay-Smith, Kate S. Harris, Carole J. R. Bataille, Thomas R. Jackson, Douzi Zhang, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. Russell
The optimisation of a class of AML differentiation agents is described to show improved potency, solubility and stability, reduced off target toxicity, and tumour regression in a murine model in vivo.
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Semisynthetic phytochemicals in cancer treatment: a medicinal chemistry perspective

RSC Med. Chem., 2024, 15,3345-3370
DOI: 10.1039/D4MD00317A, Review Article
Meghna Arora, Ankit Kumar Singh, Adarsh Kumar, Harshwardhan Singh, Prateek Pathak, Maria Grishina, Jagat Pal Yadav, Amita Verma, Pradeep Kumar
Semisynthetic phytochemicals in cancer treatment.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Synthesis of a celastrol derivative as a cancer stem cell inhibitor through regulation of the STAT3 pathway for treatment of ovarian cancer

RSC Med. Chem., 2024, 15,3433-3443
DOI: 10.1039/D4MD00468J, Research Article
Meijuan Liu, Na Li, Zhaoxue Wang, Shuo Wang, Shaoda Ren, Xiaojing Li
A synthetic celastrol derivative (Cel-N) attenuates cancer cell stemness, inhibits the STAT3 pathway, and exerts anti-ovarian cancer effects in cell and mouse models.
The content of this RSS Feed (c) The Royal Society of Chemistry