c

Additively manufactured functionally graded biodegradable porous zinc

Biomater. Sci., 2020, 8,2404-2419
DOI: 10.1039/C9BM01904A, Paper
Open Access
Y. Li, P. Pavanram, J. Zhou, K. Lietaert, F. S. L. Bobbert, Yusuke Kubo, M. A. Leeflang, H. Jahr, A. A. Zadpoor
First report on the effect of topology design on the biodegradation, mechanical properties, and cell responses of additively manufactured Zn.
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Oral biofilm elimination by combining iron-based nanozymes and hydrogen peroxide-producing bacteria

Biomater. Sci., 2020, 8,2447-2458
DOI: 10.1039/C9BM01889A, Paper
Yanqiu Wang, Xinyu Shen, Shang Ma, Qianqian Guo, Wei Zhang, Lu Cheng, Liming Ding, Zhuobin Xu, Jing Jiang, Lizeng Gao
Combining nanozymes and bacteria to eliminate dental biofilms in a mixed-species model.
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Naturally available hypericin undergoes electron transfer for type I photodynamic and photothermal synergistic therapy

Biomater. Sci., 2020, 8,2481-2487
DOI: 10.1039/D0BM00021C, Paper
Zhen Ke, Aize Xie, Jianjiao Chen, Zhenyuan Zou, Lei Shen, Yansong Dai, Dengfeng Zou
Hypericin undergoing electron transfer can be used for type I PDT and PTT.
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In situ conversion of rose bengal microbubbles into nanoparticles for ultrasound imaging guided sonodynamic therapy with enhanced antitumor efficacy

Biomater. Sci., 2020, 8,2526-2536
DOI: 10.1039/C9BM02046B, Paper
Rui Hou, Xiaolong Liang, Xiaoda Li, Xu Zhang, Xiaotu Ma, Fan Wang
Sonosensitizer microbubbles enhance drug accumulation and the antitumor efficacy of sonodynamic therapy by ultrasound mediated micro to nano conversion.
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A riboflavin–ultraviolet light A-crosslinked decellularized heart valve for improved biomechanical properties, stability, and biocompatibility

Biomater. Sci., 2020, 8,2549-2563
DOI: 10.1039/C9BM01956A, Paper
Chungeng Liu, Weihua Qiao, Hong Cao, Jinchi Dai, Fei Li, Jiawei Shi, Nianguo Dong
Riboflavin–ultraviolet light A could effectively crosslink a decellularized heart valve to improve its biomechanical properties, stability and biocompatibility.
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Tumor localization of oncolytic adenovirus assisted by pH-degradable microgels with JQ1-mediated boosting replication and PD-L1 suppression for enhanced cancer therapy

Biomater. Sci., 2020, 8,2472-2480
DOI: 10.1039/D0BM00172D, Paper
Haishi Qiao, Xingmei Chen, Qiming Wang, Junmei Zhang, Dechun Huang, Enping Chen, Hongliang Qian, Yinan Zhong, Qi Tang, Wei Chen
Illustration of pH-degradable microgels (MGs) for the simultaneous encapsulation of OA and JQ1 for an enhanced oncolytic viral treatment with JQ1-meidated boosting viral replication and PD-L1 suppression.
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Trastuzumab targeted micellar delivery of docetaxel using dendron–polymer conjugates

Biomater. Sci., 2020, 8,2600-2610
DOI: 10.1039/C9BM01764J, Paper
Burcu Sumer Bolu, Bianka Golba, Amitav Sanyal, Rana Sanyal
Incorporation of a therapeutic antibody into nanosized drug delivery systems can improve their target specificity.
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Engineering red-emitting multi-functional nanocapsules for magnetic tumour targeting and imaging

Biomater. Sci., 2020, 8,2590-2599
DOI: 10.1039/D0BM00314J, Paper
Julie Tzu-Wen Wang, Umberto Martino, Rehan Khan, Maasoomeh Bazzar, Paul Southern, Dönüş Tuncel, Khuloud T. Al-Jamal
Self-red-emitting magnetic PLGA-PEG nanocapsules for optical imaging and magnetic tumour targeting.
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Biomimic strategies for modulating the interaction between particle adjuvants and antigen-presenting cells

Biomater. Sci., 2020, 8,2366-2375
DOI: 10.1039/C9BM02098E, Review Article
Jie Wu, Guanghui Ma
The design strategies of particle adjuvants by mimicking natural pathogens to strengthen their interaction with antigen-presenting cells.
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Dual-responsive click-crosslinked micelles designed for enhanced chemotherapy for solid tumors

Biomater. Sci., 2020, 8,2507-2513
DOI: 10.1039/D0BM00078G, Paper
Rong Jin, Jing Sun, Liefu Zhou, Xuelian Guo, Aoneng Cao
Core-crosslinked dual-responsive micelles can be readily constructed from a pair of clickable copolymers and applied for controlled release of anticancer drugs in cancer therapy.
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Super-assembled core/shell fibrous frameworks with dual growth factors for in situ cementum–ligament–bone complex regeneration

Biomater. Sci., 2020, 8,2459-2471
DOI: 10.1039/D0BM00102C, Paper
Tian Ding, Jianhua Li, Xingshuang Zhang, Lingqian Du, Yang Li, Dengwang Li, Biao Kong, Shaohua Ge
In this work, a super-assembled framework (SAF) was fabricated to achieve sequential delivery of bFGF and BMP-2 for in situ cementum–ligament–bone complex regeneration.
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A nanosystem loaded with perfluorohexane and rose bengal coupled upconversion nanoparticles for multimodal imaging and synergetic chemo-photodynamic therapy of cancer

Biomater. Sci., 2020, 8,2488-2506
DOI: 10.1039/C9BM02081K, Paper
Hai-yan Wang, Li Hou, Hai-liang Li, Xu Wang, Yang Cao, Bo-yu Zhang, Jing-tao Wang, Shi-jie Wei, Hong-wan Dang, Hai-tao Ran
A novel nanosystem (FURH-PFH-NPs) combined with LIFU and laser irradiation realized multimodal imaging, targeted release of HCPT, UCNPs-RB and synergetic chemo-photodynamic therapy of cancer.
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Enhanced selectivity, cellular uptake, and in vitro activity of an intrinsically fluorescent copper–tirapazamine nanocomplex for hypoxia targeted therapy in prostate cancer

Biomater. Sci., 2020, 8,2420-2433
DOI: 10.1039/C9BM01905G, Paper
Vera L. Silva, Abdessamad Kaassis, Ashkan Dehsorkhi, Cédrik-Roland Koffi, Maja Severic, Moustafa Abdelhamid, Duuamene Nyimanu, Christopher J. Morris, Wafa’ T. Al-Jamal
Cu(TPZ)2 complex as a promising hypoxia selective cytotoxin in prostate cancer.
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Bioinspired inorganic nanoparticles and vascular factor microenvironment directed neo-bone formation

Biomater. Sci., 2020, 8,2627-2637
DOI: 10.1039/D0BM00041H, Paper
Hwan D. Kim, Jungha Park, Sivashanmugam Amirthalingam, R. Jayakumar, Nathaniel S. Hwang
VEGF-overexpressing human tonsil-derived stem cells (VEGF-hTMSCs) and a whitlockite microenvironment induce vascularized bone tissue formation in biodegradable polymeric scaffolds.
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Assembly of FN-silk with laminin-521 to integrate hPSCs into a three-dimensional culture for neural differentiation

Biomater. Sci., 2020, 8,2514-2525
DOI: 10.1039/C9BM01624D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Carolina Åstrand, Veronique Chotteau, Anna Falk, My Hedhammar
The functionalized recombinant spider silk protein FN-silk can self-assemble into a 3D microfiber network. When combined with recombinant laminin521 it provides a 3D culture system suitable for expansion of hPSCs and following neural differentiation.
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A medical adhesive used in a wet environment by blending tannic acid and silk fibroin

Biomater. Sci., 2020, 8,2694-2701
DOI: 10.1039/D0BM00322K, Paper
Xijie Gao, Qiyuan Dai, Longtao Yao, Hua Dong, Qingtao Li, Xiaodong Cao
A medical adhesive called TASK based on polyphenol-gel systems was developed and showed wet-adhesive, stretchable, self-healing and restorable properties.
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Injectable hydrogel systems with multiple biophysical and biochemical cues for bone regeneration

Biomater. Sci., 2020, 8,2537-2548
DOI: 10.1039/D0BM00104J, Paper
Weinan Cheng, Zhaozhao Ding, Xin Zheng, Qiang Lu, Xiangdong Kong, Xiaozhong Zhou, Guozhong Lu, David L. Kaplan
Tunable multiple angiogenic and osteogenic cues were introduced into hydrogel systems simultaneously to optimize the niches for bone regeneration.
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NIR-emitting semiconducting polymer nanoparticles for in vivo two-photon vascular imaging

Biomater. Sci., 2020, 8,2666-2672
DOI: 10.1039/C9BM02063B, Paper
Xiao-Ting Gong, Wenguang Xie, Jing-Jing Cao, Shengxiang Zhang, Kanyi Pu, Hao-Li Zhang
A NIR-emitting TPF probe (NESPN) was prepared using semiconducting polymers and used for continuously monitoring the whole process of ischemic stroke and subsequent reperfusion. This work provides a new and versatile tool for vascular research and diagnosis of vascular diseases.
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Spatial immobilization of endogenous growth factors to control vascularization in bone tissue engineering

Biomater. Sci., 2020, 8,2577-2589
DOI: 10.1039/D0BM00087F, Paper
Marta R. Casanova, Catarina Oliveira, Emanuel M. Fernandes, Rui L. Reis, Tiago H. Silva, Albino Martins, Nuno M. Neves
An engineered biofunctional system comprises endogenous BMP-2 and VEGF bound in a parallel pattern. It successfully enabled obtaining the spatial osteogenic and angiogenic differentiation of human hBM-MSCs under basal culture conditions.
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H2S-releasing amphiphilic dipeptide hydrogels are potent S. aureus biofilm disruptors

Biomater. Sci., 2020, 8,2564-2576
DOI: 10.1039/D0BM00241K, Paper
Yun Qian, Afnan Altamimi, Shaina Alston Yates, Santu Sarkar, Matthew Cochran, Mingjun Zhou, Nicole Levi-Polyachenko, John B. Matson
Hydrogen sulfide (H2S) is an endogenous signaling gas, and exogenous H2S administration has the potential for promoting wound healing. Here we investigate the antimicrobial effects of H2S-releasing hydrogels in the context of burn wound healing.
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Nanomedicine – a promising therapy for hematological malignancies

Biomater. Sci., 2020, 8,2376-2393
DOI: 10.1039/D0BM00129E, Review Article
Lifen Huang, Jun Huang, Junbin Huang, Hongman Xue, Zhiqing Liang, Jun Wu, Chun Chen
Nanoparticles (NPs) are used for the diagnosis and treatment of hematological tumors by loading various pharmacodynamic molecules.
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A thermo-responsive, self-assembling biointerface for on demand release of surface-immobilised proteins

Biomater. Sci., 2020, 8,2673-2681
DOI: 10.1039/C9BM01957J, Paper
Angela Saccardo, Mikhail Soloviev, Enrico Ferrari
Engineering of the neuronal SNARE proteins yields chimeric bio-materials that reversibly assemble and disassemble at set temperatures.
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The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells

Biomater. Sci., 2020, 8,2611-2626
DOI: 10.1039/C9BM01965K, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
F. A. A. Ruiter, L. E. Sidney, K. L. Kiick, J. I. Segal, C. Alexander, F. R. A. J. Rose
The fabrication and application of a biocompatible peptide conjugated thermo-responsive fibrous scaffolds for cellular phenotype support and enzymatic-free passaging of mammalian cells.
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Highly responsive and rapid hydrogen peroxide-triggered degradation of polycaprolactone nanoparticles

Biomater. Sci., 2020, 8,2394-2397
DOI: 10.1039/C9BM02019E, Communication
Peng-Hao Hsu, Carina Arboleda, Alexandra Stubelius, Ling-Wei Li, Jason Olejniczak, Adah Almutairi
Nanoparticles formulated from fast-degrading oxidation-responsive polycaprolactone are responsive to 50 μM of H2O2.
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Topography induced stiffness alteration of stem cells influences osteogenic differentiation

Biomater. Sci., 2020, 8,2638-2652
DOI: 10.1039/D0BM00264J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Liangliang Yang, Qi Gao, Lu Ge, Qihui Zhou, Eliza M. Warszawik, Reinier Bron, King Wai Chiu Lai, Patrick van Rijn
Topography-driven alterations to single cell stiffness rather than alterations in cell morphology, is the underlying driver for influencing cell biological processes, particularly stem cell differentiation.
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Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis

Biomater. Sci., 2020, 8,2653-2665
DOI: 10.1039/D0BM00140F, Paper
Amit G. Krishnan, Raja Biswas, Deepthy Menon, Manitha B. Nair
The study shows the development of a biodegradable bi-functional composite scaffold that can reduce bacterial infection, while promotes bone regeneration in osteomyelitis, without the need for revision surgery.
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Advances in living cell-based anticancer therapeutics

Biomater. Sci., 2020, 8,2344-2365
DOI: 10.1039/D0BM00036A, Review Article
He Dong, Xiao Xu, Leikun Wang, Ran Mo
This review summarizes recent advances in the applications of living cells as drug carriers or active drugs for anticancer drug delivery and cancer therapy.
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Interfacing human induced pluripotent stem cell-derived neurons with designed nanowire arrays as a future platform for medical applications

Biomater. Sci., 2020, 8,2434-2446
DOI: 10.1039/D0BM00182A, Paper
Jann Harberts, Undine Haferkamp, Stefanie Haugg, Cornelius Fendler, Dennis Lam, Robert Zierold, Ole Pless, Robert H. Blick
Nanostructured substrates such as nanowire arrays form a powerful tool for building next-generation medical devices.
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A novel peptide targeting gastrin releasing peptide receptor for pancreatic neoplasm detection

Biomater. Sci., 2020, 8,2682-2693
DOI: 10.1039/D0BM00162G, Paper
Yuanbiao Tu, Ji Tao, Fang Wang, Peifei Liu, Zhihao Han, Zhaolun Li, Yi Ma, Yueqing Gu
The designed novel peptide GB-6 with targeted GRPR-binding possesses more favorable pharmacokinetic properties and metabolic stability, as well as superior tumor-targeting ability in pancreatic cancer models, relative to BBN7–14.
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Particle-mediated delivery of frataxin plasmid to a human sensory neuronal model of Friedreich's ataxia

Biomater. Sci., 2020, 8,2398-2403
DOI: 10.1039/C9BM01757G, Communication
Ewa Czuba-Wojnilowicz, Serena Viventi, Sara E. Howden, Simon Maksour, Amy E. Hulme, Christina Cortez-Jugo, Mirella Dottori, Frank Caruso
Multilayered particles in gene therapy for Friedreich's ataxia induce a 27 000-fold increase in frataxin gene expression in a patient-derived cell model.
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An intelligent vancomycin release system for preventing surgical site infections of bone tissues

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00255K, Paper
Yuan Li, Guang Li, Xiaoling Sha, Litao Li, Kuo Zhang, Daohong Liu, Yanfei Hao, Xu Cui, Lei Wang, Hao Wang
An intelligent anti-bacterial system can be constructed on implants during surgery.
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Outstanding Reviewers for Biomaterials Science in 2019

Biomater. Sci., 2020, 8,2343-2343
DOI: 10.1039/D0BM90031A, Editorial

We would like to take this opportunity to highlight the Outstanding Reviewers for Biomaterials Science in 2019, as selected by the editorial team for their significant contribution to the journal.
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A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00425A, Paper
Kun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong Wang
A universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.
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Modulating neutrophil extracellular traps for wound healing

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00355G, Paper
Tejinder Kaur, Shweta Dumoga, Veena Koul, Neetu Singh
An alginate-GelMa scaffold for modulating neutrophil extracellular traps using a PAD4 inhibitor could be a novel therapeutic approach for wound healing.
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A super-stretchable, self-healing and injectable supramolecular hydrogel constructed by a host–guest crosslinker

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00290A, Paper
Yang Zhou, Yuanhao Zhang, Zhaobo Dai, Fang Jiang, Jia Tian, Weian Zhang
Supramolecular hydrogels based on host–guest interactions have drawn considerable attention due to their unique properties and promising applications.
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A versatile ultrafine and super-absorptive H+-modified montmorillonite: application for metabolic syndrome intervention and gastric mucosal protection

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00474J, Paper
Qiwen Wang, Jie Shen, Enqi Mo, Haotian Zhang, Jianwei Wang, Xiurong Hu, Jun Zhou, Hongzhen Bai, Guping Tang
An H+-modified montmorillonite (H-MMT) was prepared using an acid modification method to obtain powerful absorption ability as a theranostic platform for both metabolic syndrome and gastric mucosa protection.
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Coupling PEG-LZM Polymer Network with Polyphenol Yields Suturable Biohydrogel for Tissue Patching

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00429D, Paper
Haoqi Tan, Junjie Sun, Dawei Jin, Jialin Song, Miao Lei, Artem Antoshin, Xin Chen, Meng Yin, Xue Qu, Changsheng Liu
Poor mechanical performances severely limit the application of hydrogel in vivo, for example, it is difficult to perform a very common suturing operation on hydrogel during surgery. There is a...
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Optically controlled hybrid metamaterial of plasmonic spiky gold inbuilt graphene sheets for bimodal imaging guided multimodal therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00312C, Paper
Kunnumpurathu Jibin, Jayaram S. Prasad, Giridharan Saranya, Sachin J. Shenoy, Kaustabh K. Maiti, Ramapurath S. Jayasree
Gold–graphene nanohybrid for simultaneous dual-imaging guided triple therapy as a new paradigm in light-triggered cancer theranostics. The material demonstrates excellent therapeutic efficacy and treatment monitoring features.
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A transport system based on a quantum dot-modified nanotracer is genetically and developmentally stable in pregnant mice

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00311E, Paper
Open Access
Hye Jin Kim, Ji Sun Park, Se Won Yi, Minyeon Go, Hye-Ryun Kim, Su Jin Lee, Jong Min Park, Dong Hyun Cha, Sung Han Shim, Keun-Hong Park
The use of nanoscale materials (NMs) could cause problems such as cytotoxicity, genomic aberration, but the impacts of NM exposure during pregnancy remain uncharacterized in the context of clinical applications.
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Surface engineering of titanium alloy using metal-polyphenol network coating with magnesium ions for improved osseointegration

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00566E, Paper
Sangmin Lee, Yun-Young Chang, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Yang-Hun Jung, Jeong-Ho Yun, Heungsoo Shin
Although titanium-based implants are widely used in orthopedic and dental clinics, improved osseointegration at the bone–implant interface is still required.
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A biomimetic orally targeted delivery of Bindarit for immunotherapy of atherosclerosis

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00418A, Paper
Luqi Yin, Cuiping Peng, Yue Tang, Yuchuan Yuan, Jiaxing Liu, Tingting Xiang, Feila Liu, Zhou Xing, Xiaohui Li
Monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of atherosclerosis. However, the application of bindarit (a specific synthetic inhibitor of MCP-1) in atherosclerosis has not been confirmed...
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Functionalized Biomaterials to Combat Biofilm

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00526F, Minireview
Dan-ni Huang, Jing Wang, Kefeng Ren, Jian Ji
Pathogenic microbial biofilms readily form on implantable medical devices or human tissues have posed a great threat to worldwide healthcare. Hopes are focused on preventive strategies of biofilms, leaving a...
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Effective intracellular delivery of bevacizumab via PEGylated polymeric nanoparticles targeting CD44v6 receptor in colon cancer cells

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00556H, Paper
Ana Baião, Flávia Sousa, Ana Oliveira, Carla Oliveira, Bruno Sarmento
Colorectal cancer (CRC) is one of the most incident and mortal cancers in the world, mainly due to its metastatic and metabolic ability. CD44 receptor isoform containing exon 6 (CD44v6)...
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SciVal.

Location World Wide Web
Call No. LB2341.98




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Serum miRNAs are differentially altered by ethanol and caffeine consumption in rats

Toxicol. Res., 2019, 8,842-849
DOI: 10.1039/C9TX00069K, Paper
M. Martinez, I. M. U. Rossetto, R. M. S. Arantes, F. S. N. Lizarte, L. F. Tirapelli, D. P. C. Tirapelli, L. G. A. Chuffa, F. E. Martinez
Alcoholism is a multifactorial disease with high risk for dependence determined by genetic background, environmental factors and neuroadaptations.
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Prometryn induces apoptotic cell death through cell cycle arrest and oxidative DNA damage

Toxicol. Res., 2019, 8,833-841
DOI: 10.1039/C9TX00080A, Paper
Qiaoyun Liu, Longsheng Wang, Hanwen Chen, Bo Huang, Jiawei Xu, Ying Li, Paul Héroux, Xinqiang Zhu, Yihua Wu, Dajing Xia
Prometryn induces oxidative stress-mediated DNA damage; Prometryn induces S phase of cell cycle arrest; Prometryn induces Bax-dependent apoptosis in BEAS-2B cells.
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Integrated network pharmacology and targeted metabolomics to reveal the mechanism of nephrotoxicity of triptolide

Toxicol. Res., 2019, 8,850-861
DOI: 10.1039/C9TX00067D, Paper
Wei Huang, Chuanxin Liu, Lijuan Xie, Yuming Wang, Yanyan Xu, Yubo Li
Integrated network pharmacology and targeted metabolomics to reveal the nephrotoxicity mechanism of triptolide.
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Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese hamster ovary cells

Toxicol. Res., 2019, 8,868-874
DOI: 10.1039/C9TX00113A, Paper
Neo Mervyn Monaheng, Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel Oluwafemi
In this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay.
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Tin thiocarbonohydrazone complexes: synthesis, crystal structures and biological evaluation

Toxicol. Res., 2019, 8,862-867
DOI: 10.1039/C9TX00109C, Paper
Jin Wang, Yu-Ting Wang, Yan Fang, Yan-Li Lu, Ming-Xue Li
Three organotin thiocarbonohydrazone complexes have been synthesized, and growth inhibition assays indicated that complex 3 has the highest tumor cell selectivity.
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miR-140-5p mediates bevacizumab-induced cytotoxicity to cardiomyocytes by targeting the VEGFA/14-3-3γ signal pathway

Toxicol. Res., 2019, 8,875-884
DOI: 10.1039/C9TX00100J, Paper
Xuan-Ying Chen, Wei-Lin Huang, Xiao-Ping Peng, Yan-Ni Lv, Jun-He Li, Jian-Ping Xiong
Bevacizumab (BVZ) is a widely investigated angiogenesis inhibitor in cancer patients. Although the anti-tumor effects has been verified, cardiotoxicity may be the most serious side-effect for BVZ.
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