em 'We Cannot Police Our Way Out of a Pandemic.' Experts, Police Union Say NYPD Should Not Be Enforcing Social Distance Rules Amid COVID-19 By news.yahoo.com Published On :: Thu, 07 May 2020 17:03:38 -0400 The New York City police department (NYPD) is conducting an internal investigation into a May 2 incident involving the violent arrests of multiple people, allegedly members of a group who were not social distancing Full Article
em The accusation against Joe Biden has Democrats rediscovering the value of due process By news.yahoo.com Published On :: Sat, 09 May 2020 08:37:00 -0400 Some Democrats took "Believe Women" literally until Joe Biden was accused. Now they're relearning that guilt-by-accusation doesn't serve justice. Full Article
em Coronavirus: Chinese official admits health system weaknesses By news.yahoo.com Published On :: Sat, 09 May 2020 11:02:40 -0400 China says it will improve public health systems after criticism of its early response to the virus. Full Article
em Learning Semiparametric Regression with Missing Covariates Using Gaussian Process Models By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Abhishek Bishoyi, Xiaojing Wang, Dipak K. Dey. Source: Bayesian Analysis, Volume 15, Number 1, 215--239.Abstract: Missing data often appear as a practical problem while applying classical models in the statistical analysis. In this paper, we consider a semiparametric regression model in the presence of missing covariates for nonparametric components under a Bayesian framework. As it is known that Gaussian processes are a popular tool in nonparametric regression because of their flexibility and the fact that much of the ensuing computation is parametric Gaussian computation. However, in the absence of covariates, the most frequently used covariance functions of a Gaussian process will not be well defined. We propose an imputation method to solve this issue and perform our analysis using Bayesian inference, where we specify the objective priors on the parameters of Gaussian process models. Several simulations are conducted to illustrate effectiveness of our proposed method and further, our method is exemplified via two real datasets, one through Langmuir equation, commonly used in pharmacokinetic models, and another through Auto-mpg data taken from the StatLib library. Full Article
em Bayesian Design of Experiments for Intractable Likelihood Models Using Coupled Auxiliary Models and Multivariate Emulation By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Antony Overstall, James McGree. Source: Bayesian Analysis, Volume 15, Number 1, 103--131.Abstract: A Bayesian design is given by maximising an expected utility over a design space. The utility is chosen to represent the aim of the experiment and its expectation is taken with respect to all unknowns: responses, parameters and/or models. Although straightforward in principle, there are several challenges to finding Bayesian designs in practice. Firstly, the utility and expected utility are rarely available in closed form and require approximation. Secondly, the design space can be of high-dimensionality. In the case of intractable likelihood models, these problems are compounded by the fact that the likelihood function, whose evaluation is required to approximate the expected utility, is not available in closed form. A strategy is proposed to find Bayesian designs for intractable likelihood models. It relies on the development of an automatic, auxiliary modelling approach, using multivariate Gaussian process emulators, to approximate the likelihood function. This is then combined with a copula-based approach to approximate the marginal likelihood (a quantity commonly required to evaluate many utility functions). These approximations are demonstrated on examples of stochastic process models involving experimental aims of both parameter estimation and model comparison. Full Article
em Scalable Bayesian Inference for the Inverse Temperature of a Hidden Potts Model By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Matthew Moores, Geoff Nicholls, Anthony Pettitt, Kerrie Mengersen. Source: Bayesian Analysis, Volume 15, Number 1, 1--27.Abstract: The inverse temperature parameter of the Potts model governs the strength of spatial cohesion and therefore has a major influence over the resulting model fit. A difficulty arises from the dependence of an intractable normalising constant on the value of this parameter and thus there is no closed-form solution for sampling from the posterior distribution directly. There is a variety of computational approaches for sampling from the posterior without evaluating the normalising constant, including the exchange algorithm and approximate Bayesian computation (ABC). A serious drawback of these algorithms is that they do not scale well for models with a large state space, such as images with a million or more pixels. We introduce a parametric surrogate model, which approximates the score function using an integral curve. Our surrogate model incorporates known properties of the likelihood, such as heteroskedasticity and critical temperature. We demonstrate this method using synthetic data as well as remotely-sensed imagery from the Landsat-8 satellite. We achieve up to a hundredfold improvement in the elapsed runtime, compared to the exchange algorithm or ABC. An open-source implementation of our algorithm is available in the R package bayesImageS . Full Article
em Bayes Factors for Partially Observed Stochastic Epidemic Models By projecteuclid.org Published On :: Tue, 11 Jun 2019 04:00 EDT Muteb Alharthi, Theodore Kypraios, Philip D. O’Neill. Source: Bayesian Analysis, Volume 14, Number 3, 927--956.Abstract: We consider the problem of model choice for stochastic epidemic models given partial observation of a disease outbreak through time. Our main focus is on the use of Bayes factors. Although Bayes factors have appeared in the epidemic modelling literature before, they can be hard to compute and little attention has been given to fundamental questions concerning their utility. In this paper we derive analytic expressions for Bayes factors given complete observation through time, which suggest practical guidelines for model choice problems. We adapt the power posterior method for computing Bayes factors so as to account for missing data and apply this approach to partially observed epidemics. For comparison, we also explore the use of a deviance information criterion for missing data scenarios. The methods are illustrated via examples involving both simulated and real data. Full Article
em Jointly Robust Prior for Gaussian Stochastic Process in Emulation, Calibration and Variable Selection By projecteuclid.org Published On :: Tue, 11 Jun 2019 04:00 EDT Mengyang Gu. Source: Bayesian Analysis, Volume 14, Number 3, 877--905.Abstract: Gaussian stochastic process (GaSP) has been widely used in two fundamental problems in uncertainty quantification, namely the emulation and calibration of mathematical models. Some objective priors, such as the reference prior, are studied in the context of emulating (approximating) computationally expensive mathematical models. In this work, we introduce a new class of priors, called the jointly robust prior, for both the emulation and calibration. This prior is designed to maintain various advantages from the reference prior. In emulation, the jointly robust prior has an appropriate tail decay rate as the reference prior, and is computationally simpler than the reference prior in parameter estimation. Moreover, the marginal posterior mode estimation with the jointly robust prior can separate the influential and inert inputs in mathematical models, while the reference prior does not have this property. We establish the posterior propriety for a large class of priors in calibration, including the reference prior and jointly robust prior in general scenarios, but the jointly robust prior is preferred because the calibrated mathematical model typically predicts the reality well. The jointly robust prior is used as the default prior in two new R packages, called “RobustGaSP” and “RobustCalibration”, available on CRAN for emulation and calibration, respectively. Full Article
em Semiparametric Multivariate and Multiple Change-Point Modeling By projecteuclid.org Published On :: Tue, 11 Jun 2019 04:00 EDT Stefano Peluso, Siddhartha Chib, Antonietta Mira. Source: Bayesian Analysis, Volume 14, Number 3, 727--751.Abstract: We develop a general Bayesian semiparametric change-point model in which separate groups of structural parameters (for example, location and dispersion parameters) can each follow a separate multiple change-point process, driven by time-dependent transition matrices among the latent regimes. The distribution of the observations within regimes is unknown and given by a Dirichlet process mixture prior. The properties of the proposed model are studied theoretically through the analysis of inter-arrival times and of the number of change-points in a given time interval. The prior-posterior analysis by Markov chain Monte Carlo techniques is developed on a forward-backward algorithm for sampling the various regime indicators. Analysis with simulated data under various scenarios and an application to short-term interest rates are used to show the generality and usefulness of the proposed model. Full Article
em Alleviating Spatial Confounding for Areal Data Problems by Displacing the Geographical Centroids By projecteuclid.org Published On :: Fri, 31 May 2019 22:05 EDT Marcos Oliveira Prates, Renato Martins Assunção, Erica Castilho Rodrigues. Source: Bayesian Analysis, Volume 14, Number 2, 623--647.Abstract: Spatial confounding between the spatial random effects and fixed effects covariates has been recently discovered and showed that it may bring misleading interpretation to the model results. Techniques to alleviate this problem are based on decomposing the spatial random effect and fitting a restricted spatial regression. In this paper, we propose a different approach: a transformation of the geographic space to ensure that the unobserved spatial random effect added to the regression is orthogonal to the fixed effects covariates. Our approach, named SPOCK, has the additional benefit of providing a fast and simple computational method to estimate the parameters. Also, it does not constrain the distribution class assumed for the spatial error term. A simulation study and real data analyses are presented to better understand the advantages of the new method in comparison with the existing ones. Full Article
em An Overview of Semiparametric Extensions of Finite Mixture Models By projecteuclid.org Published On :: Fri, 11 Oct 2019 04:03 EDT Sijia Xiang, Weixin Yao, Guangren Yang. Source: Statistical Science, Volume 34, Number 3, 391--404.Abstract: Finite mixture models have offered a very important tool for exploring complex data structures in many scientific areas, such as economics, epidemiology and finance. Semiparametric mixture models, which were introduced into traditional finite mixture models in the past decade, have brought forth exciting developments in their methodologies, theories, and applications. In this article, we not only provide a selective overview of the newly-developed semiparametric mixture models, but also discuss their estimation methodologies, theoretical properties if applicable, and some open questions. Recent developments are also discussed. Full Article
em Rejoinder: Bayes, Oracle Bayes, and Empirical Bayes By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Bradley Efron. Source: Statistical Science, Volume 34, Number 2, 234--235. Full Article
em Comment: Variational Autoencoders as Empirical Bayes By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Yixin Wang, Andrew C. Miller, David M. Blei. Source: Statistical Science, Volume 34, Number 2, 229--233. Full Article
em Comment: Empirical Bayes, Compound Decisions and Exchangeability By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Eitan Greenshtein, Ya’acov Ritov. Source: Statistical Science, Volume 34, Number 2, 224--228.Abstract: We present some personal reflections on empirical Bayes/ compound decision (EB/CD) theory following Efron (2019). In particular, we consider the role of exchangeability in the EB/CD theory and how it can be achieved when there are covariates. We also discuss the interpretation of EB/CD confidence interval, the theoretical efficiency of the CD procedure, and the impact of sparsity assumptions. Full Article
em Comment: Empirical Bayes Interval Estimation By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Wenhua Jiang. Source: Statistical Science, Volume 34, Number 2, 219--223.Abstract: This is a contribution to the discussion of the enlightening paper by Professor Efron. We focus on empirical Bayes interval estimation. We discuss the oracle interval estimation rules, the empirical Bayes estimation of the oracle rule and the computation. Some numerical results are reported. Full Article
em Comment: Bayes, Oracle Bayes and Empirical Bayes By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Aad van der Vaart. Source: Statistical Science, Volume 34, Number 2, 214--218. Full Article
em Comment: Bayes, Oracle Bayes, and Empirical Bayes By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Nan Laird. Source: Statistical Science, Volume 34, Number 2, 206--208. Full Article
em Comment: Bayes, Oracle Bayes, and Empirical Bayes By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Thomas A. Louis. Source: Statistical Science, Volume 34, Number 2, 202--205. Full Article
em Bayes, Oracle Bayes and Empirical Bayes By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Bradley Efron. Source: Statistical Science, Volume 34, Number 2, 177--201.Abstract: This article concerns the Bayes and frequentist aspects of empirical Bayes inference. Some of the ideas explored go back to Robbins in the 1950s, while others are current. Several examples are discussed, real and artificial, illustrating the two faces of empirical Bayes methodology: “oracle Bayes” shows empirical Bayes in its most frequentist mode, while “finite Bayes inference” is a fundamentally Bayesian application. In either case, modern theory and computation allow us to present a sharp finite-sample picture of what is at stake in an empirical Bayes analysis. Full Article
em Jennifer Lopez Is Wearing the Hell Out of These $60 Sneakers—and You Can Buy Them at Zappos By www.health.com Published On :: Mon, 22 Jul 2019 17:56:20 -0400 The chic sneaks are part of Zappos' massive Cyber Monday sale. Full Article
em Jennifer Lopez Just Stepped Out in These Glittery Leggings (Again)—and We Found Them on Sale By www.health.com Published On :: Thu, 12 Dec 2019 16:14:56 -0500 They’re already going out of stock. Full Article
em Shoppers Swear These $30 Colorfulkoala Leggings Are the Ultimate Lululemon Dupes By www.health.com Published On :: Wed, 11 Dec 2019 12:44:27 -0500 And they’re available in 19 fun prints. Full Article
em Allometric Analysis Detects Brain Size-Independent Effects of Sex and Sex Chromosome Complement on Human Cerebellar Organization By www.jneurosci.org Published On :: 2017-05-24 Catherine MankiwMay 24, 2017; 37:5221-5231Development Plasticity Repair Full Article
em Memory and Brain Systems: 1969-2009 By www.jneurosci.org Published On :: 2009-10-14 Larry R. SquireOct 14, 2009; 29:12711-1271640th Anniversary Retrospective Full Article
em Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome By www.jneurosci.org Published On :: 2020-02-12 Irune Diaz-AparicioFeb 12, 2020; 40:1453-1482Development Plasticity Repair Full Article
em The Representation of Semantic Information Across Human Cerebral Cortex During Listening Versus Reading Is Invariant to Stimulus Modality By www.jneurosci.org Published On :: 2019-09-25 Fatma DenizSep 25, 2019; 39:7722-7736BehavioralSystemsCognitive Full Article
em Fingolimod Rescues Demyelination in a Mouse Model of Krabbe's Disease By www.jneurosci.org Published On :: 2020-04-08 Sibylle BéchetApr 8, 2020; 40:3104-3118Neurobiology of Disease Full Article
em Dural Calcitonin Gene-Related Peptide Produces Female-Specific Responses in Rodent Migraine Models By www.jneurosci.org Published On :: 2019-05-29 Amanda AvonaMay 29, 2019; 39:4323-4331Systems/Circuits Full Article
em Where Is the Anterior Temporal Lobe and What Does It Do? By www.jneurosci.org Published On :: 2013-03-06 Michael F. BonnerMar 6, 2013; 33:4213-4215Journal Club Full Article
em Grey Matter Volume Differences Associated with Extremely Low Levels of Cannabis Use in Adolescence By www.jneurosci.org Published On :: 2019-03-06 Catherine OrrMar 6, 2019; 39:1817-1827BehavioralSystemsCognitive Full Article
em Indigenous peoples and dementia : new understandings of memory loss and memory care By dal.novanet.ca Published On :: Fri, 1 May 2020 19:36:42 -0300 Callnumber: RC 521 I53 2019ISBN: 9780774837835 (hardcover) Full Article
em Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state By www.jneurosci.org Published On :: 1993-04-01 CJ PikeApr 1, 1993; 13:1676-1687Articles Full Article
em Neural Mechanisms of Visual Working Memory in Prefrontal Cortex of the Macaque By www.jneurosci.org Published On :: 1996-08-15 Earl K. MillerAug 15, 1996; 16:5154-5167Articles Full Article
em Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases By www.jneurosci.org Published On :: 1996-04-01 M NiethammerApr 1, 1996; 16:2157-2163Articles Full Article
em A selective impairment of motion perception following lesions of the middle temporal visual area (MT) By www.jneurosci.org Published On :: 1988-06-01 WT NewsomeJun 1, 1988; 8:2201-2211Articles Full Article
em Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems By www.jneurosci.org Published On :: 1998-12-01 Christelle PeyronDec 1, 1998; 18:9996-10015Articles Full Article
em A framework for mesencephalic dopamine systems based on predictive Hebbian learning By www.jneurosci.org Published On :: 1996-03-01 PR MontagueMar 1, 1996; 16:1936-1947Articles Full Article
em The highly irregular firing of cortical cells is inconsistent with temporal integration of random EPSPs By www.jneurosci.org Published On :: 1993-01-01 WR SoftkyJan 1, 1993; 13:334-350Articles Full Article
em Cortical Excitatory Neurons and Glia, But Not GABAergic Neurons, Are Produced in the Emx1-Expressing Lineage By www.jneurosci.org Published On :: 2002-08-01 Jessica A. GorskiAug 1, 2002; 22:6309-6314BRIEF COMMUNICATION Full Article
em Linear Systems Analysis of Functional Magnetic Resonance Imaging in Human V1 By www.jneurosci.org Published On :: 1996-07-01 Geoffrey M. BoyntonJul 1, 1996; 16:4207-4221Articles Full Article
em Rassegna trimestrale BRI settembre 2017: Le prospettive positive in un contesto di bassa inflazione alimentano l'assunzione di rischio By www.bis.org Published On :: 2017-09-17T16:00:00Z Italian translation of the BIS press release about the BIS Quarterly Review, September 2017 Full Article
em Rassegna trimestrale BRI, settembre 2017 By www.bis.org Published On :: 2017-09-17T16:00:00Z Italian translation of the BIS Quarterly Review, September 2017 Full Article
em Rassegna trimestrale BRI, dicembre 2017 By www.bis.org Published On :: 2017-12-03T17:00:00Z Italian translation of the BIS Quarterly Review, December 2017 Full Article
em Rassegna trimestrale BRI dicembre 2017: Un paradossale inasprimento ci riporta all'enigma del mercato obbligazionario By www.bis.org Published On :: 2017-12-03T17:00:00Z Italian translation of the BIS press release about the BIS Quarterly Review, December 2017 Full Article
em Rassegna trimestrale BRI, settembre 2018 By www.bis.org Published On :: 2018-09-23T16:00:00Z Italian translation of the BIS Quarterly Review, September 2018 Full Article
em Rassegna trimestrale BRI, dicembre 2018 By www.bis.org Published On :: 2018-12-16T17:00:00Z Italian translation of the BIS Quarterly Review, December 2018 Full Article
em Le Comité de Bâle finalise sa revue du traitement réglementaire des expositions aux actifs souverains sans modifier les règles existantes et publie un document de discussion By www.bis.org Published On :: 2017-12-07T16:00:00Z French translation of the press release about the Basel Committee publishing a discussion paper on "The regulatory treatment of sovereign exposures" (7 December 2017) Full Article
em Questions fréquemment posées sur les exigences de fonds propres en regard du risque de marché By www.bis.org Published On :: 2018-03-28T13:34:00Z French translation of "Frequently asked questions on market risk capital requirements" by the Basel Committee, March 2018. Full Article
em Le Communiqué de Bâle finalise les principes relatifs aux tests de résistance, passe en revue les moyens pour mettre fin aux comportements d'arbitrage réglementaire, s'accorde sur la liste annuelle des G-SIB et discute du ratio By www.bis.org Published On :: 2018-09-20T14:00:00Z French translation of press release - the Basel Committee on Banking Supervision is finalising stress-testing principles, reviews ways to stop regulatory arbitrage behaviour, agrees on annual G-SIB list, discusses leverage ratio, crypto-assets, market risk framework and implementation, 20 September 2018. Full Article
em Rapport trimestriel BRI, septembre 2018 By www.bis.org Published On :: 2018-09-23T16:00:00Z French translation of the BIS Quarterly Review, September 2018 Full Article