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Nanoparticle’s shape is the game-changer for blood-brain barrier crossing and delivering through tunneling nanotubes among glioblastoma cells.

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03174A, Paper
Open Access
Giulia Sierri, Ines Saenz-de-Santa-Maria, Antonio Renda, Marcus Koch, Patrizia Sommi, Umberto Anselmi-Tamburini, Mario Mauri, Alessia D'Aloia, Michela Ceriani, Domenico Salerno, FRANCESCO MANTEGAZZA, Chiara Zurzolo, Francesca Re
Tunneling Nanotubes (TNTs) are thin, dynamic, long membrane protrusions that allow the intercellular exchanges of signal clues, molecules and organelles. The presence of TNTs and their involvement as drug delivery...
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Synthesis, Characterization, Genotoxicity Assessment and Antibacterial Applications of Zanthoxylum armatum Silver Nanoparticles (ZASNP) with Antibiotic Efficacy Enhancement Potential

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03608E, Paper
Open Access
Nikita Quadri, Manjunath M. Setty, Anshumali Awasthi, Usha Yogendra Nayak, Minakshi Singh, Sharad Sharma
The study aimed to develop alternative antibacterial treatments by combining traditional herbal knowledge with modern nanotechnology. This approach targets multiple bacterial strains, combats antibiotic resistance, and offers solutions for treating...
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A liposome-based assay for cancer biomarker detection: exploring the correlation between platelet-derived microvesicles and NSCLC-associated miRNAs

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03704A, Paper
Mohamed Aimene Benariba, Kanza Hannachi, Sha Zhu, Yuting Zhang, Xiaoli Wang, Nandi Zhou
This research reveals a significant correlation between PMVs and their associated miRNA. Additionally, the liposome-based assay demonstrates enhanced sensitivity with calcium-induced platelet activation.
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Photo-Assisted Epitaxial Growth from Nanoparticles to Enhance Multi-Materialization for Advanced Surface Functionalization

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03112A, Paper
Masayuki Fukuda, Yuuki Kitanaka, Tomohiko Nakajima
To meet the requirements of freeform objects, a wide range of highly designable resin-based materials has been created, highlighting the need for low-temperature ceramic deposition methods for surface functionalization. Photo-assisted...
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Unraveling the Ammonia Sensing Behavior and Degradation Pathways of Novel Lead-Free MA2CuBr4 based Ammonia Sensor

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR02943G, Communication
Abinash Tiwari, Arjumand Mir, Aswani Yella
We report a lead-free copper-based halide perovskite gas sensor to detect ammonia gas at ambient temperature. The sensor uses methylammonium copper bromide as the active material and can trace ammonia...
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Exploring Graphene's Impact on Graphite/PANI Matrix Composites: High-Press Fabrication and Enhanced Thermal-Electrical Properties

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03171G, Paper
Murat OZLEK, Merve Sehnaz Akbulut, Engin Burgaz
This study investigates the effects of graphene content and applied press on electrical and thermal conductivities of graphite/polyaniline (GP) and graphite/graphene/polyaniline (GGP) composites which were produced by using direct mixing...
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Electrode Informatics Accelerated Optimization for Catalyst Layer Key Parameters in Direct Methanol Fuel Cells

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03026E, Paper
Lishou Ban, Danyang Huang, Yanyi Liu, Pengcheng Liu, Xihui Bian, Kaili Wang, Yifan Liu, Xijun Liu, Jia He
As the core component of direct methanol fuel cell, the catalyst layer plays the key role of material, proton and electron transport channels. However, due to the complexity of its...
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Emerging chiral sulfur-based nanomaterials for chiroptical applications

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03736G, Review Article
Hammad Hasan, Md Ifzal Azhar, Santosh Kumar Behera, Md Palashuddin Sk
This review covers fundamental principles and techniques for measuring chiral properties as well as the synthesis of chiral sulfur-based nanomaterials, their optical and chiroptical properties, and possible applications.
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Effect of number ratio and size ratio on the formation of binary superlattices assembled by two-sized polymer-tethered spherical nanoparticles

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR04032E, Communication
Open Access
Jinlan Li, Xin Yu, Jianing Zhang, Jing Jin, Yanxiong Pan, Xiangling Ji, Wei Jiang
Binary superlattices (BNSLs) with unique configurations are of great interest, attributing to the interaction between two kinds of nanoparticles, providing potential applications in sensing, electronic and optical fields. Here, polystyrene...
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Aptamer-functionalized Nucleic Acid Nanotechnology for Biosensing, Bioimaging and Cancer Therapy

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR04360J, Review Article
Xiaofang Zheng, Zhiyong Huang, Qiang Zhang, Guoli Li, Minghui Song, Ruizi Peng
Nucleic acids have enabled to fabricate self-assemblies and perform dynamic operations. Among different functional nucleic acids, aptamers can specifically bind to wide range of targets including proteins, viral antigens, living...
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Expression of concern: Iron oxide magnetic nanoparticles with versatile surface functions based on dopamine anchors

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR90209B, Expression of Concern
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Mykola Mazur, Alexandre Barras, Victor Kuncser, Andrei Galatanu, Vladimir Zaitzev, Kostiantyn V. Turcheniuk, Patrice Woisel, Joel Lyskawa, William Laure, Aloysius Siriwardena, Rabah Boukherroub, Sabine Szunerits
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Theoretical Understanding of the In-plane Tensile Strain Effects on Enhancing the Ferroelectric Performance of Hf0.5Zr0.5O2 and ZrO2 Thin Films

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03333G, Paper
Kun Hee Ye, Taeyoung Jeong, Seungjae Yoon, Dohyun Kim, Cheol Seong Hwang, Jung-Hae Choi
The in-plane tensile strain was reported to enhance the ferroelectricity of Hf1-xZrxO2 thin films by promoting the formation of the polar orthorhombic (PO-) phase. However, its origin remains yet to...
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Applications of peptide-based nanomaterials in targeting cancer therapy

Biomater. Sci., 2024, 12,1630-1642
DOI: 10.1039/D3BM02026F, Review Article
Beilei Sun, Limin Zhang, Mengzhen Li, Xin Wang, Weizhi Wang
To meet the precise diagnosis and treatment as well as reduce systemic toxicity and side effects, self-assembled peptides are applied to the targeting therapy, including targeting theranostics, nanocarrier delivery, immunotherapy, and combination therapy.
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A microneedle patch realizes weight loss through photothermal induction of fat browning

Biomater. Sci., 2024, 12,1726-1737
DOI: 10.1039/D3BM01767B, Paper
Zichun Gao, Yixuan Liu, Wenjiao Lin, He Lian, Zhaoxu Meng
Hyaluronic acid microneedles loaded with polydopamine nanoparticles induce fat browning, offering innovative localized obesity treatment.
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Efficient healing of diabetic wounds by MSC-EV-7A composite hydrogel via suppression of inflammation and enhancement of angiogenesis

Biomater. Sci., 2024, 12,1750-1760
DOI: 10.1039/D3BM01904G, Paper
Xinyi Long, Qian Yuan, Rui Tian, Wanting Zhang, Lang Liu, Minghui Yang, Xin Yuan, Zhujie Deng, Quanjiang Li, Ronghui Sun, Yuyi Kang, Yingying Peng, Xiubin Kuang, Lingfang Zeng, Zhengqiang Yuan
An alginate hydrogel loaded with mesenchymal stem-cell-derived extracellular vesicles (EVs) and a 7-amino-acid peptide (7A) constitutes a novel dressing for efficient healing of diabetic wounds with anti-inflammation and pro-angiogenesis mechanisms.
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Gelatine–collagen photo-crosslinkable 3D matrixes for skin regeneration

Biomater. Sci., 2024, 12,1738-1749
DOI: 10.1039/D3BM01849K, Paper
Open Access
Gauthier Menassol, Boudewijn van der Sanden, Laetitia Gredy, Capucine Arnol, Thibaut Divoux, Donald K. Martin, Olivier Stephan
Immediate care of skin wounds and burns is essential to repair this mechanical and chemical barrier to infections.
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Bi-functional quercetin/copper nanoparticles integrating bactericidal and anti-quorum sensing properties for preventing the formation of biofilms

Biomater. Sci., 2024, 12,1788-1800
DOI: 10.1039/D4BM00034J, Paper
Jingjing Cheng, Haixin Zhang, Kunyan Lu, Yi Zou, Dongxu Jia, Hong Yang, Hong Chen, Yanxia Zhang, Qian Yu
A bi-functional antibiofilm nanoplatform was developed based on a complex of quercetin and copper integrating bactericidal and anti-quorum sensing properties.
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Sorafenib and tetrakis (4-carboxyphenyl) porphyrin assembled nanoparticles for synergistic targeted chemotherapy and sonodynamic therapy of hepatocellular carcinoma

Biomater. Sci., 2024, 12,1864-1870
DOI: 10.1039/D3BM01994B, Paper
Yongzhi Chen, Qiuxia Tan, Yuanyu Tang, E. Pang, Rui Peng, Minhuan Lan, Dousheng Bai
Hepatocellular carcinoma (HCC) is characterized by a high degree of malignancy and mortality.
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Extracellular vesicles produced by 3D cultured MSCs promote wound healing by regulating macrophage activation through ANXA1

Biomater. Sci., 2024, 12,1761-1770
DOI: 10.1039/D3BM02035E, Paper
Hao Deng, Yuheng Jiang, Junhao Deng, Feifan Chang, Junyu Chen, Xinyu Sun, Dongliang Cheng, Zhongqi Wang, Ran Li, Jiang Liu, Yi Li, Licheng Zhang, Pengbin Yin
Extracellular vesicles (EVs) produced by 3D-cultured MSCs can modulate macrophage activation through ANXA1, thereby promoting wound healing.
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Fibromodulin facilitates the osteogenic effect of Masquelet's induced membrane by inhibiting the TGF-β/SMAD signaling pathway

Biomater. Sci., 2024, 12,1898-1913
DOI: 10.1039/D3BM01665J, Paper
Kai Wang, Ming Zhou, Yuanshu Zhang, Yesheng Jin, Yuan Xue, Dong Mao, Yongjun Rui
Schematic illustration of the mechanism by which an IM promotes bone formation. FMOD secreted by the IM promotes osteogenesis of BMSCs and angiogenesis of HUVECs by inhibiting the TGF-β/SMAD signaling pathway, thus facilitating bone formation.
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Application of a meshed artificial dermal scaffold and negative-pressure wound therapy in the treatment of full-thickness skin defects: a prospective in vivo study

Biomater. Sci., 2024, 12,1914-1923
DOI: 10.1039/D3BM01675G, Paper
Open Access
Pei Wei, Lijiao Wu, Hongteng Xie, Zhaohong Chen, Rongwei Tan, Zhaorong Xu
A novel meshed ADS combined with NPWT can reduce the risk of scaffold-related complications, which helps to improve the quality of wound repair and promotes a broader range of applications.
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Janus hydrogels: merging boundaries in tissue engineering for enhanced biomaterials and regenerative therapies

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01875J, Review Article
Yingxue Jiang, Chenhui Zhu, Xiaoxuan Ma, Daidi Fan
In recent years, the design and synthesis of Janus hydrogels have advanced significantly, overcoming single-performance material limitations and broadening applications in tissue engineering and regenerative medicine.
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Multifunctional antibacterial hydrogels for chronic wound management

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00155A, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yungang Hu, Lu Yu, Qiang Dai, Xiaohua Hu, Yuming Shen
Due to their distinctive physical and chemical properties as well as their biological functionalities, multifunctional antibacterial hydrogels possess significant advantages in the treatment of chronic wounds.
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Escape sites from the endo-lysosomal trafficking route manipulate exocytosis of nanoparticles in polar epithelium

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00174E, Paper
Lingling Wang, Yuting Li, Xi Liu, Liyun Xing, Ruinan Wu, Yuan Huang
MNPs escaping from early endosomes and late endosomes are prone to entering the ER/GA for efficient basolateral exocytosis. However, MNPs escaping from lysosomes are detained within cells by autophagosomes.
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Photothermal therapy: a novel potential treatment for prostate cancer

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00057A, Review Article
Zirui Dong, Kaming Xue, Anushikha Verma, Jian Shi, Zhihao Wei, Xiaotian Xia, Keshan Wang, Xiaoping Zhang
This review discussed photothermal therapy from basic information to its circumstances and potential in protate cancer treatment.
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Macrophage membrane-camouflaged nanoclusters of ultrasmall iron oxide nanoparticles for precision glioma theranostics

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00357H, Paper
Bin Zhang, Rui Yang, Hongwei Yu, Yamin Peng, Haoyu Huang, Meera Moydeen Abdul Hameed, Han Wang, Guixiang Zhang, Mohamed EL-Newehy, Mingwu Shen, Xiangyang Shi, Shaojun Peng
Macrophage membrane-camouflaged nanoclusters of ultrasmall iron oxide nanoparticles can be developed to cross the blood–brain barrier for magnetic resonance imaging and chemo/chemodynamic therapy.
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ABCD of IA: A multi-scale agent-based model of T cell activation in inflammatory arthritis

Biomater. Sci., 2024, 12,2041-2056
DOI: 10.1039/D3BM01674A, Paper
David A. McBride, James S. Wang, Wade T. Johnson, Nunzio Bottini, Nisarg J. Shah
The study develops a computational framework to model factors that lead to the evolution of autoreactive T cells in inflammatory arthritis. The results provide a tool for planning immunomodulatory strategies focused on new disease-modifying agents.
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PET image-guided kidney injury theranostics enabled by a bipyramidal DNA framework

Biomater. Sci., 2024, 12,2086-2095
DOI: 10.1039/D3BM01575K, Paper
Open Access
Pinghui Li, Zhidie Huang, Xiaoyan Duan, Tao Wang, Shaowen Yang, Dawei Jiang, Jianbo Li
We constructed 68Ga-BDF and employed PET imaging to establish its pharmacokinetic model. BDF was eliminated from the body via the urinary system. We observed distinct imaging indicators in UUO and AKI mouse models. Furthermore, we observed the therapeutic effect of BDF on AKI.
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Biomaterial engineering strategies for B cell immunity modulations

Biomater. Sci., 2024, 12,1981-2006
DOI: 10.1039/D3BM01841E, Review Article
Open Access
Ali Zareein, Mina Mahmoudi, Shruti Sunil Jadhav, Joel Wilmore, Yaoying Wu
Biomaterials enhance B cell immunity by modulating the delivery approach, crosslinking B cell receptors, and promoting T cell help, while inhibitory co-receptor engagement via biomaterial design suppresses B cell function.
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Neuroinflammatory response on a newly combinatorial cell–cell interaction chip

Biomater. Sci., 2024, 12,2096-2107
DOI: 10.1039/D4BM00125G, Paper
Yimeng Zhao, Xuefei Lv, Yu Chen, Chen Zhang, Di Zhou, Yulin Deng
Neuroinflammatory response on a novel combinatorial cell–cell interaction chip.
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Highly-ordered assembled organic fluorescent materials for high-resolution bio-sensing: a review

Biomater. Sci., 2024, 12,2019-2032
DOI: 10.1039/D3BM02070C, Review Article
Zheng Wang, Zilong Chen, Zhenhao Zhang, Hongzhen Wang, Haichang Zhang
Organic fluorescent materials (OFMs) play a crucial role in the development of biosensors, enabling the extraction of biochemical information within cells and organisms, extending to the human body.
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Recent progress in nanomaterials for bacteria-related tumor therapy

Biomater. Sci., 2024, 12,1965-1980
DOI: 10.1039/D3BM01952G, Review Article
Fuping Zhang, Shuyu Wang, Shuo Yang, Feihe Ma, Hui Gao
Recent progress in nanomaterials for bacteria-related tumor therapy in terms of chemotherapy, immunotherapy and synergistic therapy is summarized in this review in order to provide some insights into this emerging and rapidly growing research area.
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Liquid–liquid phase separation-inspired design of biomaterials

Biomater. Sci., 2024, 12,1943-1949
DOI: 10.1039/D3BM02008H, Minireview
Yang Song
Biological liquid–liquid phase separation (LLPS) provides novel insights for the assembly of biomaterials with tailored structure and intrinsic functionality.
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Enhancing antioxidant properties of CeO2 nanoparticles with Nd3+ doping: structural, biological, and machine learning insights

Biomater. Sci., 2024, 12,2108-2120
DOI: 10.1039/D3BM02107F, Paper
Oscar Ceballos-Sanchez, Diego E. Navarro-López, Jorge L. Mejía-Méndez, Gildardo Sanchez-Ante, Vicente Rodríguez-González, Angélica Lizeth Sánchez-López, Araceli Sanchez-Martinez, Sergio M. Duron-Torres, Karla Juarez-Moreno, Naveen Tiwari, Edgar R. López-Mena
The antioxidant capabilities of nanoparticles are contingent upon various factors, including their shape, size, and chemical composition.
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Design, manufacturing and testing of a green non-isocyanate polyurethane prosthetic heart valve

Biomater. Sci., 2024, 12,2149-2164
DOI: 10.1039/D3BM01911J, Paper
Open Access
Sofia F. Melo, Alicia Nondonfaz, Abdelhafid Aqil, Anna Pierrard, Alexia Hulin, Céline Delierneux, Bartosz Ditkowski, Maxime Gustin, Maxime Legrand, Bibian M. E. Tullemans, Sanne L. N. Brouns, Alain Nchimi, Raoul Carrus, Astrid Dejosé, Johan W. M. Heemskerk, Marijke J. E. Kuijpers, Jan Ritter, Ulrich Steinseifer, Johanna C. Clauser, Christine Jérôme, Patrizio Lancellotti, Cécile Oury
Non-isocyanate polyurethanes (NIPUs) were developed and tested in vitro. Prosthetic heart valves made of NIPU were designed and manufactured. NIPUs showed low thrombogenicity and the produced valves performed well in terms of hydrodynamics.
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Retraction: Strontium-doped gelatin scaffolds promote M2 macrophage switch and angiogenesis through modulating the polarization of neutrophils

Biomater. Sci., 2024, 12,2167-2167
DOI: 10.1039/D4BM90023E, Retraction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Tao Li, Hongtao He, Zezheng Yang, Junjie Wang, Yuxin Zhang, Guangxu He, Jun Huang, Deye Song, Jiangdong Ni, Xiaojun Zhou, Junfeng Zhu, Muliang Ding
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A thermally reversible injectable adhesive for intestine tissue repair and anti-postoperative adhesion

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00164H, Paper
Wenmo Zhang, Runze Zhang, Rong Yang, Yage Sun, Qian Zhang, Xuequan Feng, Chunyan Cui, Wenguang Liu
Intestine damage is an acute abdominal disease that usually requires emergency sealing. However, traditional surgical suture not only causes secondary damage to the injured tissue, but also results in adhesion...
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