c Kaempferol derivatives isolated from Lens culinaris Medik. reduce DNA damage induced by etoposide in peripheral blood mononuclear cells By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,896-907DOI: 10.1039/C9TX00176J, PaperMagdalena Kluska, Michał Juszczak, Daniel Wysokiński, Jerzy Żuchowski, Anna Stochmal, Katarzyna WoźniakBioactive compounds isolated from plants are considered to be attractive candidates for cancer therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use” by D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489 By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1057-1058DOI: 10.1039/C9TX00158A, CommentMichael E. Mullins, Mark C. Yarema, Marco L. A. Sivilotti, Margaret Thompson, D. Adam Algren, Michael C. Beuhler, Christopher P. HolstegeWe point out an acetylcysteine protocol that a previous article (D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489–498) overlooked.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Characteristic synergistic cytotoxic effects toward cells in graphene oxide dressing with cadmium and copper ions By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,908-917DOI: 10.1039/C9TX00146H, PaperYiyang Dong, Yulin Chang, Haidi Gao, Victoria Arantza León Anchustegui, Qiang Yu, Haifang Wang, Jia-Hui Liu, Shihui WangCadmium ions exerted synergistic toxic effects with graphene oxide on Hela cells.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Ex vivo toxicological evaluation of experimental anticancer gold(I) complexes with lansoprazole-type ligands By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,885-895DOI: 10.1039/C9TX00149B, PaperNatalia Estrada-Ortiz, Elena Lopez-Gonzales, Ben Woods, Stefan Stürup, Inge A. M. de Graaf, Geny M. M. Groothuis, Angela CasiniNovel experimental anticancer gold-based compounds were studied for their mechanisms of toxicity in healthy rat kidney and liver tissues, using the Precision Cut Tissue Slices (PCTS) technique.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Gynura divaricata ameliorates hepatic insulin resistance by modulating insulin signalling, maintaining glycolipid homeostasis and reducing inflammation in type 2 diabetic mice By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,928-938DOI: 10.1039/C9TX00191C, PaperXuan Dong, Shu-Xiang Zhao, Bing-Qing Xu, Yu-Qing ZhangOral lyophilized powder of Gynura divaricata, an edible medicinal plant, can alleviate both hyperglycaemia and hepatic insulin resistance in type 2 diabetic mice.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Lipoic acid antagonizes paraquat-induced vascular endothelial dysfunction by suppressing mitochondrial reactive oxidative stress By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,918-927DOI: 10.1039/C9TX00186G, PaperLi Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhouα-Lipoic acid antagonizes paraquat toxicity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Thyroid endocrine status and biochemical stress responses in adult male Wistar rats chronically exposed to pristine polystyrene nanoplastics By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,953-963DOI: 10.1039/C9TX00147F, PaperFatemeh Amereh, Akbar Eslami, Simin Fazelipour, Mohammad Rafiee, Mohammad Ismail Zibaii, Mohammad BabaeiAt this time, little is known about the long-term effects of micro(nano)plastics on public health. In the present study, early warning signs of thyroid endocrine disruption were noticed in adult Wistar rats from the ingestion of virgin polystyrene nanoparticles.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Environmental distribution of the neurotoxin L-BMAA in Paenibacillus species By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,781-783DOI: 10.1039/C9TX00203K, ViewpointPeter B. Nunn, Geoffrey A. CoddThe neurotoxic amino acid, 3-N-methyl-2,3-diaminopropanoic acid (BMAA), known in plants of the genus Cycas and in aquatic cyanobacteria and other organisms, is a component of antibiotic peptides in two species of Paenibacillus.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Reply to the ‘Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use”’ by M. E. Mullins, M. C. Yarema, M. L. A. Sivilotti, M. Thompson, D. A. Algren, M. C. Beuhler and C. P. Holstege, Toxicol. Res., 2019, 8, DOI: 10.1039/C9T By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1059-1059DOI: 10.1039/C9TX00216B, Comment Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.D. Nicholas Bateman, James W. DearMullins et al. made a comment on our article (DOI: 10.1039/C9TX00002J) stating they noticed the omission of the one-bag, standard concentration protocol which is shared by several centers in North America when we discussed IV acetylcysteine protocols.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Biogenic Aspergillus tubingensis silver nanoparticles’ in vitro effects on human umbilical vein endothelial cells, normal human fibroblasts, HEPG2, and Galleria mellonella By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,789-801DOI: 10.1039/C9TX00091G, PaperCristiane Angélica Ottoni, Durvanei Augusto Maria, Priscila Jane Romano de Oliveira Gonçalves, Welington Luiz de Araújo, Ana Olívia de SouzaBiogenic silver nanoparticles are ecofriendly and offers valuable possibilities of applications in several industrial areas.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Cadmium telluride quantum dot-exposed human bronchial epithelial cells: a further study of the cellular response by proteomics By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,994-1001DOI: 10.1039/C9TX00126C, PaperYan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. LauA comparative proteome analysis was conducted to identify global changes in the protein expression profiles of cadmium telluride quantum dot-exposed human bronchial epithelial BEAS-2B cells.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Synergistic antioxidant capacity of CsNPs and CurNPs against cytotoxicity, genotoxicity and pro-inflammatory mediators induced by hydroxyapatite nanoparticles in male rats By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,939-952DOI: 10.1039/C9TX00221A, PaperIsraa F. Mosa, Mokhtar Youssef, Maher Kamel, Osama F. Mosa, Yasser HelmyDue to their dynamic characteristics, hydroxyapatite nanoparticles (HAP-NPs) have been employed numerous times in nanomedicine and in tissue engineering, particularly as diagnostic and therapeutic agents.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Innovative models for in vitro detection of seizure By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,784-788DOI: 10.1039/C9TX00210C, Review ArticleKimberly L. Rockley, Ruth A. Roberts, Michael J. MortonNew technologies offer the opportunity to screen for seizure liability in vitro, avoiding costly failures in preclinical and clinical development.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Novel evaluation of sevoflurane anesthetic exposure on the testicular germ cells of neonatal male mice By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,988-993DOI: 10.1039/C9TX00193J, PaperAli Raza Ebrahim Soltani, Abdolmohammad Kajbafzadeh, Maryam Ezzati, Zahra Ebrahim Soltani, Navid Hosseinifar, Anahid Maleki, Maryam Nezhad SistaniInhalatory anesthetics may impact spermatogenesis and sexual behavior.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Cigarette smoke inhalation aggravates diabetic kidney injury in rats By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,964-971DOI: 10.1039/C9TX00201D, PaperSongling Jiang, Do Van Quan, Jae Hyuck Sung, Moo-Yeol Lee, Hunjoo HaFour weeks of exposure to cigarette smoke aggravated the progression of diabetic kidney injury including inflammation, fibrosis, and oxidative stress.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Mice with a Sertoli cell-specific knockout of the Ctr1 gene exhibit a reduced sensitivity to cisplatin-induced testicular germ cell apoptosis By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,972-978DOI: 10.1039/C9TX00142E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Rashin Ghaffari, John H. RichburgExposure to the chemotherapeutic agent cis-diamminedichloroplatinum(II) (cDDP) is well known to instigate acute and prolonged testicular injury in male patients.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Effects of moderate red wine on cardiovascular risk factors in diabetics: a systematic review and meta-analysis of randomized controlled trials By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,979-987DOI: 10.1039/C9TX00227H, PaperSaavia Alice Naame, Decheng Li, Ruixue HuangDiabetes mellitus is of major public health concerns; its incidence is continuously increasing.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Methanol extract of Iphiona aucheri ameliorates CCl4 induced hepatic injuries by regulation of genes in rats By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,815-832DOI: 10.1039/C9TX00157C, PaperJawaid Ahmed Zai, Muhammad Rashid Khan, Zaib un Nisa Mughal, Riffat Batool, Irum Naz, Sonia Maryam, Zartash ZahraAlteration in expression of ER stress associated genes, inflammatory genes and antioxidant biochemical induced with CCl4 in liver of rats were restored towards the control rats by co-administration of methanol extract of Iphiona aucheri to rats.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Astilbin attenuates cerebral ischemia/reperfusion injury by inhibiting the TLR4/MyD88/NF-κB pathway By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1002-1008DOI: 10.1039/C9TX00222G, PaperJing Li, Zhaowei Gu, Yue Liu, Yu Wang, Min ZhaoIschemic stroke is the second most common cause of death worldwide and cerebral ischemia/reperfusion (I/R) injury also leads to serious tissue damage.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Astaxanthin reduces perfluorooctanoic acid cytotoxicity in Saccharomyces cerevisiae By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1009-1015DOI: 10.1039/C9TX00215D, PaperS. J. Sudharshan, Raghavendra Tirupathi, Madhu DyavaiahPerfluorooctanoic acid (PFA) has been identified as an environmental contaminant of high concern for human health.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Nanoparticle induced barrier function assessment at liquid–liquid and air–liquid interface in novel human lung epithelia cell lines By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1016-1027DOI: 10.1039/C9TX00179D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lars Leibrock, Sandra Wagener, Ajay Vikram Singh, Peter Laux, Andreas LuchTo answer questions about nanoparticle toxicity, translocation and biokinetics following inhalation exposure, in vitro models should have functional barrier properties to mimic the in vivo situation as closely as possible.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Application of the direct peptide reactivity assay (DPRA) to inorganic compounds: a case study of platinum species By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,802-814DOI: 10.1039/C9TX00242A, PaperJocelyn D. C. Hemming, Mark Hosford, Martin M. ShaferThe in chemico Direct Peptide Reactivity Assay (DPRA) was developed as a non-animal, relatively high throughput, screening tool for skin sensitization potential.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Phytochemicals protect L02 cells against hepatotoxicity induced by emodin via the Nrf2 signaling pathway By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1028-1034DOI: 10.1039/C9TX00220K, PaperYan Yan, Kang Wang, Xu Tang, Jun-feng Gao, Bin-yu WenDihydromyricetin (DMY), hyperoside and silybin are phytochemicals that belong to a class called flavonoids, and they have been used in liver protection pharmaceutical preparations, but the specific mechanism of these chemicals is still unclarified.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Benzoquinone alters the lipid homeostasis in Saccharomyces cerevisiae By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1035-1041DOI: 10.1039/C9TX00139E, PaperAbhishek Raj, Vasanthi NachiappanBQ exposure inhibited cell growth, increased the ROS-mediated apoptosis, and altered the phospholipids that resulted in membrane proliferation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Cytotoxic effect of silica nanoparticles against hepatocellular carcinoma cells through necroptosis induction By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1042-1049DOI: 10.1039/C9TX00240E, PaperYuexiang Niu, Engong Tang, Qingan ZhangHepatocellular carcinoma (HCC) is a common cancer that affects people worldwide with high morbidity and mortality, and its resistance to current chemotherapeutic drugs is a serious concern.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c The protective effect of thymoquinone on tert-butylhydroquinone induced cytotoxicity in human umbilical vein endothelial cells By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1050-1056DOI: 10.1039/C9TX00235A, PaperZahra Karimi, Maryam Ghaffari, Jafar Ezzati Nazhad Dolatabadi, Parvin Dehghan2-tert-Butyl-4-hydroquinone (TBHQ) is used for inhibition of oxidative rancidity in the food industry.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
c Central Board of Direct Taxes amends Rule 44G of Income-tax Rules 1962 By www.business-standard.com Published On :: Fri, 08 May 2020 10:34:00 +0530 It also states that if a resolution is arrived, the same shall be communicated to the assessee, who shall communicate his acceptance or non-acceptance within 30 days Full Article
c AIIB extends $500 mn loan to India to deal with coronavirus crisis By www.business-standard.com Published On :: Fri, 08 May 2020 10:44:00 +0530 The bank's board of directors has approved a loan to India to strengthen the preparedness of the country's national health system Full Article
c India's credit profile to face further pressure due to Covid-19: Moody's By www.business-standard.com Published On :: Fri, 08 May 2020 10:44:00 +0530 Moody's rating on the government of India is Baa2 with negative outlook Full Article
c Franklin Templeton issues apology to Sebi for global chief's remarks By www.business-standard.com Published On :: Fri, 08 May 2020 11:13:00 +0530 Stung by the comments made by the global chief, market regulator on Thursday issued a press release defending the new rules it introduced in October last year Full Article
c SC's struggles with 'unruly horse' of public policy in foreign awards By www.business-standard.com Published On :: Fri, 08 May 2020 11:58:00 +0530 The Nafed-Alimenta judgment shows it might perhaps be time for Parliament to intervene and clarify the notion of public policy in the context of foreign arbitral awards Full Article
c US Federal Reserve won't take rates negative, say fund managers, economists By www.business-standard.com Published On :: Fri, 08 May 2020 13:40:00 +0530 Fed funds futures, which are a gauge of where markets expect the Fed's benchmark overnight lending rate to be, are now pricing in a slightly negative rate environment beginning in December Full Article
c Nomura predicts Indian GDP to contract by 5.2% in FY21, more rate cuts By www.business-standard.com Published On :: Fri, 08 May 2020 14:36:00 +0530 Analysts at Goldman Sachs expect the Indian economy to contract 0.4 per cent in FY21 versus consensus median 2.7 per cent Full Article
c Only 13% of industrial units resume ops after Odisha eases lockdown By www.business-standard.com Published On :: Fri, 08 May 2020 17:29:00 +0530 Micro units in the state have not been able to resume operations to catch up with their larger peers Full Article
c Export contraction in April could surpass March's steep 25-year decline By www.business-standard.com Published On :: Fri, 08 May 2020 19:02:00 +0530 Major forex earning sectors cite lack of labour, funds and key supplies Full Article
c Vizag gas leak: NGT orders LG Polymers to deposit Rs 50 cr pending probe By www.business-standard.com Published On :: Fri, 08 May 2020 20:07:00 +0530 NGT bench set up fact-finding committee, to be headed by former AP High Court judge Full Article
c Gujarat eases labour laws, offers land to firms shifting base from China By www.business-standard.com Published On :: Fri, 08 May 2020 20:28:00 +0530 The state government also offered land and infrastructure for companies and projects that were looking to shift base from China to other destinations Full Article
c CBDT orders tax officials to not issue scrutiny notices to taxpayers By www.business-standard.com Published On :: Fri, 08 May 2020 20:29:00 +0530 Move comes after a group of IRS created panic and tax policy uncertainty Full Article
c Govt must work to revive consumption, not worry about rating: Rahul Gandhi By www.business-standard.com Published On :: Fri, 08 May 2020 20:44:00 +0530 Congress wants lockdown lifted across country on May 18, save hotspots; Gandhi urges Centre to make citizens 'psychologically' prepared to for lockdown exit Full Article
c Govt hikes borrowing limit by over 50% to Rs 12 trn as virus grips economy By www.business-standard.com Published On :: Fri, 08 May 2020 20:56:00 +0530 Sources say the Centre has asked RBI to do whatever to keep yields in check, which may result in massive secondary market bond purchases Full Article
c Country's first round-the-clock solar power tender closes at Rs 2.9/unit By www.business-standard.com Published On :: Fri, 08 May 2020 21:22:00 +0530 The project developer will have the option of building a hybrid plant with wind and hydro power or have energy storage systems Full Article
c HC orders closure of Liquor shops in Tamil Nadu, allows online sales By www.business-standard.com Published On :: Fri, 08 May 2020 22:48:00 +0530 The opening of shops in districts, except Chennai on May 7, has resulted in people thronging the outlets without maintaining social distancing norms Full Article
c Lockdown period not to be counted for determining residency of NRIs: CBDT By www.business-standard.com Published On :: Fri, 08 May 2020 23:12:00 +0530 There were apprehensions that this extended stay could lead to these individuals becoming Indian residents as per Section 6 of the Income Tax Act Full Article
c Working closely with states on labour reforms to help industry: Centre By www.business-standard.com Published On :: Fri, 08 May 2020 23:24:00 +0530 The Confederation of Indian Industry (CII) suggested to the Labour Ministry to "direct workers to join back to their workplace" by issuing a circular Full Article
c Covid-19 lockdown effect: Every second Indian now on internet in cities By www.business-standard.com Published On :: Fri, 08 May 2020 23:33:00 +0530 The data released by Nielsen and the Broadcast Audience Research Council (BARC) shows that internet usage has grown sharply in cities over the last one month, touching 54 per cent Full Article
c Additional borrowing to widen fiscal deficit, but help govt perk up economy By www.business-standard.com Published On :: Fri, 08 May 2020 23:50:00 +0530 He did not think that the move will crowd out borrowings of the private sector, saying demand of the government and the private sector are not contradictory in these circumstances Full Article
c FM to discuss credit flow to NBFCs, businesses with banks on Monday By www.business-standard.com Published On :: Sat, 09 May 2020 00:00:00 +0530 The FM will take stock of the credit sanction and disbursement by the banks since March 1, 2020, and the Covid-19-related emergency credit lines opened by the lenders Full Article
c Sitharaman launches two exchanges to take on offshore currency market By www.business-standard.com Published On :: Sat, 09 May 2020 00:20:00 +0530 The launch comes amid the world's most expansive coronavirus lockdown, which has crippled businesses and hurt trading volumes in the country's financial markets. Full Article
c Covid-19: Relief for NRIs, foreign visitors as tax residency rules eased By www.business-standard.com Published On :: Sat, 09 May 2020 02:08:00 +0530 The government imposed a lockdown on March 24 and is yet to open up travel, including international flights. Full Article
c Ministry of Defence inks Rs 1,200 cr contract to boost electronics sector By www.business-standard.com Published On :: Sat, 09 May 2020 02:23:00 +0530 The deal, Modernisation of Air Field Infrastructure Phase 2 (MAFI-2), follows from an earlier contract, called MAFI-1, which TPSED won in 2011 to upgrade 30 IAF airfields. Full Article